超高效液相色谱法在中药分析领域中的应用现状及展望
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摘要
中药具有化学成分复杂、性质差异大、分离困难等特点,药学工作者尝试运用各种分析方法来解析中药中的成分。随着液相色谱技术的发展,在中药分析领域的应用逐渐增多,也进一步促进了中药的深入研究。对超高效液相色谱的发展历程进行了梳理,并总结了其在中药分析领域中的应用现状,展望了超高效液相色谱未来的发展方向,为促进超高效液相色谱法在中药分析领域中更合理、更广泛的普及应用提供参考。
Chinese materia medica(CMM) have many unique characteristics, such as complex chemical compositions, large differences in properties, and difficulty in separation. Pharmacists try to use various analytical methods to analyze the chemical compositions in CMM. With the development of liquid chromatography technology, the ultra-high performance liquid chromatography(UPLC) has been applied in the analysis field of CMM, and further promoted the in-depth study of CMM. This paper summarizes the development history of HPLC and UPLC, describes its current application in the analysis field of CMM, and provides an outlook of the future development of UPLC. The purpose of this paper is to promote the more reasonable and wider application of UPLC in the field of CMM analysis.
Chinese materia medica(CMM) have many unique characteristics, such as complex chemical compositions, large differences in properties, and difficulty in separation. Pharmacists try to use various analytical methods to analyze the chemical compositions in CMM. With the development of liquid chromatography technology, the ultra-high performance liquid chromatography(UPLC) has been applied in the analysis field of CMM, and further promoted the in-depth study of CMM. This paper summarizes the development history of HPLC and UPLC, describes its current application in the analysis field of CMM, and provides an outlook of the future development of UPLC. The purpose of this paper is to promote the more reasonable and wider application of UPLC in the field of CMM analysis.
引文
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[24]李莉,叶晓川,宋小英,等.UPLC-DAD-ELSD切换波长法同时测定复方酸枣仁颗粒中8种成分的含量[J].药物分析杂志,2016,36(10):1722-1728.
[25]孙冬梅,林晓燕,刘梦云,等.复方芪麻胶囊UPLC指纹图谱建立和同时测定8种成分研究[J].中草药,2016,47(23):4186-4191.
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