养心汤联合穴位贴敷治疗稳定型心绞痛临床研究
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摘要
目的观察养心汤联合穴位贴敷治疗稳定型心绞痛(气虚血瘀证)的临床疗效并探讨其作用机制。方法患者64例随机分为两组,对照组采用常规西药治疗,治疗组在对照组基础上,联合应用养心汤加减方和穴位贴敷,评定临床疗效。结果治疗后两组中医证候积分、心绞痛发作次数均低于治疗前(P <0.05),且治疗组均低于对照组(P<0.05)。治疗组心绞痛总有效率为93.75%,高于对照组之78.13%(P <0.05)。治疗后两组视觉模拟量表(VAS)评分均低于治疗前(P <0.05),但是治疗组与对照组差异无统计学意义(P> 0.05)。结论养心汤加减方联合穴位贴敷治疗稳定型心绞痛(气虚血瘀证)疗效显著,安全性高,效果优于单纯西药常规治疗。
Objective: To observe the clinical effects of Yangxin Decoction and point application therapy on patients with angina pectoris of Qi deficiency and blood stasis syndrome. Methods: 64 patients were randomly divided into the control group(32 cases) and the treatment group(32 cases). The control group was given conventional Western medicine symptomatic treatment. The treatment group was given the combination treatment of Yangxin Decoction and point application therapy. The clinical efficiency was evaluated. Results: After treatment,the scores of TCM symptoms and the number of angina attacks in both groups were lower than those indices before treatment(P < 0.05),and the treatment group was lower than the control group(P < 0.05). The total effective rate of the treatment group was 93.75%,which was higher than 78.13% in the control group(P < 0.05). After treatment,the VAS scores of both groups were lower than those before treatment(P < 0.05),but there was no significant difference between the two groups(P > 0.05). Conclusion: Yangxin Decoction plus point application on stable angina pectoris has a remarkable curative effect,with high safety and superior effect to conventional Western medicine.
Objective: To observe the clinical effects of Yangxin Decoction and point application therapy on patients with angina pectoris of Qi deficiency and blood stasis syndrome. Methods: 64 patients were randomly divided into the control group(32 cases) and the treatment group(32 cases). The control group was given conventional Western medicine symptomatic treatment. The treatment group was given the combination treatment of Yangxin Decoction and point application therapy. The clinical efficiency was evaluated. Results: After treatment,the scores of TCM symptoms and the number of angina attacks in both groups were lower than those indices before treatment(P < 0.05),and the treatment group was lower than the control group(P < 0.05). The total effective rate of the treatment group was 93.75%,which was higher than 78.13% in the control group(P < 0.05). After treatment,the VAS scores of both groups were lower than those before treatment(P < 0.05),but there was no significant difference between the two groups(P > 0.05). Conclusion: Yangxin Decoction plus point application on stable angina pectoris has a remarkable curative effect,with high safety and superior effect to conventional Western medicine.
引文
[1]丁怀兰,王晓玲.通心络胶囊治疗冠心病稳定型心绞痛30例[J].实用中医内科杂志,2004,18(1):67-67.
[2]陈伟伟,高润林,刘力生,等.2015年中国心血管病报告[J].中国循环杂志社,2016,31(6):521-528.
[3]冷德生,高恩宇,李富震,等.中医药治疗冠心病心绞痛的研究进展[J].中医药信息,2017,34(4):119-123.
[4]高润霖.慢性稳定型心绞痛诊断与治疗指南[J].中华心血管病杂志,2007,35(3):195-206.
[5]中华人民共和国卫生部.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002:68-73.
[6]Huskisson EC.Mesurement of pain[J].Lancet,1974,27(12):1127.
[7]罗辉,廖星,王茜.中医证候积分在疗效评价中的应用:基于240项随机对照试验的比较研究[J].中国中西医结合杂志,2015,35(10):1261-1266.
[8]孙传兴.临床疾病诊断依据治愈好转标准[M].2版.北京:人民军医出版社,2006:15.
[9]曹卉娟,邢建民,刘建平.视觉模拟评分法在症状类结局评价测量中的应用[J].中医杂志,2009,50(7):600-602.
[10]吴佳佳.参麦注射液治疗冠心病心绞痛的临床应用[J].浙江中西医结合杂志,2010,20(8):527-528.
[11]赵永法,马丽娜,皇甫海全,等.周亚滨教授治疗稳定型心绞痛经验[J].浙江中医药大学学报,2017,41(7):580-581.
[12]王义强,邓悦,于金娜,等.冠心病中医病因、病机及诊治的古代文献回顾[J].环球中医药,2013,6(4):297-300.
[13]刘西建,韩涛.中药穴位贴敷研究现状及思路[J].中医药信息,2014,31(5):130-132.
[14]张琪,周亚滨,孙静.养心颗粒治疗心血管疾病的研究进展[J].中西医结合心脑血管病杂志,2015,13(14):1634-1636.
[15]于海睿,皇甫海全,孙静,等.养心汤的药理研究进展及临床应用概况[J].中国中医急症,2014,23(3):480-482.
[16]司丹丹,顾正荣,徐伟,等.黄芪提取液纳滤浓缩的实验研究[J].中成药,2007,29(12):1854-1857.
[17]杨式友.活血化瘀药药理与应用[J].时珍国药研究,1997,8(5):43.
[2]陈伟伟,高润林,刘力生,等.2015年中国心血管病报告[J].中国循环杂志社,2016,31(6):521-528.
[3]冷德生,高恩宇,李富震,等.中医药治疗冠心病心绞痛的研究进展[J].中医药信息,2017,34(4):119-123.
[4]高润霖.慢性稳定型心绞痛诊断与治疗指南[J].中华心血管病杂志,2007,35(3):195-206.
[5]中华人民共和国卫生部.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002:68-73.
[6]Huskisson EC.Mesurement of pain[J].Lancet,1974,27(12):1127.
[7]罗辉,廖星,王茜.中医证候积分在疗效评价中的应用:基于240项随机对照试验的比较研究[J].中国中西医结合杂志,2015,35(10):1261-1266.
[8]孙传兴.临床疾病诊断依据治愈好转标准[M].2版.北京:人民军医出版社,2006:15.
[9]曹卉娟,邢建民,刘建平.视觉模拟评分法在症状类结局评价测量中的应用[J].中医杂志,2009,50(7):600-602.
[10]吴佳佳.参麦注射液治疗冠心病心绞痛的临床应用[J].浙江中西医结合杂志,2010,20(8):527-528.
[11]赵永法,马丽娜,皇甫海全,等.周亚滨教授治疗稳定型心绞痛经验[J].浙江中医药大学学报,2017,41(7):580-581.
[12]王义强,邓悦,于金娜,等.冠心病中医病因、病机及诊治的古代文献回顾[J].环球中医药,2013,6(4):297-300.
[13]刘西建,韩涛.中药穴位贴敷研究现状及思路[J].中医药信息,2014,31(5):130-132.
[14]张琪,周亚滨,孙静.养心颗粒治疗心血管疾病的研究进展[J].中西医结合心脑血管病杂志,2015,13(14):1634-1636.
[15]于海睿,皇甫海全,孙静,等.养心汤的药理研究进展及临床应用概况[J].中国中医急症,2014,23(3):480-482.
[16]司丹丹,顾正荣,徐伟,等.黄芪提取液纳滤浓缩的实验研究[J].中成药,2007,29(12):1854-1857.
[17]杨式友.活血化瘀药药理与应用[J].时珍国药研究,1997,8(5):43.