按摩手法联合补气养阴通络方治疗糖尿病周围神经病变
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摘要
目的探讨按摩手法联合自拟补气养阴通络方治疗糖尿病周围神经病变的临床疗效。方法选取60例糖尿病周围神经病变患者作为研究对象,按照随机数字表的方法分为观察组和对照组,各30例。对照组采取常规干预方法治疗,观察组采取在常规治疗方法基础上,配合按摩手法联合自拟补气养阴通络方进行治疗,按摩患者的足三里、阴陵泉、三阴交、涌泉等穴位,40 min/次,并联合自拟补气养阴通络方配合治疗,穴位按摩和补气养阴通络方,1次/d。分别对患者的治疗前后震动感觉阈值、血糖指标、中医证候积分进行客观比较。结果观察组患者治疗后的震动感觉阈值各指标显著优于对照组,具有统计学意义(P <0.05),观察组患者治疗后血糖指标均优于对照组,具有统计学意义(P <0.05)。2组治疗后中医证候积分变化比较,差异具有统计学意义(P <0.05)。结论按摩手法联合自拟补气养阴通络方治疗糖尿病周围神经病变,能够有效降低患者的神经病变速率,进一步促进患者病情的恢复,具备推广优势。
Objective To explore the clinical effect of massage manipulation combined with self-made tonifying qi, nourishing yin and dredging collaterals on diabetic peripheral neuropathy. Methods 60 patients with diabetic peripheral neuropathy were selected as the research subjects. The patients were divided into the observation group and the control group according to the random number table. The routine intervention method was adopted to the control group. In the observation group, on the basis of the routine treatment method, combined with massage manipulation and self-madetonifying qi, nourishing yin and dredging collaterals decoction were used for the treatment group.Massage on the acupoints of Zusanli, Yinlingquan, Sanyinjiao and Yongquan, 40 minutes each time, combined with self-madetonifying qi, nourishing yin and dredging collaterals decoction once a day. Before and after treatment, the shock sensation threshold, blood glucose index and TCM syndrome integral were compared objectively. Results After comparison, the indexes of vibration sensation threshold of the patients in the observation group were significantly better than those in the control group, with statistical significance(P<0.05). The blood glucose indexes of the patients in the observation group were better than those in the control group, with statistical significance(P <0.05).In addition, there was significant difference in TCM syndrome integral data(P <0.05). Conclusion Massage manipulation combined withself-madetonifying qi, nourishing yin and dredging collaterals decoction in treating diabetic peripheral neuropathy can effectively reduce the rate of neuropathy, further promote the recovery of the patient's condition, and has the advantage of popularization.
Objective To explore the clinical effect of massage manipulation combined with self-made tonifying qi, nourishing yin and dredging collaterals on diabetic peripheral neuropathy. Methods 60 patients with diabetic peripheral neuropathy were selected as the research subjects. The patients were divided into the observation group and the control group according to the random number table. The routine intervention method was adopted to the control group. In the observation group, on the basis of the routine treatment method, combined with massage manipulation and self-madetonifying qi, nourishing yin and dredging collaterals decoction were used for the treatment group.Massage on the acupoints of Zusanli, Yinlingquan, Sanyinjiao and Yongquan, 40 minutes each time, combined with self-madetonifying qi, nourishing yin and dredging collaterals decoction once a day. Before and after treatment, the shock sensation threshold, blood glucose index and TCM syndrome integral were compared objectively. Results After comparison, the indexes of vibration sensation threshold of the patients in the observation group were significantly better than those in the control group, with statistical significance(P<0.05). The blood glucose indexes of the patients in the observation group were better than those in the control group, with statistical significance(P <0.05).In addition, there was significant difference in TCM syndrome integral data(P <0.05). Conclusion Massage manipulation combined withself-madetonifying qi, nourishing yin and dredging collaterals decoction in treating diabetic peripheral neuropathy can effectively reduce the rate of neuropathy, further promote the recovery of the patient's condition, and has the advantage of popularization.
引文
[1]李竞,张琳,赵湜.α-硫辛酸联合甲钴胺治疗糖尿病周围神经病变的Meta分析[J].中国医药导报,2013,10(3):88-90.
[2]陈丽,梁凤霞,陈瑞,等.“标本配穴”针灸结合甲钴胺治疗糖尿病周围神经病变的临床对照研究[J].中国中西医结合消化杂志,2014,22(4):178-181.
[3]赵立,马宇航,彭永德.α-硫辛酸治疗糖尿病周围神经病变的疗效观察[J].中国糖尿病杂志,2014,22(3):207-209.
[4]黄耀宁,韦洪江.α-硫辛酸联合甲钴胺治疗糖尿病周围神经病变的疗效及对氧化应激的影响[J].山东医药,201353(8):13-15.
[5]邹立华,李惠,陈小丹,等.甲钴胺联合α-硫辛酸、血府逐瘀胶囊治疗糖尿病周围神经病变疗效观察[J].中西医结合心脑血管病杂志,2014,12(3):269-270.
[6]HUR J,O'BRIEN P D,NAIR V,et al.Transcriptional networks of murine diabetic peripheral neuropathy and nephropathy common and distinc t gene expression patterns[J]Diabetologia,2016,59(6):1297-1306.
[7]HEWSTON P,DESHPANDE N.Falls and balance impairments in older adults with type 2 diabetes:thinking beyond diabetic peripheral neuropathy[J].Canadian Journal of Diabetes,201640(1):6-9.
