Self-reported participation restrictions in normal hearing individuals in thyroid ontogeny: Evidence of subclinical changes
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摘要
Purpose: To verify evidence of subclinical alterations through self-reported participation restrictions in normal hearing individuals and congenital hypothyroidism patients.Methods: An analytical, quantitative, cross-sectional exploratory study with a 1:1 ratio, consisting of a convenience sample of 86 normal hearing individuals with(n = 42) and without(n = 44) congenital hypothyroidism diagnosis. All participants underwent tonal and speech audiometry, immitance and distortion product otoacoustic emissions. The researchers excluded people with hearing loss, genetic syndromes and metabolic diseases. The instrument used for evaluate of self-reported participation restrictions was the HHIE-adapted questionnaire, composed of 25 questions, 12 of which were social domain and 13 emotional domain. Student's ttest and chi-square test were used for statistical analysis at a significance level of 5%.Results: There was a significant(p < 0.001) self-reported participation restrictions in CH(61.9%), with a greater relevance for the social domain(p = 0.002). There was a greater frequency of mild/moderate(40.5%)and higher prevalence of association with clinical factors and adherence to treatment.Conclusion: The findings indicate that self-reported participation restrictions in normal hearing individuals with congenital hypothyroidism was more significant than in the non-exposed group, suggesting evidence of subclinical auditory abnormalities in this population.
Purpose: To verify evidence of subclinical alterations through self-reported participation restrictions in normal hearing individuals and congenital hypothyroidism patients.Methods: An analytical, quantitative, cross-sectional exploratory study with a 1:1 ratio, consisting of a convenience sample of 86 normal hearing individuals with(n = 42) and without(n = 44) congenital hypothyroidism diagnosis. All participants underwent tonal and speech audiometry, immitance and distortion product otoacoustic emissions. The researchers excluded people with hearing loss, genetic syndromes and metabolic diseases. The instrument used for evaluate of self-reported participation restrictions was the HHIE-adapted questionnaire, composed of 25 questions, 12 of which were social domain and 13 emotional domain. Student's ttest and chi-square test were used for statistical analysis at a significance level of 5%.Results: There was a significant(p < 0.001) self-reported participation restrictions in CH(61.9%), with a greater relevance for the social domain(p = 0.002). There was a greater frequency of mild/moderate(40.5%)and higher prevalence of association with clinical factors and adherence to treatment.Conclusion: The findings indicate that self-reported participation restrictions in normal hearing individuals with congenital hypothyroidism was more significant than in the non-exposed group, suggesting evidence of subclinical auditory abnormalities in this population.
Purpose: To verify evidence of subclinical alterations through self-reported participation restrictions in normal hearing individuals and congenital hypothyroidism patients.Methods: An analytical, quantitative, cross-sectional exploratory study with a 1:1 ratio, consisting of a convenience sample of 86 normal hearing individuals with(n = 42) and without(n = 44) congenital hypothyroidism diagnosis. All participants underwent tonal and speech audiometry, immitance and distortion product otoacoustic emissions. The researchers excluded people with hearing loss, genetic syndromes and metabolic diseases. The instrument used for evaluate of self-reported participation restrictions was the HHIE-adapted questionnaire, composed of 25 questions, 12 of which were social domain and 13 emotional domain. Student's ttest and chi-square test were used for statistical analysis at a significance level of 5%.Results: There was a significant(p < 0.001) self-reported participation restrictions in CH(61.9%), with a greater relevance for the social domain(p = 0.002). There was a greater frequency of mild/moderate(40.5%)and higher prevalence of association with clinical factors and adherence to treatment.Conclusion: The findings indicate that self-reported participation restrictions in normal hearing individuals with congenital hypothyroidism was more significant than in the non-exposed group, suggesting evidence of subclinical auditory abnormalities in this population.
引文
Aiello,C.P.,Lima II,,Ferrari,D.V.,Ferrari,D.V.,2011.Validity and reliability of the hearing handicap inventory for Adults.Braz.J.Otorhinolaryngol.77(4),432-438.
