MRI T_2-Mapping成像对膝关节髌软骨早期退变的诊断价值
|
摘要
目的:探讨MRI T_2-Mapping成像对膝关节髌软骨早期退变的影像诊断价值。方法:采用GE Discovery 750 3.0 T MRI 8回波SE序列行髌骨轴位T_2-Mapping成像。采用国际软骨修复协会(ICRS)标准对髌软骨进行分级,并与关节镜下所见软骨对照,测量正常组和膝关节骨关节炎(OA)组的髌软骨最厚处和病变处的平均T_2值。结果:正常组膝关节软骨表面光滑、完整、信号均匀,伪彩图呈红色;OA组软骨连续性可,软骨层变薄,局部信号不均匀,伪彩图呈斑片状蓝绿色。早期OA组平均T_2值高于正常组(P<0.05)。结论:T_2-Mapping成像对膝关节髌软骨早期退变有很高的价值。
Objective:To investigate the diagnostic value of MRI T_2-Mapping imaging in the early stage of knee degenerative cartilage degeneration.Methods:The tibial axial T_2-Mapping imaging was underwent.Cartilage degeneration were graded using the ICRS criteria,compared with cartilage seen under arthroscopy,the T_2value at the thickest part of the cartilage of the OA group and the normal group were measured.Results:In the normal group,the articular cartilage of subjects showed homogeneous signal with the smooth and complete surface and their color maps were red.In the OA group,the articular cartilage of subjects showed heterogeneous signal with acceptable continuity and thin thickness and their color maps were spot-liked cyan.Average T_2values of the OA group were bigger than those of the normal group(P<0.05).Conclusion:T_2-Mapping imaging has a high clinical value in the early diagnosis of cartilage degeneration of the knee joint.
Objective:To investigate the diagnostic value of MRI T_2-Mapping imaging in the early stage of knee degenerative cartilage degeneration.Methods:The tibial axial T_2-Mapping imaging was underwent.Cartilage degeneration were graded using the ICRS criteria,compared with cartilage seen under arthroscopy,the T_2value at the thickest part of the cartilage of the OA group and the normal group were measured.Results:In the normal group,the articular cartilage of subjects showed homogeneous signal with the smooth and complete surface and their color maps were red.In the OA group,the articular cartilage of subjects showed heterogeneous signal with acceptable continuity and thin thickness and their color maps were spot-liked cyan.Average T_2values of the OA group were bigger than those of the normal group(P<0.05).Conclusion:T_2-Mapping imaging has a high clinical value in the early diagnosis of cartilage degeneration of the knee joint.
引文
[1] Mosher TJ,Dardzinski BJ. Cartilage MRI T2relaxation time mapping:overing and applications[J]. Semin Musculoskelet Radiol,2004,8:355-368.
[2]任阿红,郑卓肇.髌软骨T2-mapping成像:MRI正常与退变软骨的差异[J].中国医学影像技术,2011,27(10):2113-2117.
[3]任阿红,郑卓肇.经关节镜证实的正常髌软骨T2值空间分布特征[J].中国医学影像学杂志,2012,20(7):503-507.
[4] Brittberg M,Peterson L. Introduction of an articular cartilage classification[J]. ICRS Newsletter,1998,1:5.
[5]郑红伟,李小明,罗敏,等. MR T2-mapping成像对诊断早期膝关节软骨损伤的临床应用价值[J].医学影像学杂志,2008,18(5):532-534.
[6]陈其春,邹月芬,王德杭,等.磁共振T2-mapping成像在膝关节早期骨性关节炎中的应用[J].临床放射学杂志,2012,31(1):81-85.
[7]王平,黄刚,张文文,等.应用磁共振T2-mapping成像评价非专业马拉松运动员膝关节软骨改变[J].中国临床医学影像杂志,2014,25(12):877-881.
[8] Nieminen MT,Toyras J,Rieppo J,et al. Quantitative M R microscopy of enzymatically degraded articular cartilage[J]. Magn Reson Med,2015,43:676-681.
[9] Nieminen MT,Rieppo J,Toyras J,et al. T2relaxation reveals spatial collagen architecture in articular cartilage:a comparative quantitative MRI and polarized light microscopic study[J]. Magn Reson Med,2001,46:487-493.
[10] Xia Y. Magic-angle effect in magnetic resonance imaging of articular cartilage:a review[J]. Invest Radiol,2000,35:602-621.