[8]吴小芬,罗晓红,徐进,等.木丹颗粒联合甲钴胺及α-硫辛酸治疗糖尿病周围神经病变的疗效观察[J].中华全科医学,2015,13(12):1966-1967.
[9]张永文,韩康生,程燕.糖尿病周围神经病变的中医病因病机及证治[J].吉林中医药,2014,34(6):561-564.
[10]苏玉珂.中医药治疗糖尿病周围神经病变的Meta分析[J]天津中医药,2014,31(6):335-339.
[11]孙朦朦,陈惠,倪青.糖尿病周围神经病变病证结合研究现状及思路探讨[J].长春中医药大学学报,2013,29(2)240-241.
[12]张宏,刘美奇,王旭昀,等.200例糖尿病周围神经病变患者中医证候调查分析[J].长春中医药大学学报,201531(1):99-101.
[13]侯荣.中药穴位敷贴联合中药汤剂治疗糖尿病周围神经病变的临床观察[J].现代中西医结合杂志,2016,25(14)1518-1520.
[14]徐之也.中药汤剂治疗糖尿病周围神经病变临床疗效的Meta分析[D].沈阳:辽宁中医药大学,2013.
[15]吕璐,陆灏.中医内、外治法防治糖尿病周围神经病变研究进展[J].世界临床药物,2017,38(9):593-596.
[16]徐融,杨聘,徐精彩.中医综合疗法治疗糖尿病周围神经病变临床观察[J].中华中医药学刊,2014,32(4):860-862.
[17]袁艺,肖丹,赵波.中医药综合治疗糖尿病周围神经病变临床研究[J].中医学报,2014,29(8):1122-1124.
[18]曹柏龙,苗桂珍,韩文兵,等.火针疗法联合中药改善糖尿病周围神经病变患者临床症状评分疗效观察[J].北京中医药,2014,33(5):380-382.
[19]倪志萍.中药熏洗配合穴位按摩治疗糖尿病周围神经病变疗效观察[J].现代中西医结合杂志,2014,23(34):3797-3799.
[20]白清.黄芪桂枝五物汤对糖尿病周围神经病变的疗效及神经传导速度的影响[J].中成药,2015,37(5):962-964.
[2]陈丽,梁凤霞,陈瑞,等.“标本配穴”针灸结合甲钴胺治疗糖尿病周围神经病变的临床对照研究[J].中国中西医结合消化杂志,2014,22(4):178-181.
[3]赵立,马宇航,彭永德.α-硫辛酸治疗糖尿病周围神经病变的疗效观察[J].中国糖尿病杂志,2014,22(3):207-209.
[4]黄耀宁,韦洪江.α-硫辛酸联合甲钴胺治疗糖尿病周围神经病变的疗效及对氧化应激的影响[J].山东医药,201353(8):13-15.
[5]邹立华,李惠,陈小丹,等.甲钴胺联合α-硫辛酸、血府逐瘀胶囊治疗糖尿病周围神经病变疗效观察[J].中西医结合心脑血管病杂志,2014,12(3):269-270.
[6]HUR J,O'BRIEN P D,NAIR V,et al.Transcriptional networks of murine diabetic peripheral neuropathy and nephropathy common and distinc t gene expression patterns[J]Diabetologia,2016,59(6):1297-1306.
[7]HEWSTON P,DESHPANDE N.Falls and balance impairments in older adults with type 2 diabetes:thinking beyond diabetic peripheral neuropathy[J].Canadian Journal of Diabetes,201640(1):6-9.
[8]吴小芬,罗晓红,徐进,等.木丹颗粒联合甲钴胺及α-硫辛酸治疗糖尿病周围神经病变的疗效观察[J].中华全科医学,2015,13(12):1966-1967.
[9]张永文,韩康生,程燕.糖尿病周围神经病变的中医病因病机及证治[J].吉林中医药,2014,34(6):561-564.
[10]苏玉珂.中医药治疗糖尿病周围神经病变的Meta分析[J]天津中医药,2014,31(6):335-339.
[11]孙朦朦,陈惠,倪青.糖尿病周围神经病变病证结合研究现状及思路探讨[J].长春中医药大学学报,2013,29(2)240-241.
[12]张宏,刘美奇,王旭昀,等.200例糖尿病周围神经病变患者中医证候调查分析[J].长春中医药大学学报,201531(1):99-101.
[13]侯荣.中药穴位敷贴联合中药汤剂治疗糖尿病周围神经病变的临床观察[J].现代中西医结合杂志,2016,25(14)1518-1520.
[14]徐之也.中药汤剂治疗糖尿病周围神经病变临床疗效的Meta分析[D].沈阳:辽宁中医药大学,2013.
[15]吕璐,陆灏.中医内、外治法防治糖尿病周围神经病变研究进展[J].世界临床药物,2017,38(9):593-596.
[16]徐融,杨聘,徐精彩.中医综合疗法治疗糖尿病周围神经病变临床观察[J].中华中医药学刊,2014,32(4):860-862.
[17]袁艺,肖丹,赵波.中医药综合治疗糖尿病周围神经病变临床研究[J].中医学报,2014,29(8):1122-1124.
[18]曹柏龙,苗桂珍,韩文兵,等.火针疗法联合中药改善糖尿病周围神经病变患者临床症状评分疗效观察[J].北京中医药,2014,33(5):380-382.
[19]倪志萍.中药熏洗配合穴位按摩治疗糖尿病周围神经病变疗效观察[J].现代中西医结合杂志,2014,23(34):3797-3799.
[20]白清.黄芪桂枝五物汤对糖尿病周围神经病变的疗效及神经传导速度的影响[J].中成药,2015,37(5):962-964.