Andrade,C.L.,Machado,G.C.,Fernandes,L.C.,Braga,H.,Boa-Sorte,N.,Ramos,H.E.,et al.,2017.Prevalência de sintomas otoneurológicos em indivíduos com hipotireoidismo congênito:estudo piloto.Cad saúde colet 25(2),144-151.
Andrade,C.L.O.,Lemos,A.C.,Machado,G.C.,Fernandes,L.C.,Silva,L.L.,Oliveira,H.B.,et al.,2018.Congenital hypothyroidism as a risk factor for central hearing process disorders.Rev paul pediatr[Internet].[cited 2018 Sep 08].Available from.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822018005010102&lng=en(in press),Epub Aug 30,2018.
Baruzzi,M.B.,Borges,A.C.L.C.,Ribeiro,M.I.,Nasri,F.,2009.Self-perceived hearing handicap and hearing sensitivity in nursing home elderlies.Einstein 7(2),176-181.
Bellman,S.C.,Davies,A.,Fuggle,P.W.,Grant,D.B.,Smith,I.,1996.Mild impairment of neuro-otological function in early treated congenital hypothyroidism.Arch.Dis.Child.74(3),215-218.
Bernabei,V.,Morini,V.,Moretti,F.,Marchiori,A.,Ferrari,B.,Dalmonte,E.,et al.,2011.Vision and hearing impairments are associated with depressive-anxiety.Aging Ment.Health 15(4),467-474.
Brazil,2012.Protocolo de tratamento e acompanhamento clínico de crian?as com hipotireoidismo congênito do Programa de Triagem Neonatal de Minas Gerais/coordenado por Ant?nio Josédas Chagas,et al.NUPAD,Belo Horizonte,pp.38.
Brenta,G.,Vaisman,M.,Sgarbi,J.A.,Bergoglio,L.M.,Andrada,N C de,Bravo,P.P.,et al.,2013.Diretrizes clínicas práticas para o manejo do hipotiroidismo.Arq.Bras.Endocrinol.Metabol.57(4),265-291.
Brucker-Davis,F.,Skarulis,M.C.,Pikus,A.,Ishizawar,D.,Mastroianni,M.A.,Koby,M.,et al.,1996.Prevalence and mechanisms of hearing loss in.patients with resistance to thyroid hormone.J.Clin.Endocrinol.Metab.81(8),2768-2772.
Canlon,B.,Theorell,T.,Hasson,D.,2013.Associations between stress and hearing problems in humans.Hear.Res.295,9-15.
Carvalho,R.M.,Iório,M.C.M.,2007.Eficácia da aplica??o do questionário de handicap em idosos deficientes auditivos.Distúrb comum.19(2),163-172.
Fernandes,L.C.,Andrade,C.L.,Fernando,L.F.A.,Cruz,M.L.,Araújo,M.C.,Casais-e-Silva,L.,et al.,2014.Associations between hearing handicap,metabolic control and other otoneurological disturbances in individuals with type 1 diabetes mellitus.Int.J.Diabetes Dev.Ctries.35(3),171-176.
Fire,K.M.,Lesner,S.A.,Newman,C.,1991.Hearing handicap as a function of central auditory abilities in the elderly.Am.J.Otol.12(2),105-108.
Gej?o,M.G.,Ferreira,A.T.,Silva,G.K.,Anastácio-Pessan,F.L.,Lam?nica,D.A.C.,2009.Communicative and psycholinguistic abilities in children with phenylketonuria and congenital hypothyroidism.J.Appl.Oral Sci.17,69-75.
Hallberg,L.R.,Hallberg,U.,Kramer,S.E.,2008.Self-reported hearing difficulties,communication strategies and psychological general well-being(quality of life)in patients with acquired hearing impairment.Disabil.Rehabil.30(3),203-212.
Hashemipour,M.,Hovsepian,S.,Hashemi,M.,Amini,M.,Kelishadi,R.,Sadeghi,S.,2012.Hearing impairment in congenitally hypothyroid patients.Iran.J.Pediatr.22(1),92-96.
