55例腰椎管内神经鞘瘤导致体位性神经根性疼痛的原因分析
|
摘要
目的:通过对出现根性疼痛症状的腰椎管内神经鞘瘤病例的总结,发现其根性疼痛与体位的相关性。方法:回顾性分析55例腰椎管内神经鞘瘤的典型临床表现,并查阅相关文献探讨体位与神经根性疼痛的原因。结果:55例腰椎管内神经鞘瘤患者均有明显的体位相关性神经根痛。结论:腰椎管内神经鞘瘤可导致患者出现体位性神经根痛,并可以此与腰椎间盘突出和腰椎管狭窄症等退行性疾病所致根性疼痛相鉴别,有助于腰椎管内神经鞘瘤的早期诊断和手术治疗,对于提高患者的生活质量具有重要的意义。
Objective:To find the correlation between the root pain and the position of the spinal canal by summarizing the cases of neurilemmoma in the lumbar spinal canal with the symptoms of root pain.Methods:The typical clinical manifestations of 55 cases of neurilemmoma in lumbar spinal canal were analyzed retrospectively,and the causes of body position and nerve root type pain were discussed.Results:55 patients with neurilemmoma in the lumbar spinal canal had obvious position-related nerve root pain.Conclusion:Lumbar spinal neurilemmoma can lead to patients with position-related nerve root pain,and this can be diagnosed differentially with lumbar disc herniation and lumbar spinal canal stenosis and other degenerative diseases.Early diagnosis and surgical treatment of lumbar spinal canal neurilemmoma is of great significance to improve the quality of patients' life.
Objective:To find the correlation between the root pain and the position of the spinal canal by summarizing the cases of neurilemmoma in the lumbar spinal canal with the symptoms of root pain.Methods:The typical clinical manifestations of 55 cases of neurilemmoma in lumbar spinal canal were analyzed retrospectively,and the causes of body position and nerve root type pain were discussed.Results:55 patients with neurilemmoma in the lumbar spinal canal had obvious position-related nerve root pain.Conclusion:Lumbar spinal neurilemmoma can lead to patients with position-related nerve root pain,and this can be diagnosed differentially with lumbar disc herniation and lumbar spinal canal stenosis and other degenerative diseases.Early diagnosis and surgical treatment of lumbar spinal canal neurilemmoma is of great significance to improve the quality of patients' life.
引文
[1]Hirano K,Imagama S,Sato K,et al.Primary spinal cord tumors:review of 678 surgically treated patients in Japan.A multicenter study[J].Eur Spine J,2012,21(10):2019-2026.
[2]Ando K,Imagama S,Ito Z,et al.How do spinal schwannomas progress?The natural progression of spinal schwannomas on MRI[J].J Neurosurg Spine,2016,24(1):155-159.
[3]Blond S,Mertens P,David R,et al.From"mechanical"to"neuropathic"back pain concept in FBSS patients.A systematic review based on factors leading to the chronification of pain(part C)[J].Neurochirurgie,2015,61(Suppl 1):S45-56.
[4]Liebelt BD,Haider AS,Steele WJ,et al.Spinal schwannoma and meningioma mimicking a single mass at the craniocervical junction subsequent to remote radiation therapy for acne vulgaris[J].World Neurosurg,2016,93:484.e13-16.
[5]Gooyers CE,Callaghan JP.Exploring interactions between force,repetition and posture on intervertebral disc height loss and bulging in isolated porcine cervical functional spinal units from sub-acute-failure magnitudes of cyclic compressive loading[J].J Biomech,2015,48(13):3701-3708.
[6]Shymon S,Hargens AR,Minkoff LA,et al.Body posture and backpack loading:an upright magnetic resonance imaging study of the adult lumbar spine[J].Eur Spine J,2014,23(7):1407-1413.
[7]Paiva T,Gaspar T,Matos MG.Sleep deprivation in adolescents:correlations with health complaints and health-related quality of life[J].Sleep Med,2015,16(4):521-527.
[8]Ramos RM,da Costa RC,Oliveira AL,et al.Morphological changes of the caudal cervical intervertebral foramina due to flexion-extension and compression-traction movements in the canine cervical vertebral column[J].BMC Vet Res,2015,11:184.
[9]Chen B,Liu Y,Zhang Y,et al.IL-21 is positively associated with intervertebral disc degeneration by interaction with TNF-αthrough the JAK-STAT signaling pathway[J].Inflammation,2017,40(2):612-622.
[10]Hamm-Faber TE,Aukes H,van Gorp EJ,et al.Subcutaneous stimulation as an additional therapy to spinal cord stimulation for the treatment of low back pain and leg pain in failed back surgery syndrome:Four-year follow-up[J].Neuromodulation,2015,18(7):618-622.
[11]Tachibana T,Maruo K,Inoue S,et al.Use of pain drawing as an assessment tool of sciatica for patients with single level lumbar disc herniation[J].Springerplus,2016,5(1):1312.
[12]Eljebbouri B,Salami M,Gazzaz M,et al.A 23-year-old spinal textiloma after discectomy for lumbar disc herniation[J].Spine J,2014,14(11):2782.
