早期先兆流产合并绒毛膜下血肿的影响因素及中医证型分布规律
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摘要
目的探讨早期先兆流产合并绒毛膜下血肿的影响因素,及中医证型在早期先兆流产合并绒毛膜下血肿患者不同孕周的分布规律。方法选取2017年3月～2018年3月期间江西省妇幼保健院确诊的100例早期先兆流产合并绒毛膜下血肿并住院治疗的患者为研究组,另选择100例本院待产人群中孕早期无先兆流产症状者为对照组。比较两组不良生活习惯(包括接触化学污染物、严重负面情绪、服用激素药物)、流产次数及早期先兆流产合并绒毛膜下血肿的中医证型分布规律(包括血瘀阻滞证、湿热内蕴证、阴虚血热证、血热证、气血虚弱证、肾气亏虚证)。结果研究组不良生活习惯明显高于对照组(P<0.05);研究组流产次数与对照组比较有明显差异(P<0.05);早期先兆流产合并绒毛膜下血肿患者不同孕周的中医证型分布规律差异有统计学意义(P<0.05)。结论患者的不良生活习惯和流产次数是早期先兆流产合并绒毛膜下血肿的主要影响因素;孕妇的孕周和早期先兆流产合并绒毛膜下血肿的中医证型分布有密切关系,且肾气亏虚证是早期先兆流产合并绒毛膜下血肿中医证型的主要证型。
Objective To investigate the influencing factors of early threatened abortion complicated with subchorionic hematoma, and the distribution principle of TCM syndromes in the patients with early threatened abortion complicated with subchorionic hematoma in different gestational weeks. Methods A total of 100 patients with early threatened abortion complicated with subchorionic hematoma diagnosed and hospitalized in Jiangxi Women and Children's Hospital from March 2017 to March 2018 were selected as the study group. Another 100 pregnancy women in their early trimester without symptoms of early threatened abortion in our hospital were selected as the control group. The negative life habits(including exposure to chemical pollutants, severe negative emotions,taking hormonal drugs), the number of abortions and the distribution principle of TCM syndromes in early threatened abortion complicated with subchorionic hematoma(including blood stasis syndrome, dampness and heat syndrome, yin deficiency and blood heat syndrome,blood heat syndrome, qi and blood deficiency syndrome,kidney qi deficiency syndrome) were compared between the two groups. Results The negative life habits in the study group were significantly more than those in the control group(P<0.05); the number of abortions in the study group was significantly different from that in the control group( P<0.05);there was statistically significant differences in the distribution principle of TCM syndromes in the patients with early threatened abortion complicated with subchorionic hematoma in different gestational weeks(P<0.05). Conclusion The negative life habits and frequency of abortion are the main influencing factors for early threatened abortion complicated with subchorionic hematoma; there is a close relationship between the gestational weeks of pregnant women and the distribution of TCM syndromes in early threatened abortion complicated with subchorionic hematoma. The kidney qi deficiency syndrome is the main syndrome type of early threatened abortion complicated with subchorionic hematoma.
Objective To investigate the influencing factors of early threatened abortion complicated with subchorionic hematoma, and the distribution principle of TCM syndromes in the patients with early threatened abortion complicated with subchorionic hematoma in different gestational weeks. Methods A total of 100 patients with early threatened abortion complicated with subchorionic hematoma diagnosed and hospitalized in Jiangxi Women and Children's Hospital from March 2017 to March 2018 were selected as the study group. Another 100 pregnancy women in their early trimester without symptoms of early threatened abortion in our hospital were selected as the control group. The negative life habits(including exposure to chemical pollutants, severe negative emotions,taking hormonal drugs), the number of abortions and the distribution principle of TCM syndromes in early threatened abortion complicated with subchorionic hematoma(including blood stasis syndrome, dampness and heat syndrome, yin deficiency and blood heat syndrome,blood heat syndrome, qi and blood deficiency syndrome,kidney qi deficiency syndrome) were compared between the two groups. Results The negative life habits in the study group were significantly more than those in the control group(P<0.05); the number of abortions in the study group was significantly different from that in the control group( P<0.05);there was statistically significant differences in the distribution principle of TCM syndromes in the patients with early threatened abortion complicated with subchorionic hematoma in different gestational weeks(P<0.05). Conclusion The negative life habits and frequency of abortion are the main influencing factors for early threatened abortion complicated with subchorionic hematoma; there is a close relationship between the gestational weeks of pregnant women and the distribution of TCM syndromes in early threatened abortion complicated with subchorionic hematoma. The kidney qi deficiency syndrome is the main syndrome type of early threatened abortion complicated with subchorionic hematoma.