Helvik,A.S.,Jacobsen,G.,Hallberg,L.R.,2006.Psychological well-being of adults with acquired hearing impairment.Disabil.Rehabil.28(9),535-545.
Lichtenberger-Geslin,L.,Dos Santos,S.,Hassani,Y.,Ecosse,E.,Van Den Abbeele,T.,Léger,J.,2013.Factors associated with hearing impairment in.patients with congenital hypothyroidism treated since the neonatal period:a national population.based study.J.Clin.Endocrinol.Metab.98(9),3644-3652.
Lloyd,L.L.,Kaplan,H.,1978.Audiometric Interpretation:a Manual of Basic Audiometry.University Park Press,Baltimore,pp.15-17.
Marti,S.,Alvarez,M.,Simoneau-Roy,J.,Leroux,S.,Van Vliet,G.,Robaey,P.,2006.Effects of early high-dose levothyroxine treatment on auditory brain event-related potentials at school entry in children with congenital hypothyroidism.Horm.Res.66(5),240-248.
Menegotto,I.H.,Soldera,C.L.C.,Anderle,P.,Anhaia,T.C.,2011.Correla??o entre perdaauditiva e resultados dos questionários hearing handicap inventory for the adults:screening version HHIA-S e hearing handicap inventory for the elderly-screening version-HHIE-S.Arq.Int.Otorrinolaringol.15(3),319-326.
Pajor,A.,Ormezowska,E.,Jozefowicz-Korczynska,M.,2013.The impact of co-morbid factors on the psychological outcome of tinnitus patients.Eur.Arch.Oto-RhinoLaryngol.270(3),881-888.
Psaltakos,V.,Balatsouras,D.G.,Sengas,I.,Ferekidis,E.,Riga,M.,Korres,S.G.,2013.Cochlear dysfunction in patients with acute hypothyroidism.Eur.Arch.Oto-RhinoLaryngol.270(11),2839-2848.
Rocco,B.,Tommaso,A.,Mariaausilia,C.,Mariella,V.,Fortunato,L.,Filippo De,L.,et al.,2015.Even in the era of congenital hypothyroidism screening mild and subclinical sensorineural hearing loss remains a relatively common complication of severe congenital hypothyroidism.Hear.Res.327,43.
Rosalino,C.V.,Rozenfeld,S.,2005.Triagem auditiva em idosos:compara??o entre autorelato e audiometria.Rev.Bras.Otorrinolaringol.71(2),193-200.
Rovet,J.,Walker,W.,Bliss,B.,Buchanan,L.,Ehrlich,R.,1996.Long-term sequelae of hearing impairment in congenital hypothyroidism.J.Pediatr.128(6),776-783.
Silman,S.,Silverman,C.A.,1997.Basic audiologic testing.In:Silman,S.,Silverman,C.A.(Eds.),Auditory Diagnosis:Principles and Applications.Singular Publishing Group,San Diego,pp.44-52.
Sininger,Y.S.,Abdala,C.,Cone-Wesson,B.,1997.Auditory threshold sensitivity of the human neonate as measured by the auditory brainstem response.Hear.Res.104(1-2),27-38.
Sohmer,H.,Freeman,S.,1996.The importance of thyroid hormone for auditory development in the fetus and neonate.Audiol.Neurotol.1(3),137-147.
Weinstein,B.E.,1999.Presbiacusia.In:Katz,J.(Ed.),Tratado de audiologia clínica.Manole,S?o Paulo,pp.562-577.
Weinstein,B.E.,Spitzer,J.B.,Ventry,I.M.,1986.Test-retest reliability of the hearing handicap inventory for the elderly.Ear Hear.7(5),295-299.
Wieselberg,M.B.,Sousa,M.C.F.,2013.Aconselhamento na reabilita??o audiológica.In:Filho,OLE,org.Novo tratado de fonoaudiologia.Manole,Barueri,pp.737-756.
