WBC与CRP用于急性期感染小儿肺炎诊断中的价值
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摘要
目的探讨白细胞计数(WBC)与C-反应蛋白(CRP)在急性期感染小儿肺炎中的诊断价值及对病情严重程度的评估作用。方法方便选择该院2017年2月—2018年5月收治的62例确诊为急性期感染小儿肺炎患儿为观察组,其中轻症41例,重症21例,另选62例正常儿童为对照组,所有患儿均进行WBC及CRP检测。结果观察组患儿WBC与CRP水平分别为(18.16±3.07)×10~9/L、(33.06±24.19)g/L,均较对照组(6.21±1.13)×10~9/L、(1.63±1.52)g/L高,差异有统计学意义(t=28.763,10.210,P<0.05);入院第1天观察组轻症患儿的WBC与CRP水平分别为(13.62±4.29)×10~9/L、(21.57±9.86)g/L,较重症患儿(22.54±6.18)×10~9/L、(52.49±24.37)g/L低(t=6.648、7.108,P<0.05),接受治疗后3 d时,轻症患儿WBC与CRP水平分别为(6.74±1.82)×10~9/L、(2.08±2.17)g/L,接近对照组(6.21±1.13)×10~9/L、(1.63±1.52)g/L(t=1.824、1.238,P>0.05),重症患儿(18.16±3.07)×10~9/L、(33.06±24.19)g/L较对照组高(t=26.098、10.294,P<0.05)。结论WBC与CRP在急性期感染小儿肺炎中具有诊断作用,也能判断患儿病情严重程度及疗效,值得临床推广。
Objective To investigate the diagnostic value of white blood cell count(WBC) and C-reactive protein(CRP) in acute infection of children with pneumonia and to evaluate the severity of the disease. Methods 62 children diagnosed with acute infection of children with pneumonia admitted to our hospital from February 2017 to May 2018 were selected as observation groups. Among them, 41 cases were mild and 21 cases were severe.Another 62 normal children were selected as the control group. All patients underwent WBC and CRP tests. Results The WBC and CRP levels in the observation group were(18.16±3.07)×10~9/L and(33.06±24.19) g/L, respectively, compared with the control group(6.21 ±1.13) ×10~9/L,(1.63 ±1.52) g/L was high, the difference was statistically significant(t=28.763,10.210, P<0.05); The WBC and CRP levels in the first-day observation group were(13.62±4.29)×10~9/L,(21.57±9.86) g/L, and those with severe disease(22.54±6.18)×10~9/L,(52.49±24.37)g/L is low(t=6.648,7.108, P<0.05), at 3 days after treatment, the WBC and CRP levels in mild children were(6.74±1.82)×10~9/L,(2.08±2.17) g/L, which was close to the control group(6.21±1.13)×10~9/L,(1.63±1.52)g/L(t=1.824,1.238,P>0.05), Severe children(18.16±3.07)×10~9/L,(33.06±24.19) g/L were higher than the control group(t=26.098,10.294, P<0.05). Conclusion WBC and CRP have a diagnostic role in acute infection of children with pneumonia, and can also judge the severity and efficacy of the disease, which is worthy of clinical promotion.
Objective To investigate the diagnostic value of white blood cell count(WBC) and C-reactive protein(CRP) in acute infection of children with pneumonia and to evaluate the severity of the disease. Methods 62 children diagnosed with acute infection of children with pneumonia admitted to our hospital from February 2017 to May 2018 were selected as observation groups. Among them, 41 cases were mild and 21 cases were severe.Another 62 normal children were selected as the control group. All patients underwent WBC and CRP tests. Results The WBC and CRP levels in the observation group were(18.16±3.07)×10~9/L and(33.06±24.19) g/L, respectively, compared with the control group(6.21 ±1.13) ×10~9/L,(1.63 ±1.52) g/L was high, the difference was statistically significant(t=28.763,10.210, P<0.05); The WBC and CRP levels in the first-day observation group were(13.62±4.29)×10~9/L,(21.57±9.86) g/L, and those with severe disease(22.54±6.18)×10~9/L,(52.49±24.37)g/L is low(t=6.648,7.108, P<0.05), at 3 days after treatment, the WBC and CRP levels in mild children were(6.74±1.82)×10~9/L,(2.08±2.17) g/L, which was close to the control group(6.21±1.13)×10~9/L,(1.63±1.52)g/L(t=1.824,1.238,P>0.05), Severe children(18.16±3.07)×10~9/L,(33.06±24.19) g/L were higher than the control group(t=26.098,10.294, P<0.05). Conclusion WBC and CRP have a diagnostic role in acute infection of children with pneumonia, and can also judge the severity and efficacy of the disease, which is worthy of clinical promotion.
