左归饮加减对眩晕肾精不足证患者临床疗效及生活质量的影响
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摘要
目的:观察左归饮加减对眩晕肾精不足证患者临床疗效及生活质量的影响。方法:将本院2013年8月至2018年3月收治的眩晕肾精不足证患者70例随机分为对照组和观察组各35例,对照组给予常规西药治疗,观察组在常规西药治疗基础上采用左归饮加减治疗,观察两组患者眩晕症状、临床疗效及生活质量改善情况。结果:观察组治疗后眩晕持续时间显著短于对照组(P <0. 05),基底动脉(arteriae basilaris,BA)、椎基底动脉(vertebrobasilar artery,VA)、大脑后动脉(posterior cerebrl arteriae,PCA)水平均高于对照组(t=7. 091、2. 657、2. 408、2. 531,P <0. 05);观察组有效率为94. 29%,高于对照组的74. 29%(P <0. 05);观察组不良反应发生率为8. 57%,显著低于对照组的20. 00%(χ2=5. 285、4. 200,P <0. 05);观察组治疗后SF-36量表各项内容评分均显著高于对照组(P <0. 05)。结论:左归饮加减可显著改善眩晕肾精不足证患者眩晕症状,提高其生活质量。
Objective: To observe the influence of Modified Left Metal Decoction on clinical Efficacy and life quality of patients with vertigo with kidney essence deficiency syndrome. Methods: Seventy patients with vertigo with kidney essence deficiency syndrome admitted to our hospital from August 2013 to March 2018 were randomly divided into the control group and the observation group,with 35 cases in each group. The control group was treated with conventional Western medicine,while the observation group was treated with Left Metal Decoction on the basis of conventional Western medicine. The vertigo symptoms,clinical efficacy and quality of life of the two groups were observed. Results: After the treatment,the duration of vertigo in the observation group was significantly shorter than that in the control group( P < 0. 05),and the levels of basilar artery( BA),vertebrobasilar artery( VA),posterior cerebral artery( PCA) in the observation group were higher than those in the control group( t = 7. 091,2. 657,2. 408,2. 531,P < 0. 05). The effective rate in the observation group was 94. 29%,which was higher than that in the control group( 74. 29%,P < 0. 05). The incidence of adverse reactions in the observation group was 8. 57%,which was significantly lower than that in the control group( χ2= 5. 285,4. 200,P < 0. 05). After the treatment,the scores of SF-36 scale in the observation group were significantly higher than those in the control group( P < 0. 05). Conclusion: Modified Left Metal Decoction can significantly improve the vertigo symptoms of patients with kidney essence deficiency syndrome,and improve their quality of life.
Objective: To observe the influence of Modified Left Metal Decoction on clinical Efficacy and life quality of patients with vertigo with kidney essence deficiency syndrome. Methods: Seventy patients with vertigo with kidney essence deficiency syndrome admitted to our hospital from August 2013 to March 2018 were randomly divided into the control group and the observation group,with 35 cases in each group. The control group was treated with conventional Western medicine,while the observation group was treated with Left Metal Decoction on the basis of conventional Western medicine. The vertigo symptoms,clinical efficacy and quality of life of the two groups were observed. Results: After the treatment,the duration of vertigo in the observation group was significantly shorter than that in the control group( P < 0. 05),and the levels of basilar artery( BA),vertebrobasilar artery( VA),posterior cerebral artery( PCA) in the observation group were higher than those in the control group( t = 7. 091,2. 657,2. 408,2. 531,P < 0. 05). The effective rate in the observation group was 94. 29%,which was higher than that in the control group( 74. 29%,P < 0. 05). The incidence of adverse reactions in the observation group was 8. 57%,which was significantly lower than that in the control group( χ2= 5. 285,4. 200,P < 0. 05). After the treatment,the scores of SF-36 scale in the observation group were significantly higher than those in the control group( P < 0. 05). Conclusion: Modified Left Metal Decoction can significantly improve the vertigo symptoms of patients with kidney essence deficiency syndrome,and improve their quality of life.
引文
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[14]袁庆,程秀琴,李江,等.偏头痛与眩晕、耳鸣、听力下降[J].中华耳科学杂志,2014,12(2):242-245.
[15]郭震浪,王俊月,苏振宁,等.小柴胡汤治疗中风后眩晕的Meta分析[J].中国实验方剂学杂志,2015,21(24):214-218.
[16]陈莉,鲁应佳.丹参川芎嗪注射液治疗肺原性心脏病合并椎-基底动脉供血不足性眩晕临床研究[J].河南中医,2016,36(4):611-613.
[2] WUEHR M,BRANDT T,SCHNIEPP R. Distracting attention in phobic postural vertigo normalizes leg muscle activity and balance[J]. Neurology,2017,88(3):284.
[3]刘秋燕,吕光耀,张春兰,等.天麻钩藤饮及其加减治疗眩晕的系统评价[J].世界科学技术-中医药现代化,2014,16(2):239-248.
[4]刘红梅,李涛.中医临床研究中眩晕疗效评价方法的思考[J].中国中西医结合杂志,2014,34(10):1256-1259.
[5] DE S A,KULAMARVA G,CITRARO L,et al. Spontaneous nystagmus in benign paroxysmal positional vertigo[J]. American Journal of Otolaryngology,2017,32(3):185-189.
[6]邵义泽,王会民,赵文莉.中西医结合优化治疗眩晕的临床观察[J].中草药,2014,45(7):982-984.
[7]刘旭东,何庆勇,吴海芳,等.汉代以来著名医家治疗眩晕方剂用药规律的数据挖掘研究[J].北京中医药大学学报,2016,39(11):920-925.
[8] LEE S U,CHOI J Y,KIM H J,et al. Recurrent spontaneous vertigo with interictal headshaking nystagmus[J]. Neurology,2018,12(4):906-907.
[9]候转转,许世兵,邬伟刚,等.“通督疗法”治疗气血亏虚型颈性眩晕:随机对照研究[J].中国针灸,2016,36(9):901-905.
[10]修世国,邢东升,胡玮,等.眩晕障碍量表在BPPV患者生活质量评估中的应用[J].听力学及言语疾病杂志,2014,22(1):48-52.
[11]李永凯.天麻素辅助针灸治疗颈性眩晕疗效及对血浆ET-1和CGRP水平的影响[J].中国实验方剂学杂志,2015,21(12):162-165.
[12]张永斌,孙勍,彭新,等.老年特发性良性阵发性位置性眩晕的复位治疗及其疗效的研究[J].中华耳科学杂志,2015,12(2):282-287.
[13]贺思,赵晓峰,文妍,等.不同针刺手法治疗后循环缺血性眩晕患者120例随机双盲对照试验[J].中医杂志,2015,56(6):478-482.
[14]袁庆,程秀琴,李江,等.偏头痛与眩晕、耳鸣、听力下降[J].中华耳科学杂志,2014,12(2):242-245.
[15]郭震浪,王俊月,苏振宁,等.小柴胡汤治疗中风后眩晕的Meta分析[J].中国实验方剂学杂志,2015,21(24):214-218.
[16]陈莉,鲁应佳.丹参川芎嗪注射液治疗肺原性心脏病合并椎-基底动脉供血不足性眩晕临床研究[J].河南中医,2016,36(4):611-613.