氨基化碳纳米管在神经修复作用中的研究进展
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  • 英文篇名:Research Progress on Aminated Carbon Nanotubes in Nerve Repair
  • 作者:周红燕 ; 滕希 ; 李晓娟 ; 郭亚可
  • 英文作者:ZHOU Hong-yan;TENG Xi;LI Xiao-juan;GUO Ya-ke;The First Affiliated Hospital of Medical College of Shihezi University of Xinjiang;First Jikun Hospital of Xinjiang Uygur Autonomous Region;School of Pharmacy,Medical College,Shihezi University;
  • 关键词:氨基化碳纳米管 ; 神经修复 ; 聚酰胺-胺 ; 聚乙烯亚胺
  • 英文关键词:aminated carbon nanotubes;;nerve repair;;polyamide amine;;polyethyleneimine
  • 中文刊名:GZHA
  • 英文刊名:Guangzhou Chemical Industry
  • 机构:石河子大学医学院第一附属医院药剂科;新疆维吾尔自治区第一济困医院;石河子大学;
  • 出版日期:2018-04-23
  • 出版单位:广州化工
  • 年:2018
  • 期:v.46
  • 语种:中文;
  • 页:GZHA201808008
  • 页数:3
  • CN:08
  • ISSN:44-1228/TQ
  • 分类号:20-22
摘要
超支化聚合物为碳纳米管的功能化研究提供了一种新方法,功能化的碳纳米管具有良好的分散性和生物相容性,能有效携载药物或基因,为中枢神经系统疾病的治疗提供了新思路。氨基是一种常见的修饰基团,载体可以通过酰胺键方便地携带药物,因此碳纳米管表面氨基化具有广泛的应用前景。氨基化碳纳米管具有溶解性好、反应活性高和细胞毒性低等特点,为其在医药领域的应用奠定了基础。
        Hyperbranched polymers provide a new method for the functional study of carbon nanotubes.Functionalized carbon nanotubes have good dispersion and biocompatibility,so it can effectively carry drugs or genes and provide a new idea for the treatment of central nervous system diseases. Amino is an important modification group in biochemistry. Many drugs can be attached to the corresponding carrier through amide bond. Therefore,surface amination is one of the most important methods to build a practical carbon nanotube. Aminated carbon nanotubes have the characteristics of good solubility,high reactive activity and low cytotoxicity,which lay a foundation for its application in the field of medicine.
引文
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