[13]Wang W,Atianjoh F,Gauda EB,et al.Increased expression of sodium channel subunit Nav1.1 in the injured dorsal root ganglion after peripheral nerve injury[J].Anat Rec(Hoboken),2011,294(8):1406-1411.
[14]Martini AC,Berta T,Forner S,et al.Lipoxin A4 inhibits microglial activation and reduces neuroinflammation and neuropathic pain after spinal cord hemisection[J].J Neuroinflammation,2016,13(1):75.
[15]Zhu XL,Chen X,Wang W,et al.Electroacupuncture pretreatment attenuates spinal cord ischemia-reperfusion injury via inhibition of high-mobility group box 1 production in a LXA4 receptordependent manner[J].Brain Res,2017,1659:113-120.
[16]Sommer JB,Bach A,MaláH,et al.In vitro and in vivo effects of a novel dimeric inhibitor of PSD-95 on excitotoxicity and functional recovery after experimental traumatic brain injury[J].Eur JNeurosci,2017,45(2):238-248.
[17]Dong Y,Kalueff AV,Song C.N-methyl-d-aspartate receptor-mediated calcium overload and endoplasmic reticulum stress are involved in interleukin-1beta-induced neuronal apoptosis in rat hippocampus[J].J Neuroimmunol,2017,307:7-13.
[2]Ando K,Imagama S,Ito Z,et al.How do spinal schwannomas progress?The natural progression of spinal schwannomas on MRI[J].J Neurosurg Spine,2016,24(1):155-159.
[3]Blond S,Mertens P,David R,et al.From"mechanical"to"neuropathic"back pain concept in FBSS patients.A systematic review based on factors leading to the chronification of pain(part C)[J].Neurochirurgie,2015,61(Suppl 1):S45-56.
[4]Liebelt BD,Haider AS,Steele WJ,et al.Spinal schwannoma and meningioma mimicking a single mass at the craniocervical junction subsequent to remote radiation therapy for acne vulgaris[J].World Neurosurg,2016,93:484.e13-16.
[5]Gooyers CE,Callaghan JP.Exploring interactions between force,repetition and posture on intervertebral disc height loss and bulging in isolated porcine cervical functional spinal units from sub-acute-failure magnitudes of cyclic compressive loading[J].J Biomech,2015,48(13):3701-3708.
[6]Shymon S,Hargens AR,Minkoff LA,et al.Body posture and backpack loading:an upright magnetic resonance imaging study of the adult lumbar spine[J].Eur Spine J,2014,23(7):1407-1413.
[7]Paiva T,Gaspar T,Matos MG.Sleep deprivation in adolescents:correlations with health complaints and health-related quality of life[J].Sleep Med,2015,16(4):521-527.
[8]Ramos RM,da Costa RC,Oliveira AL,et al.Morphological changes of the caudal cervical intervertebral foramina due to flexion-extension and compression-traction movements in the canine cervical vertebral column[J].BMC Vet Res,2015,11:184.
[9]Chen B,Liu Y,Zhang Y,et al.IL-21 is positively associated with intervertebral disc degeneration by interaction with TNF-αthrough the JAK-STAT signaling pathway[J].Inflammation,2017,40(2):612-622.
[10]Hamm-Faber TE,Aukes H,van Gorp EJ,et al.Subcutaneous stimulation as an additional therapy to spinal cord stimulation for the treatment of low back pain and leg pain in failed back surgery syndrome:Four-year follow-up[J].Neuromodulation,2015,18(7):618-622.
[11]Tachibana T,Maruo K,Inoue S,et al.Use of pain drawing as an assessment tool of sciatica for patients with single level lumbar disc herniation[J].Springerplus,2016,5(1):1312.
[12]Eljebbouri B,Salami M,Gazzaz M,et al.A 23-year-old spinal textiloma after discectomy for lumbar disc herniation[J].Spine J,2014,14(11):2782.
[13]Wang W,Atianjoh F,Gauda EB,et al.Increased expression of sodium channel subunit Nav1.1 in the injured dorsal root ganglion after peripheral nerve injury[J].Anat Rec(Hoboken),2011,294(8):1406-1411.
[14]Martini AC,Berta T,Forner S,et al.Lipoxin A4 inhibits microglial activation and reduces neuroinflammation and neuropathic pain after spinal cord hemisection[J].J Neuroinflammation,2016,13(1):75.
[15]Zhu XL,Chen X,Wang W,et al.Electroacupuncture pretreatment attenuates spinal cord ischemia-reperfusion injury via inhibition of high-mobility group box 1 production in a LXA4 receptordependent manner[J].Brain Res,2017,1659:113-120.
[16]Sommer JB,Bach A,MaláH,et al.In vitro and in vivo effects of a novel dimeric inhibitor of PSD-95 on excitotoxicity and functional recovery after experimental traumatic brain injury[J].Eur JNeurosci,2017,45(2):238-248.
[17]Dong Y,Kalueff AV,Song C.N-methyl-d-aspartate receptor-mediated calcium overload and endoplasmic reticulum stress are involved in interleukin-1beta-induced neuronal apoptosis in rat hippocampus[J].J Neuroimmunol,2017,307:7-13.