动脉内灌注盐酸替罗非班处理支架辅助弹簧圈栓塞颅内动脉瘤时术中急性血栓的有效性探讨
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摘要
目的探讨动脉内灌注盐酸替罗非班在处理支架辅助弹簧圈栓塞颅内动脉瘤时术中急性血栓的有效性。方法选择我院2016年5月—2018年5月接收的16例应用支架辅助弹簧圈栓塞颅内动脉瘤时发生术中急性血栓患者,探讨动脉内灌注盐酸替罗非班处理的效果。结果患者经盐酸替罗非班治疗后均表现出良好的疗效,颅内急性血栓部位血管得以打通,且颅内再无出血情况;术后患者无植物生存状态或死亡,13例患者恢复良好,占比81.25%。结论临床上使用动脉内灌注盐酸替罗非班处理支架辅助弹簧圈栓塞颅内动脉瘤时术中急性血栓的疗效较好,有效降低了术后并发症,提高患者术后生存质量,值得推广。
Objective To investigate the efficacy of intravascular infusion of tirofiban hydrochloride in the treatment of intracranial aneurysms with stent-assisted coil embolization. Methods Sixteen cases of patients with acute thrombosis during the operation of stent-assisted coil embolization for intracranial aneurysm received by the inpatient department of our hospital from May 2016 to May 2018 were selected to analyze their efficacy. Results All the patients showed good clinical efficacy after treatment with tirofiban hydrochloride,and the blood vessels of the acute cerebral thrombosis site were opened,and there was no hemorrhage. There was no vegetative state or death after the operation,and 13 patients recovered well,accounting for up to 81.25%. Conclusion The clinical application of intravascular infusion of tirofiban hydrochloride in the treatment of intracranial aneurysms with stent-assisted coil embolization has good timeliness,effectively reducing the postoperative complications and improving the postoperative quality of life of patients. It is worthy of clinical use.
Objective To investigate the efficacy of intravascular infusion of tirofiban hydrochloride in the treatment of intracranial aneurysms with stent-assisted coil embolization. Methods Sixteen cases of patients with acute thrombosis during the operation of stent-assisted coil embolization for intracranial aneurysm received by the inpatient department of our hospital from May 2016 to May 2018 were selected to analyze their efficacy. Results All the patients showed good clinical efficacy after treatment with tirofiban hydrochloride,and the blood vessels of the acute cerebral thrombosis site were opened,and there was no hemorrhage. There was no vegetative state or death after the operation,and 13 patients recovered well,accounting for up to 81.25%. Conclusion The clinical application of intravascular infusion of tirofiban hydrochloride in the treatment of intracranial aneurysms with stent-assisted coil embolization has good timeliness,effectively reducing the postoperative complications and improving the postoperative quality of life of patients. It is worthy of clinical use.
引文
[1]陆新宇,李巧玉,陈波.替罗非班治疗支架辅助弹簧圈栓塞动脉瘤术中急性血栓形成[J].国际神经病学神经外科学杂志,2018,45(1):22-24.
[2]周江,周溱,许泽武.支架辅助弹簧圈栓塞颅内复杂动脉瘤的临床研究[J].中国医师杂志,2015,17(6):938-940.
[3]袁喜平,冯巍,赵旭明.支架辅助弹簧圈栓塞颅内宽颈动脉瘤所致并发症的诊治体会[J].中国实验诊断学,2015,56(4):670-671.
[4]金二亮,祝源,杨李,等.替罗非班在颅内动脉瘤支架辅助栓塞术中抗血小板聚集的临床研究[J].中华神经外科杂志,2017,33(4):18-20.
[5]祝源,李俊,杨铭,等.支架辅助弹簧圈栓塞颅内动脉瘤抗血小板聚集的治疗方案[J].中华神经外科杂志,2017,33(7):9-12.
[6]梁晓东,王子亮,李天晓,等.盐酸替罗非班在颅内动脉瘤介入治疗中的应用进展[J/CD].中华介入放射学电子杂志,2016,4(1):44-47.
[2]周江,周溱,许泽武.支架辅助弹簧圈栓塞颅内复杂动脉瘤的临床研究[J].中国医师杂志,2015,17(6):938-940.
[3]袁喜平,冯巍,赵旭明.支架辅助弹簧圈栓塞颅内宽颈动脉瘤所致并发症的诊治体会[J].中国实验诊断学,2015,56(4):670-671.
[4]金二亮,祝源,杨李,等.替罗非班在颅内动脉瘤支架辅助栓塞术中抗血小板聚集的临床研究[J].中华神经外科杂志,2017,33(4):18-20.
[5]祝源,李俊,杨铭,等.支架辅助弹簧圈栓塞颅内动脉瘤抗血小板聚集的治疗方案[J].中华神经外科杂志,2017,33(7):9-12.
[6]梁晓东,王子亮,李天晓,等.盐酸替罗非班在颅内动脉瘤介入治疗中的应用进展[J/CD].中华介入放射学电子杂志,2016,4(1):44-47.