Andrade,C.L.,Machado,G.C.,Fernandes,L.C.,Braga,H.,Boa-Sorte,N.,Ramos,H.E.,et al.,2017.Prevalência de sintomas otoneurológicos em indivíduos com hipotireoidismo congênito:estudo piloto.Cad saúde colet 25(2),144-151.
Andrade,C.L.O.,Lemos,A.C.,Machado,G.C.,Fernandes,L.C.,Silva,L.L.,Oliveira,H.B.,et al.,2018.Congenital hypothyroidism as a risk factor for central hearing process disorders.Rev paul pediatr[Internet].[cited 2018 Sep 08].Available from.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-05822018005010102&lng=en(in press),Epub Aug 30,2018.
Baruzzi,M.B.,Borges,A.C.L.C.,Ribeiro,M.I.,Nasri,F.,2009.Self-perceived hearing handicap and hearing sensitivity in nursing home elderlies.Einstein 7(2),176-181.
Bellman,S.C.,Davies,A.,Fuggle,P.W.,Grant,D.B.,Smith,I.,1996.Mild impairment of neuro-otological function in early treated congenital hypothyroidism.Arch.Dis.Child.74(3),215-218.
Bernabei,V.,Morini,V.,Moretti,F.,Marchiori,A.,Ferrari,B.,Dalmonte,E.,et al.,2011.Vision and hearing impairments are associated with depressive-anxiety.Aging Ment.Health 15(4),467-474.
Brazil,2012.Protocolo de tratamento e acompanhamento clínico de crian?as com hipotireoidismo congênito do Programa de Triagem Neonatal de Minas Gerais/coordenado por Ant?nio Josédas Chagas,et al.NUPAD,Belo Horizonte,pp.38.
Brenta,G.,Vaisman,M.,Sgarbi,J.A.,Bergoglio,L.M.,Andrada,N C de,Bravo,P.P.,et al.,2013.Diretrizes clínicas práticas para o manejo do hipotiroidismo.Arq.Bras.Endocrinol.Metabol.57(4),265-291.
Brucker-Davis,F.,Skarulis,M.C.,Pikus,A.,Ishizawar,D.,Mastroianni,M.A.,Koby,M.,et al.,1996.Prevalence and mechanisms of hearing loss in.patients with resistance to thyroid hormone.J.Clin.Endocrinol.Metab.81(8),2768-2772.
Canlon,B.,Theorell,T.,Hasson,D.,2013.Associations between stress and hearing problems in humans.Hear.Res.295,9-15.
Carvalho,R.M.,Iório,M.C.M.,2007.Eficácia da aplica??o do questionário de handicap em idosos deficientes auditivos.Distúrb comum.19(2),163-172.
Fernandes,L.C.,Andrade,C.L.,Fernando,L.F.A.,Cruz,M.L.,Araújo,M.C.,Casais-e-Silva,L.,et al.,2014.Associations between hearing handicap,metabolic control and other otoneurological disturbances in individuals with type 1 diabetes mellitus.Int.J.Diabetes Dev.Ctries.35(3),171-176.
Fire,K.M.,Lesner,S.A.,Newman,C.,1991.Hearing handicap as a function of central auditory abilities in the elderly.Am.J.Otol.12(2),105-108.
Gej?o,M.G.,Ferreira,A.T.,Silva,G.K.,Anastácio-Pessan,F.L.,Lam?nica,D.A.C.,2009.Communicative and psycholinguistic abilities in children with phenylketonuria and congenital hypothyroidism.J.Appl.Oral Sci.17,69-75.
Hallberg,L.R.,Hallberg,U.,Kramer,S.E.,2008.Self-reported hearing difficulties,communication strategies and psychological general well-being(quality of life)in patients with acquired hearing impairment.Disabil.Rehabil.30(3),203-212.
Hashemipour,M.,Hovsepian,S.,Hashemi,M.,Amini,M.,Kelishadi,R.,Sadeghi,S.,2012.Hearing impairment in congenitally hypothyroid patients.Iran.J.Pediatr.22(1),92-96.
