左西孟旦治疗老年缺血性心肌病临床效果分析
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摘要
目的分析老年缺血性心肌病(ICD)所致急性失代偿性心力衰竭(ADHF)者应用左西孟旦医治的临床效果及预后。方法对本院2017年3月～2018年4月收治老年ICD所致ADHF82例患者临床资料加以分析,依据不同医治方法分为两组,将行常规方法医治41例患者作为对照组,将行左西孟旦医治41例患者作为研究组,比较两组临床效果、及预后。结果研究组N末端钠尿肽前体和左心射血分数均较对照组优;两组心率、血压和肌酐水平对比均无显著差异;研究组预后总体健康得分比对照组高,组间比较均有统计学意义(P <0.05)。结论老年ICD所致ADHF者应用左西孟旦医治可降低N末端钠尿肽前体水平和升高左心射血分数,促进患者生活质量提高,且患者心率、血压等无异常,值得应用。
Objective To analyze the clinical effect and prognosis of patients with acute decompensated heart failure(ADHF) induced by ischemic cardiomyopathy(ICD) using levosimendan. Methods The clinical data of 82 patients with ADHF due to elderly ICD admitted from March 2017 to April 2018 in our hospital were analyzed. The patients were divided into two groups according to different treatment Methods. The routine treatment of 41 patients as a control group was performed. West Mengdan treated 41 patients as a study group to compare the clinical efficacy and prognosis of the two groups. Results The N-terminal natriuretic peptide precursor and left ventricular ejection fraction in the study group were superior to those in the control group; heart rate, blood pressure, and creatinine in the two groups. There was no significant difference in the levels. The overall health score in the study group was higher than that in the control group(P < 0.05). Conclusion Treatment of ADHF patients with ADHF caused by elderly ICD can reduce the N-terminal natriuretic peptide precursor level and increase the left cardiac ejection fraction, and promote the quality of life of patients. There is no abnormality in heart rate, blood pressure, etc.,and it is worth promoting.
Objective To analyze the clinical effect and prognosis of patients with acute decompensated heart failure(ADHF) induced by ischemic cardiomyopathy(ICD) using levosimendan. Methods The clinical data of 82 patients with ADHF due to elderly ICD admitted from March 2017 to April 2018 in our hospital were analyzed. The patients were divided into two groups according to different treatment Methods. The routine treatment of 41 patients as a control group was performed. West Mengdan treated 41 patients as a study group to compare the clinical efficacy and prognosis of the two groups. Results The N-terminal natriuretic peptide precursor and left ventricular ejection fraction in the study group were superior to those in the control group; heart rate, blood pressure, and creatinine in the two groups. There was no significant difference in the levels. The overall health score in the study group was higher than that in the control group(P < 0.05). Conclusion Treatment of ADHF patients with ADHF caused by elderly ICD can reduce the N-terminal natriuretic peptide precursor level and increase the left cardiac ejection fraction, and promote the quality of life of patients. There is no abnormality in heart rate, blood pressure, etc.,and it is worth promoting.
引文
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[10]张晓娟,李保,王敬萍.左西孟旦、米力农和多巴酚丁胺治疗急性心力衰竭的对比研究[J].中西医结合心脑血管病杂志,2015,(5):631-634.
[11]李雅男,苏鹏宇.米力农和左西孟旦对失代偿心力衰竭患者脑利钠肽水平和心功能的影响比较[J].中国药业,2016,25(17):53-56.
[12]姚瑞,孙同文,杜优优,等.左西孟旦治疗急性心力衰竭的随机对照临床研究[J].中华急诊医学杂志,2015,24(8):893-896.
[2]季华庆,石建国.国内重症监护病房应用无创呼吸机治疗急性心力衰竭合并呼吸衰竭疗效的Meta分析[J].中国现代医学杂志,2016,26(7):33-39.
[3]杨敬,华琦,李静,等.急性心力衰竭住院患者的药物治疗分析--多中心现况调查[J].首都医科大学学报,2015,36(3):410-413.
[4]贺文奇,楚英杰.老年急性失代偿心力衰竭患者临床特点及近期预后危险因素分析[J].中华老年医学杂志,2016,35(1):8-12.
[5]董爱淑,陈茜茜,吴敏敏,等.扩张型心肌病心力衰竭阶段患者健康相关生命质量评价及影响因素分析[J].中华健康管理学杂志,2016,10(2):131-136.
[6]张海珍,李翠莲.重组人脑利钠肽治疗急性失代偿心力衰竭的临床疗效及对炎症因子的影响[J].重庆医学,2016,45(34):4850-4851,4889.
[7]顾永伟,许康世,朱成振,等.急性失代偿心力衰竭病人应用重组人脑利钠肽治疗的效果观察[J].中西医结合心脑血管病杂志,2017,15(21):2729-2731.
[8]杨晶敏,张洁钰,张菲斐.失代偿心力衰竭患者血钠水平与三尖瓣收缩期位移及肾小球滤过率的关系[J].医学研究杂志,2017,46(11):116-120.
[9]孙俊丽,郑有光,陈叶柔,等.左西孟旦治疗老年急性失代偿性心力衰竭的疗效[J].中国老年学杂志,2015,(20):5770-5771.
[10]张晓娟,李保,王敬萍.左西孟旦、米力农和多巴酚丁胺治疗急性心力衰竭的对比研究[J].中西医结合心脑血管病杂志,2015,(5):631-634.
[11]李雅男,苏鹏宇.米力农和左西孟旦对失代偿心力衰竭患者脑利钠肽水平和心功能的影响比较[J].中国药业,2016,25(17):53-56.
[12]姚瑞,孙同文,杜优优,等.左西孟旦治疗急性心力衰竭的随机对照临床研究[J].中华急诊医学杂志,2015,24(8):893-896.