摘要
目的探讨使用电子灸时采取不同温度对阿片类药物相关性便秘(OIC)的影响。方法将发生OIC的86例恶性肿瘤患者采用数字表法随机分为对照组28例、试验Ⅰ组29例、试验Ⅱ组29例。3组均采用常规治疗护理方案,试验Ⅰ组、试验Ⅱ组在对照组基础上分别予电子灸治疗,试验Ⅰ组电子灸温度为45℃,试验Ⅱ组电子灸温度为50℃,观察3组患者的便秘严重程度情况及治疗效果。结果对照组、试验Ⅰ组、试验Ⅱ组的便秘严重程度差异有统计学意义(P <0. 05);试验Ⅱ组的治疗有效率(86. 21%)和试验Ⅰ组的治疗有效率(82. 76%)显著优于对照组(71. 43%)(P <0. 05)。结论电子灸采用50℃的温度对OIC的治疗效果更显著。
Objective To investigate the effects of electronic moxibustion in different temperatures on opioid-related constipation( OIC). Methods Eighty-six malignant tumors patients with OIC were randomly divided into control group( n = 28),experimental group Ⅰ( n = 29),and experimental group Ⅱ( n = 29). The patients in three groups were treated with conventional treatment and nursing. The experimental groups Ⅰand Ⅱ were additionally treated with electronic moxibustion at45 ℃,50 ℃,respectively,on the basis of the control group. The patient's constipation severity and treatment effect were compared. Results There were significant differences in the severity of constipation in three groups( P < 0. 05). The treatment efficiency of the experimental group Ⅱ was86. 21%,and 82. 76% in the experimental group Ⅰ,which wereboth higher than that of the control group( P < 0. 05). Conclusion The use of electronic moxibustion at 50 ℃ is more effective in treating OIC.
引文
[1] Thomas J. Opioid-induced bowel dysfunction[J]. J Pain Symptom Manage,2008,35(1):103-113.
[2]葛英姿,黎蓉.电子灸防治阿片类相关性便秘的疗效观察[J].实用临床医药杂志,2016,20(24):142-143.
[3]杨旭明,汤家铭.一种模拟传统艾灸电子温灸仪的研制:应用安全及环保效应[J].中国组织工程研究,2016,20(42):6337-6342.
[4] Camilleri M,Drossman D A,Becker G,et al. Emerging treatments in neurogastroenterology:a multidisciplinary working group consensus statement on opioid-induced constipation[J].Neurogastroenterol Motil,2014,26(10):1386-1395.
[5]杨丽华,段培蓓,侯庆梅,等.肠功能量表在阿片相关性便秘人群中应用的信效度测评[J].中国实用护理杂志,2013,29(17):28-30.
[6] Poulsen J L,Brock C,Olesen A E,et al. Clinical potential of naloxegol in the management of opioid-induced bowel dysfunction[J]. Clin Exp Gastroenterol,2014,7:345-358.
[7]刘月,郭小川,符文彬,等.灸法治疗便秘临床疗效的系统评价[C].中华中医药学会第五次科技成果峰会暨2015年度科技成果、优秀人才奖励大会论文集,2015:53-58.
[8]杨宗城.烧伤治疗学[M].第3版.北京:人民卫生出版社,2006:120-123.