引文
[1]张艺,谢雄.血小板计数对小儿肺炎炎症反应及病情严重程度的评价[J].国际儿科学杂志,2016,43(9):735-737.
[2]葛神永,孙伟.不同病原体感染小儿肺炎降钙素原C-反应蛋白白细胞计数变化情况[J].安徽医学,2017,38(7):904-906.
[3]黄晓妹.降钙素原、C-反应蛋白、白细胞计数在小儿肺炎诊断中的实用价值分析[J].中国实验诊断学,2015,14(1):53-55.
[4]傅雅浓.白细胞计数、C反应蛋白联合呼吸道病原体抗体检测在小儿肺炎的早期诊断价值[J].中国生化药物杂志,2017,28(4):416-418.
[5]张华俐,王超,张蕊,等.发光免疫分析仪联合检测超敏C反应蛋白、降钙素原及免疫功能对小儿肺炎诊断的价值[J].中国医学装备,2016,13(12):109-111,112.
[6]麻小浩,孟清,钟发江,等.超敏C反应蛋白联合血常规用于小儿肺炎支原体感染诊断的临床分析[J].中外医学研究,2013,23(29):48-49.
[7]张林.超敏C反应蛋白及血常规对小儿肺炎支原体感染的临床诊断价值分析[J].临床和实验医学杂志,014,32(10):840-842.
[8]王凤娇,田海容,陈天昱,等.血清CRP、WBC及P CT检测在小儿肺炎诊断中的临床应用[J].齐齐哈尔医学院学报,2016,37(24):3015-3016.
[9]孙种梅.降钙素原、超敏C反应蛋白水平与白细胞计数联合检测对小儿肺炎的临床诊断价值[J].世界临床医学,2017,11(13):226.
[10]马立.全血C-反应蛋白与白细胞计数联合检测在小儿肺炎中的应用分析[J].当代医学,2017,23(10):132-134.
[11]申宛冬.小儿肺炎诊断中降钙素原、C-反应蛋白、白细胞计数的临床价值分析[J].深圳中西医结合杂志,2017,27(7):28-29.
[12]王灵芝.急性期感染小儿肺炎患儿C-反应蛋白、白细胞及Ig水平的变化及临床治疗效果[J].中国妇幼保健,2016,31(8):1648-1650.
[2]葛神永,孙伟.不同病原体感染小儿肺炎降钙素原C-反应蛋白白细胞计数变化情况[J].安徽医学,2017,38(7):904-906.
[3]黄晓妹.降钙素原、C-反应蛋白、白细胞计数在小儿肺炎诊断中的实用价值分析[J].中国实验诊断学,2015,14(1):53-55.
[4]傅雅浓.白细胞计数、C反应蛋白联合呼吸道病原体抗体检测在小儿肺炎的早期诊断价值[J].中国生化药物杂志,2017,28(4):416-418.
[5]张华俐,王超,张蕊,等.发光免疫分析仪联合检测超敏C反应蛋白、降钙素原及免疫功能对小儿肺炎诊断的价值[J].中国医学装备,2016,13(12):109-111,112.
[6]麻小浩,孟清,钟发江,等.超敏C反应蛋白联合血常规用于小儿肺炎支原体感染诊断的临床分析[J].中外医学研究,2013,23(29):48-49.
[7]张林.超敏C反应蛋白及血常规对小儿肺炎支原体感染的临床诊断价值分析[J].临床和实验医学杂志,014,32(10):840-842.
[8]王凤娇,田海容,陈天昱,等.血清CRP、WBC及P CT检测在小儿肺炎诊断中的临床应用[J].齐齐哈尔医学院学报,2016,37(24):3015-3016.
[9]孙种梅.降钙素原、超敏C反应蛋白水平与白细胞计数联合检测对小儿肺炎的临床诊断价值[J].世界临床医学,2017,11(13):226.
[10]马立.全血C-反应蛋白与白细胞计数联合检测在小儿肺炎中的应用分析[J].当代医学,2017,23(10):132-134.
[11]申宛冬.小儿肺炎诊断中降钙素原、C-反应蛋白、白细胞计数的临床价值分析[J].深圳中西医结合杂志,2017,27(7):28-29.
[12]王灵芝.急性期感染小儿肺炎患儿C-反应蛋白、白细胞及Ig水平的变化及临床治疗效果[J].中国妇幼保健,2016,31(8):1648-1650.