Helvik,A.S.,Jacobsen,G.,Hallberg,L.R.,2006.Psychological well-being of adults with acquired hearing impairment.Disabil.Rehabil.28(9),535-545.
Lichtenberger-Geslin,L.,Dos Santos,S.,Hassani,Y.,Ecosse,E.,Van Den Abbeele,T.,Léger,J.,2013.Factors associated with hearing impairment in.patients with congenital hypothyroidism treated since the neonatal period:a national population.based study.J.Clin.Endocrinol.Metab.98(9),3644-3652.
Lloyd,L.L.,Kaplan,H.,1978.Audiometric Interpretation:a Manual of Basic Audiometry.University Park Press,Baltimore,pp.15-17.
Marti,S.,Alvarez,M.,Simoneau-Roy,J.,Leroux,S.,Van Vliet,G.,Robaey,P.,2006.Effects of early high-dose levothyroxine treatment on auditory brain event-related potentials at school entry in children with congenital hypothyroidism.Horm.Res.66(5),240-248.
Menegotto,I.H.,Soldera,C.L.C.,Anderle,P.,Anhaia,T.C.,2011.Correla??o entre perdaauditiva e resultados dos questionários hearing handicap inventory for the adults:screening version HHIA-S e hearing handicap inventory for the elderly-screening version-HHIE-S.Arq.Int.Otorrinolaringol.15(3),319-326.
Pajor,A.,Ormezowska,E.,Jozefowicz-Korczynska,M.,2013.The impact of co-morbid factors on the psychological outcome of tinnitus patients.Eur.Arch.Oto-RhinoLaryngol.270(3),881-888.
Psaltakos,V.,Balatsouras,D.G.,Sengas,I.,Ferekidis,E.,Riga,M.,Korres,S.G.,2013.Cochlear dysfunction in patients with acute hypothyroidism.Eur.Arch.Oto-RhinoLaryngol.270(11),2839-2848.
Rocco,B.,Tommaso,A.,Mariaausilia,C.,Mariella,V.,Fortunato,L.,Filippo De,L.,et al.,2015.Even in the era of congenital hypothyroidism screening mild and subclinical sensorineural hearing loss remains a relatively common complication of severe congenital hypothyroidism.Hear.Res.327,43.
Rosalino,C.V.,Rozenfeld,S.,2005.Triagem auditiva em idosos:compara??o entre autorelato e audiometria.Rev.Bras.Otorrinolaringol.71(2),193-200.
Rovet,J.,Walker,W.,Bliss,B.,Buchanan,L.,Ehrlich,R.,1996.Long-term sequelae of hearing impairment in congenital hypothyroidism.J.Pediatr.128(6),776-783.
Silman,S.,Silverman,C.A.,1997.Basic audiologic testing.In:Silman,S.,Silverman,C.A.(Eds.),Auditory Diagnosis:Principles and Applications.Singular Publishing Group,San Diego,pp.44-52.
Sininger,Y.S.,Abdala,C.,Cone-Wesson,B.,1997.Auditory threshold sensitivity of the human neonate as measured by the auditory brainstem response.Hear.Res.104(1-2),27-38.
Sohmer,H.,Freeman,S.,1996.The importance of thyroid hormone for auditory development in the fetus and neonate.Audiol.Neurotol.1(3),137-147.
Weinstein,B.E.,1999.Presbiacusia.In:Katz,J.(Ed.),Tratado de audiologia clínica.Manole,S?o Paulo,pp.562-577.
Weinstein,B.E.,Spitzer,J.B.,Ventry,I.M.,1986.Test-retest reliability of the hearing handicap inventory for the elderly.Ear Hear.7(5),295-299.
Wieselberg,M.B.,Sousa,M.C.F.,2013.Aconselhamento na reabilita??o audiológica.In:Filho,OLE,org.Novo tratado de fonoaudiologia.Manole,Barueri,pp.737-756.