引文
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[18] Petruzziello A,Coppola N,Loquercio G,et al. Distribution pattern of hepatitis C virus genotypes and correlation with viral load and risk factors in chronic positive patients[J]. Intervirology,2016,57(6):311-318.
[19]黄烨,陈纬,刁军成.Ca125、HCG、P对早期先兆流产患者妊娠结局预测的比较[J].重庆医科大学学报,2016,9(3):253-256.
[20]余佩琳,王俊玲,李亚,等.寿胎丸加味方治疗先兆流产合并宫腔积血的临床观察[J].中国实验方剂学杂志,2017,26(3):155-158.
[2] Colferai AS,Silvafilho RP,Martins AM,et al.Distribution pattern of anthropogenic marine debris along the gastrointestinal tract of green turtles(Chelonia mydas)as implications for rehabilitationJ]. Marine Pollution Bulletin,2017,119(1):231-237.
[3]李清,朱瑾,华克勤.绒毛膜下血肿孕妇妊娠结局的荟萃分析[J].中华医学杂志,2016,96(17):1383-1385.
[4] Deng J,Li X,Jin J,et al. Distribution pattern of choroidal thickness at the posterior pole in Chinese children with myopia[J]. Investigative Ophthalmology&Visual Science,2018,59(3):1577.
[5]王丽梅,张建亚,王利红,等.滋阴养胎方对先兆流产患者Th1/Th2细胞因子平衡状况的影响[J].中国中西医结合杂志,2016,36(12):1524-1526.
[6] Kono Y,Sasaki H,Kurihara Y,et al. Distribution pattern of Polar cod(Boreogadus saida)larvae and larval fish assemblages in relation to oceanographic parameters in the northern Bering Sea and Chukchi Sea[J].Polar Biology,2016,39(6):1039-1048.
[7]丁琅娟,程芙蓉.中西医结合对先兆流产早期患者的疗效及妊娠结局的影响分析[J].中华中医药学刊,2017,36(5):1342-1344.
[8]田春漫,陈波.固肾安胎丸联用黄体酮对先兆流产患者血清β-HCG,P,E2和CA125水平的影响[J].中国中药杂志,2016,41(2):321-325.
[9] Haueis SA,Kr覿nzlin P,Mangana J,et al. Does the distribution pattern of brain metastases during BRAF inhibitor therapy reflect phenotype switching?[J]. Melanoma Research,2017,27(3):231.
[10]高学军,叶春花,赵会荣,等.延续精准护理对高龄早期先兆流产患者妊娠结局的影响分析[J].中国地方病防治杂志,2017,13(8):947-947.
[11] Ruber J,Geist J,Hartmann M,et al.Spatio-temporal distribution pattern of the picocyanobacterium Synechococcus,in lakes of different trophic states:A comparison of flow cytometry and sequencing approaches[J]. Hydrobiologia,2018,63(1):1-16.
[12]高飞霞,巫海旺,郜洁,等.寿胎丸治疗先兆流产:随机对照试验的Meta分析[J].中华中医药学刊,2016,12(11):2637-2642.
[13] Renan S,Gafny S,Perl RGB,et al. Living quarters of a living fossil-Uncovering the current distribution pattern of the rediscovered Hula painted frog(Latonia nigriventer)using environmental DNA[J].Molecular Ecology,2017,26(24):6801.
[14]杨海波,杨太珠,罗红.超声联合MRI诊断巨大绒毛膜下血肿伴副胎盘1例[J].中国超声医学杂志,2016,32(6):575-575.
[15] Luo FangLi,Huang Lin,Lei Ting,et al. Responsiveness of performance and morphological traits to experimental submergence predicts field distribution pattern of wetland plants[J].Journal of Vegetation Science,2016,27(2):340-351.
[16]唐培培,谈勇.多囊卵巢综合征中医证型分布规律及性激素水平、糖代谢特点[J].中国中西医结合杂志,2016,36(7):801-805.
[17]艳秋,侯丽辉,高金金,等.多囊卵巢综合征中医证型分布规律及血清性激素、糖代谢特点的研究[J].中华中医药学刊,2016,30(3):579-582.
[18] Petruzziello A,Coppola N,Loquercio G,et al. Distribution pattern of hepatitis C virus genotypes and correlation with viral load and risk factors in chronic positive patients[J]. Intervirology,2016,57(6):311-318.
[19]黄烨,陈纬,刁军成.Ca125、HCG、P对早期先兆流产患者妊娠结局预测的比较[J].重庆医科大学学报,2016,9(3):253-256.
[20]余佩琳,王俊玲,李亚,等.寿胎丸加味方治疗先兆流产合并宫腔积血的临床观察[J].中国实验方剂学杂志,2017,26(3):155-158.