基于频数分析和聚类分析的《类证治裁》血证用药规律研究
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摘要
目的:探讨清代医家林珮琴的血证论治规律。方法:收集整理林珮琴《类证治裁》血证部分涉及方药,建立数据库,运用频数分析及聚类分析方法行统计。结果:共纳入方剂152首,中药236味,总用药频次为958次;由频数分析得出林氏治疗血证的高频用药有当归(55),人参(48),天门冬(48),甘草(46),白术(41),熟地黄(38),黄芪(31),茯苓(28),川芎(25),生地黄(24)等;由聚类分析得出血证治疗常用药对8组,角药5组。结论:林氏论治血证,善于运用甘味药;熟谙气血关系,重视升降同调;突出从肾论治的同时,注重诸脏协同配合。
Objective: To explore the law of blood syndrome treatment of LIN Peiqin, a medical doctor in the Qing Dynasty. Methods: Collect and organize blood test part of the prescription of LIN Peiqin's" Leizheng Zhicai" and establish a database, use frequency analysis and cluster analysis method to conduct statistics. RESULTS: A total of 152 prescriptions were obtained, 236 flavors of traditional Chinese medicine, and the frequency of total medication was 958 times. From the frequency analysis, the high-frequency drugs for Lin's treatment of blood syndrome were Danggu(i 55),Renshen(48), Tainmendong(48), Gancao(46), Baizhu(41), Shudihuang(38), Huangqi( 31), Fuling(28),Chuanxiong(25), Shengdihuang(24), 8 herbal pairs and 5 three-drug parings were discovered based on cluster analysis. Conclusions: When treating blood syndromes, Lin prefers to sweet drugs to invigorate spleen, and takes qiblood relations into consideration, laying emphasis on upward and downward movement of Qi distinctively, Lin treats blood syndromes from kidney, attaching importance to coordination of five internal organs.
Objective: To explore the law of blood syndrome treatment of LIN Peiqin, a medical doctor in the Qing Dynasty. Methods: Collect and organize blood test part of the prescription of LIN Peiqin's" Leizheng Zhicai" and establish a database, use frequency analysis and cluster analysis method to conduct statistics. RESULTS: A total of 152 prescriptions were obtained, 236 flavors of traditional Chinese medicine, and the frequency of total medication was 958 times. From the frequency analysis, the high-frequency drugs for Lin's treatment of blood syndrome were Danggu(i 55),Renshen(48), Tainmendong(48), Gancao(46), Baizhu(41), Shudihuang(38), Huangqi( 31), Fuling(28),Chuanxiong(25), Shengdihuang(24), 8 herbal pairs and 5 three-drug parings were discovered based on cluster analysis. Conclusions: When treating blood syndromes, Lin prefers to sweet drugs to invigorate spleen, and takes qiblood relations into consideration, laying emphasis on upward and downward movement of Qi distinctively, Lin treats blood syndromes from kidney, attaching importance to coordination of five internal organs.
引文
[1]方祝元.林珮琴内科学术思想初探[J].江苏中医药,2008,40(1):17-18.
[2]叶瑜,莫志红,莫智旭.历代名医对血证病因病机的研究[J].辽宁中医杂志,2011,38(6):1099-1100.
[3]张佳乐,牛淑平.汪机《石山医案》健脾益气法诊治血证探析[J].甘肃中医药大学学报,2017,34(2):43-45.
[4]朱嗣明.东垣甘温法与治疗血证体会[J].中医药临床杂志,2009,21(3):247-248.
[5]叶冰,吴施国.张琦教授从甘温健脾、升阳举陷论治妇科血证经验撷要[J].四川中医,2009,27(7):14-15.
[6]龙奉玺.喻昌论治血证经验探讨[J].时珍国医国药,2014,25(2):412-413.
[7]吕军.《血证论》平衡观初探[J].南京中医药大学学报,2014,30(1):13-14.
[8]韩家密,黄良文,袁淮涛.治气思想在出血性中风全病程中重要地位探讨[J].中国中医基础医学杂志,2016,22(7):899-900.
[9]刘宇,周雅超,韩雪,等.《血证论》中血上干证学术思想初探[J].中国中医药现代远程教育,2018,16(2):52-55.
[10]徐旻,沈伟.姚乃中运用温肾益精法治疗慢性特发性血小板减少性紫癜经验[J].上海中医药杂志,2017,51(4):6-9.
[11]王珊珊,朱琳,吴其晶.郭立中从温潜论治血证验案3则[J].环球中医药,2016,9(8):989-990.
[12]杨正,孙晓峰,于文明,等.基于数据挖掘的“交通心肾法”用药规律研究[J].中国中医药信息杂志,2016,23(5):40-43.
[13]兰世才,欧阳建军.五行间接补法及其主要体现和名医医案摘录[J].光明中医,2014,29(2):224-225.
[14]车志英,崔丽霞,王国斌.从现代医学角度谈“乙癸同源”的科学性[J].中医研究,2007,20(11):13-14.
[15]甄曙光,欧阳八四,董宏利,等.文本数据挖掘技术在名老中医临床诊疗经验的应用研究[J].中国民族组民间医药,2017,26(22):127-130.
[2]叶瑜,莫志红,莫智旭.历代名医对血证病因病机的研究[J].辽宁中医杂志,2011,38(6):1099-1100.
[3]张佳乐,牛淑平.汪机《石山医案》健脾益气法诊治血证探析[J].甘肃中医药大学学报,2017,34(2):43-45.
[4]朱嗣明.东垣甘温法与治疗血证体会[J].中医药临床杂志,2009,21(3):247-248.
[5]叶冰,吴施国.张琦教授从甘温健脾、升阳举陷论治妇科血证经验撷要[J].四川中医,2009,27(7):14-15.
[6]龙奉玺.喻昌论治血证经验探讨[J].时珍国医国药,2014,25(2):412-413.
[7]吕军.《血证论》平衡观初探[J].南京中医药大学学报,2014,30(1):13-14.
[8]韩家密,黄良文,袁淮涛.治气思想在出血性中风全病程中重要地位探讨[J].中国中医基础医学杂志,2016,22(7):899-900.
[9]刘宇,周雅超,韩雪,等.《血证论》中血上干证学术思想初探[J].中国中医药现代远程教育,2018,16(2):52-55.
[10]徐旻,沈伟.姚乃中运用温肾益精法治疗慢性特发性血小板减少性紫癜经验[J].上海中医药杂志,2017,51(4):6-9.
[11]王珊珊,朱琳,吴其晶.郭立中从温潜论治血证验案3则[J].环球中医药,2016,9(8):989-990.
[12]杨正,孙晓峰,于文明,等.基于数据挖掘的“交通心肾法”用药规律研究[J].中国中医药信息杂志,2016,23(5):40-43.
[13]兰世才,欧阳建军.五行间接补法及其主要体现和名医医案摘录[J].光明中医,2014,29(2):224-225.
[14]车志英,崔丽霞,王国斌.从现代医学角度谈“乙癸同源”的科学性[J].中医研究,2007,20(11):13-14.
[15]甄曙光,欧阳八四,董宏利,等.文本数据挖掘技术在名老中医临床诊疗经验的应用研究[J].中国民族组民间医药,2017,26(22):127-130.