OCTA下硅油填充术后视盘血流密度变化分析
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摘要
目的分析光相干断层扫描血管成像(OCTA)下硅油填充术后视盘血流密度的变化。方法选取我院2018年1月至2018年10月行玻璃体切除联合硅油填充术的孔源性视网膜脱离患者20例作为观察组,另选取同期健康体检者20例作为对照组。使用OCTA检测观察组填充前,填充1周、 1个月及3个月后的视盘周围毛细血管血流密度、视盘血流密度、盘内毛细血流密度,并与对照组进行对比。结果观察组填充前后的视盘周围毛细血管血流密度、视盘血流密度、盘内毛细血管血流密度均显著低于对照组(P <0.05)。观察组填充前后的上述指标比较差异均无统计学意义(P>0.05)。结论硅油眼内填充3个月并未明显改变视盘血流密度。
Objective To analyze the changes of optic disc blood flow density after silicone oil filling under optical coherence tomography angiography(OCTA). Methods 20 cases of patients with rhegmatogenous retinal detachment undergoing vitrectomy combined with silicone oil filling in our hospital from January 2018 to October 2018 were selected as observation group, and another 20 people with healthy physical examination at the same period were selected as control group. The peripapillary capillary blood flow density, optic disc blood flow density and inner optic disc capillary blood flow density before filling, 1 week after filling, 1 month after filling and 3 months after filling were detected by OCTA, which were compared with the control group. Results The peripapillary capillary blood flow density,optic disc blood flow density and inner optic disc capillary blood flow density before and after filling of observation group were significantly lower than those of control group(P <0.05). No statistical difference was found in the above indicators before and after filling in observation group(P >0.05). Conclusions The optic disc blood flow density does not change significantly 3 months after silicone oil filling.
Objective To analyze the changes of optic disc blood flow density after silicone oil filling under optical coherence tomography angiography(OCTA). Methods 20 cases of patients with rhegmatogenous retinal detachment undergoing vitrectomy combined with silicone oil filling in our hospital from January 2018 to October 2018 were selected as observation group, and another 20 people with healthy physical examination at the same period were selected as control group. The peripapillary capillary blood flow density, optic disc blood flow density and inner optic disc capillary blood flow density before filling, 1 week after filling, 1 month after filling and 3 months after filling were detected by OCTA, which were compared with the control group. Results The peripapillary capillary blood flow density,optic disc blood flow density and inner optic disc capillary blood flow density before and after filling of observation group were significantly lower than those of control group(P <0.05). No statistical difference was found in the above indicators before and after filling in observation group(P >0.05). Conclusions The optic disc blood flow density does not change significantly 3 months after silicone oil filling.
引文
[1]李军,李思媛,郑秀丽,等.玻璃体切割并晶状体切除硅油填充术治疗重度外源性眼内炎[J].中国实用眼科杂志, 2015, 33(3):279-282.
[2] Jonas JB, Knorr HL, Rank RM, et al. Intraocular pressure and silicone oil endotamponade[J]. J Glaucoma, 2001, 10(2):102.
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[5]王敏.利用光相干断层扫描血管成像技术优势,提升视网膜脉络膜血管疾病认知水平[J].中华眼底病杂志, 2016, 32(4):353-356.
[6]李林,李琦琰,庞秀琴.重硅油Densiron 68眼内填充治疗外伤性视网膜脱离的疗效与并发症[J].眼科, 2012, 21(4):252-256.
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[8]王爽,崔浩,赵艳霞.重硅油在玻璃体视网膜疾病手术中的应用[J].国际眼科杂志, 2017, 17(6):1178-1180.
[9] Jia Y, Wei E, Wang X, et al. Optical coherence tomography angiography of optic disc perfusion in glaucoma[J]. Ophthalmology, 2014,121(7):1322-1332.
[10]黎晓新,石璇.认识光相干断层扫描血管成像技术特色,提升光相干断层扫描血管成像技术临床应用水平[J].中华眼底病杂志,2017, 33(1):3-6.
[11]李强,孙力,陈诗兰.重硅油填充在下方裂孔的视网膜脱离术中应用[J].中华眼外伤职业眼病杂志, 2012, 34(7):521-523.
[12]胡富生,钱爱军.糖尿病与高眼压及原发性开角型青光眼的相关性探讨[J].海南医学, 2011, 22(4):93-94.
[13] HollóG. Vessel density calculated from OCT angiography in 3 peripapillary sectors in normal, ocular hypertensive, and glaucoma eyes[J]. Eur J Ophthalmol, 2016, 26(3):e42-45.
[2] Jonas JB, Knorr HL, Rank RM, et al. Intraocular pressure and silicone oil endotamponade[J]. J Glaucoma, 2001, 10(2):102.
[3]陈小春,李维娜,李超,等.硅油填充术后继发性青光眼的临床研究[J].国际眼科杂志, 2013, 13(12):2507-2509.
[4]董秀芬,钟华.相干光断层血管成像在青光眼视盘血流检测中的应用[J].国际眼科纵览, 2016, 40(3):145-150.
[5]王敏.利用光相干断层扫描血管成像技术优势,提升视网膜脉络膜血管疾病认知水平[J].中华眼底病杂志, 2016, 32(4):353-356.
[6]李林,李琦琰,庞秀琴.重硅油Densiron 68眼内填充治疗外伤性视网膜脱离的疗效与并发症[J].眼科, 2012, 21(4):252-256.
[7]曲申,荣翱.重硅油在复杂性视网膜脱离手术中的应用[J].中华眼外伤职业眼病杂志, 2012, 34(3):238-240.
[8]王爽,崔浩,赵艳霞.重硅油在玻璃体视网膜疾病手术中的应用[J].国际眼科杂志, 2017, 17(6):1178-1180.
[9] Jia Y, Wei E, Wang X, et al. Optical coherence tomography angiography of optic disc perfusion in glaucoma[J]. Ophthalmology, 2014,121(7):1322-1332.
[10]黎晓新,石璇.认识光相干断层扫描血管成像技术特色,提升光相干断层扫描血管成像技术临床应用水平[J].中华眼底病杂志,2017, 33(1):3-6.
[11]李强,孙力,陈诗兰.重硅油填充在下方裂孔的视网膜脱离术中应用[J].中华眼外伤职业眼病杂志, 2012, 34(7):521-523.
[12]胡富生,钱爱军.糖尿病与高眼压及原发性开角型青光眼的相关性探讨[J].海南医学, 2011, 22(4):93-94.
[13] HollóG. Vessel density calculated from OCT angiography in 3 peripapillary sectors in normal, ocular hypertensive, and glaucoma eyes[J]. Eur J Ophthalmol, 2016, 26(3):e42-45.