阿奇霉素与头孢菌素治疗支气管哮喘疗效观察
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摘要
目的观察分析阿奇霉素与头孢菌素联合多索茶碱,并吸入布地奈德对治疗支气管哮喘的安全性和疗效。方法随机抽取本院78例轻中度支气管哮喘患者,分为对照组和治疗组,每组患者均为39例。对照组采用头孢菌素联合多索茶碱静脉点滴,吸入布地奈德治疗;治疗组采用阿奇霉素联合多索茶碱静脉点滴,吸入布地奈德治疗。观察两组疗效。结果治疗5日后,对照组患者8例痊愈,15例有效,16例无效,一秒用力呼气容积(FEV1)的增加均小于16%;治疗组患者34例症状及体征明显好转或消失,肺活量、用力肺活量(FVC)、FEV1和呼气峰值流速(PEFR)显著增加(P<0.05), 5例无效;对照组明显差于治疗组,两组相比,P<0.05,有显著统计学差异。结论阿奇霉素治疗支气管哮喘疗效明显好于头孢菌素。
Objective To observe the analysis of the safety and efficacy of azithromycin and cephalosporin combined with doxofylline and inhaled budesonide for the treatment of asthma. Methods A total of 78 patients with mild to moderate asthma were randomly divided into the control group and the treatment group, with 39 patients in each group. The control group was treated with cephalosporin combined with doxofylline intravenously and inhaled budesonide. The treatment group was treated with azithromycin combined with doxofylline intravenously and inhaled budesonide. The efficacy of the two groups was observed. Results After 5 days of treatment, 8 patients in the control group recovered, 15 effective, 16 were ineffective, and the increase in FEV1 was less than 16%,the symptoms and signs of the 34 patients in the treatment group were significantly improved or disappeared, and the vital capacity,FVC, FEV1 and PEFR were significant increased(P<0.05), 5 cases were ineffective; the control group was significantly worse than the treatment group, P<0.05, compared with the two groups, there was a significant statistical difference. Conclusion Azithromycin is more effective than cephalosporin in the treatment of bronchial asthma.
Objective To observe the analysis of the safety and efficacy of azithromycin and cephalosporin combined with doxofylline and inhaled budesonide for the treatment of asthma. Methods A total of 78 patients with mild to moderate asthma were randomly divided into the control group and the treatment group, with 39 patients in each group. The control group was treated with cephalosporin combined with doxofylline intravenously and inhaled budesonide. The treatment group was treated with azithromycin combined with doxofylline intravenously and inhaled budesonide. The efficacy of the two groups was observed. Results After 5 days of treatment, 8 patients in the control group recovered, 15 effective, 16 were ineffective, and the increase in FEV1 was less than 16%,the symptoms and signs of the 34 patients in the treatment group were significantly improved or disappeared, and the vital capacity,FVC, FEV1 and PEFR were significant increased(P<0.05), 5 cases were ineffective; the control group was significantly worse than the treatment group, P<0.05, compared with the two groups, there was a significant statistical difference. Conclusion Azithromycin is more effective than cephalosporin in the treatment of bronchial asthma.
引文
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[7]潘存勇,张保栋.止哮方联合西药治疗支气管哮喘疗效观察[J].中国继续医学教育,2017(05):184-186.
[8]谢东.中西医药结合治疗支气管哮喘疗效观察[J].四川中医,2014(10):86-88.
[2]孙金霞,崔玉宝.哮喘的遗传学研究进展[J].医学综述,2014,20(1):3-7.
[3]朱朝霞.阿奇霉素治疗支气管哮喘80例[J].中国药业,2012,21(9):56-56.
[4]李丽娟.阿奇霉素与头孢菌素治疗支气管哮喘疗效观察[J].世界最新医学信息文摘,2016,16(91):104.
[5]高杰.阿奇霉素治疗小儿支气管哮喘的疗效观察[J].中国医药指南,2013(13):543-544.
[6]罗刚.阿奇霉素联合头孢类抗生素治疗小儿支原体肺炎的临床效果分析[J].世界最新医学信息文摘,2018,18(63):112-112.
[7]潘存勇,张保栋.止哮方联合西药治疗支气管哮喘疗效观察[J].中国继续医学教育,2017(05):184-186.
[8]谢东.中西医药结合治疗支气管哮喘疗效观察[J].四川中医,2014(10):86-88.