摘要
目的了解企业低浓度苯系物暴露作业对工人血常规指标的影响。方法选择南昌市某印钞企业胶印车间、凹印车间和印码车间的265名低浓度苯系物作业工人作为暴露组,选择同一地区某手机零件生产企业175名噪声作业工人作为对照组,对2组人群进行一般情况调查和血常规检测,同时将暴露组按工龄长短进行分组比较,并对暴露组中均参加了2012年和2017年职业健康检查的136名工人的血常规指标进行比较。结果车间空气各监测点苯系物浓度均低于国家职业接触限值。暴露组与对照组相比,除血小板计数暴露组低于对照组外,其余血常规指标白细胞计数、红细胞计数、血红蛋白差异均无统计学意义(均P>0.05)。将暴露组按照工龄长短分为1~5年(89人),6~10年(77人),11~15年(19人),16~20年(16人),>20年(64人)共5组,各组血常规指标差异均无统计学意义(均P>0.05)。将2012年与2017年的血常规指标对比分析,各项指标差异均无统计学意义(均P>0.05)。结论未发现企业低浓度苯系物暴露可引起工人血常规指标的明显改变。
[ Objective ] To understand the influence of low concentration benzene series exposure on workers' blood routine indexes.[Methods] A total of 265 workers exposed to low concentration benzene series in the offset workshop, intaglio shop and printing shop of a printing banknote enterprise in Nanchang City were selected as exposure group, and 175 noise-exposed workers of a mobile phone part production enterprise in the same area were selected as the control group. The general situation investigation and blood routine test were carried out in the two groups. Meanwhile, the exposure group was grouped according to the length of service, and the blood routine indexes of 136 workers who participated in the occupational health examination in2012 and 2017 were compared.[Results] The concentration of benzene series in each monitoring point of the workshop was lower than the national occupational exposure limit. The platelet count in the exposure group was lower than that in the control group,while the differences in the rest blood routine indexes, including white blood count, red blood cell count and hemoglobin, were not statistically significant between the exposure group and the control group(all P>0.05). The workers in the exposure group were divided into five groups according to the length of service, including 1-5 years group(89 workers), 6-10 years group(77 workers),11-15 years group(19 workers), 16-20 years group(16 workers), and >20 years group(64 workers), and there were no statistically significant differences in blood routine indexes among five groups(all P>0.05). There were no statistically significant differences in blood routine indexes among results in 2012 and 2017(all P>0.05). [Conclusion ] There is no evidence that exposure to low concentration benzene series could cause significant changes in blood routine indexes of workers.
引文
[1]中华人民共和国卫生部政策法规司.工作场所空气中有害物质监测的采样规范:GBZ 159-2004[S].北京:人民卫生出版社,2006:1-9.
[2]中华人民共和国卫生部政策法规司.工作场所空气有毒物质测定芳香烃类化合物:GBZ/T 160.42-2007[S].北京:人民卫生出版社,2008:1-10.
[3]中华人民共和国卫生部政策法规司.工作场所有害因素职业接触限值第1部分:化学有害因素:GBZ 2.1-2007[S].北京:人民卫生出版社,2008:2-6.
[4]何凤生.中华职业医学[M].北京:人民卫生出版社.1999:471.
[5]袁建辉,杨建平,朱志良,等.2006—2011年深圳市宝安区企业使用苯系物调查[J].职业与健康,2012,28(24):3059-3064.
[6]查建溪,林惠芳,张巧红,等.低浓度苯系物对作业工人的健康影响[J].职业与健康,2010,26(16):1828-1829.
[7]李敏.低浓度混苯暴露对作业工人外周血象影响的调查[J].公共卫生与预防医学,2013,24(3):92-93.
[8]苏冬梅,陈新,王丹蕾,等.郑州市某汽车制造企业低浓度苯作业对男性工人血常规的影响[J].职业与健康,2016,32(12):1617-1619.
[9]王胜利,刘仁平,茅辉军,等.某工业园区接触工业用混苯工人健康状况及接触水平[J].中华劳动卫生职业病杂志,2013,31(11):846-847.
[10]王秋艳,周久利,齐秀芳,等.苯作业人员血样放置时间对血常规检测结果的影响[J].河北医药,2012,34(2):282.
[11]马茜,董水清.某电器公司长期接触低浓度苯、甲苯和二甲苯对作业人员健康的影响[J].职业与健康,2013,29(22):2969-2971.
[12]陈利杰.长期低浓度混苯暴露对制漆作业工人健康的影响[J].河南医学研究,2017,26(12):2165-2166.
[13]张静,吕建萍,张晨,等.低浓度苯作业工人健康状况及影响因素分析[J].中国公共卫生,2012,28(8):1020-1022.
[14]王芳,师伟,魏云芳,等.低浓度苯对作业工人血液系统的影响[J].中国工业医学杂志,2014,27(3):202-204.
[15]黄丽静.低浓度苯接触对作业工人血常规水平的影响分析[J].当代医学,2015,21(22):159-160.
[16]苏广校,林道建.低浓度职业性苯接触对男工血液系统的影响[J].职业卫生与应急救援,2016,34(5):386-387.
[17]任春霞,田建功,海铭真,等.某企业苯作业人员血常规结果分析[J].职业卫生与应急救援,2017,35(2):126-127.