[11] Keinan-Adamsky K,Shinar H,Navon G. Multinuclear NMR and MRI studies of the maturation of pig articular cartilage[J]. Magn Reson Med,2010,55:532-540.
[12]李晓芬. 3.0 T MR T2-mapping对早期膝关节软骨损伤的临床应用价值[D].南昌:南昌大学,2015.
[13]陶娟.比较四种3D-MR序列在膝关节软骨和骨关节炎病变软骨的应用价值[D].武汉:华中科技大学,2014.
[14] Mosher TJ,Dardzinski BJ,Smith MB. Human articular cartilage:influence of aging and early symptomatic degeneration on the spatial variation of T2--preliminary findings at 3 T[J]. Radiology,2000,214:259-266.
[15]王鹤翔,郝大鹏,徐文坚,等. 3.0 T MRI T2-mapping对膝关节软骨退变的评估价值[J].磁共振成像,2012,3(4):245-249.
[16] Bining HJ,Santos R,Andrews G,et al. Can T2relaxation values and color maps be used to detect chondral damage utilizing subchondral bone marrow edema as a marker[J]. Skeletal Radiol,2009,38:459-465.
[17] Li X,Benjamin MC,Link TM,et al. In vivo T(1rho)and T(2)mapping of articular cartilage in osteoarthritis of the knee using 3T MRI[J]. Osteoarthritis Cartilage,2007,15:789-797.
[2]任阿红,郑卓肇.髌软骨T2-mapping成像:MRI正常与退变软骨的差异[J].中国医学影像技术,2011,27(10):2113-2117.
[3]任阿红,郑卓肇.经关节镜证实的正常髌软骨T2值空间分布特征[J].中国医学影像学杂志,2012,20(7):503-507.
[4] Brittberg M,Peterson L. Introduction of an articular cartilage classification[J]. ICRS Newsletter,1998,1:5.
[5]郑红伟,李小明,罗敏,等. MR T2-mapping成像对诊断早期膝关节软骨损伤的临床应用价值[J].医学影像学杂志,2008,18(5):532-534.
[6]陈其春,邹月芬,王德杭,等.磁共振T2-mapping成像在膝关节早期骨性关节炎中的应用[J].临床放射学杂志,2012,31(1):81-85.
[7]王平,黄刚,张文文,等.应用磁共振T2-mapping成像评价非专业马拉松运动员膝关节软骨改变[J].中国临床医学影像杂志,2014,25(12):877-881.
[8] Nieminen MT,Toyras J,Rieppo J,et al. Quantitative M R microscopy of enzymatically degraded articular cartilage[J]. Magn Reson Med,2015,43:676-681.
[9] Nieminen MT,Rieppo J,Toyras J,et al. T2relaxation reveals spatial collagen architecture in articular cartilage:a comparative quantitative MRI and polarized light microscopic study[J]. Magn Reson Med,2001,46:487-493.
[10] Xia Y. Magic-angle effect in magnetic resonance imaging of articular cartilage:a review[J]. Invest Radiol,2000,35:602-621.
[11] Keinan-Adamsky K,Shinar H,Navon G. Multinuclear NMR and MRI studies of the maturation of pig articular cartilage[J]. Magn Reson Med,2010,55:532-540.
[12]李晓芬. 3.0 T MR T2-mapping对早期膝关节软骨损伤的临床应用价值[D].南昌:南昌大学,2015.
[13]陶娟.比较四种3D-MR序列在膝关节软骨和骨关节炎病变软骨的应用价值[D].武汉:华中科技大学,2014.
[14] Mosher TJ,Dardzinski BJ,Smith MB. Human articular cartilage:influence of aging and early symptomatic degeneration on the spatial variation of T2--preliminary findings at 3 T[J]. Radiology,2000,214:259-266.
[15]王鹤翔,郝大鹏,徐文坚,等. 3.0 T MRI T2-mapping对膝关节软骨退变的评估价值[J].磁共振成像,2012,3(4):245-249.
[16] Bining HJ,Santos R,Andrews G,et al. Can T2relaxation values and color maps be used to detect chondral damage utilizing subchondral bone marrow edema as a marker[J]. Skeletal Radiol,2009,38:459-465.
[17] Li X,Benjamin MC,Link TM,et al. In vivo T(1rho)and T(2)mapping of articular cartilage in osteoarthritis of the knee using 3T MRI[J]. Osteoarthritis Cartilage,2007,15:789-797.