赵宗江教授治疗糖尿病肾病的学术思想及临床经验撷英
|
摘要
糖尿病肾病是现代社会高发而又难治的疾病之一。防治该病和延缓其病程进展是现代医学研究的热点、难点。赵宗江教授多年从事中西医结合肾病临床及研究工作,对慢性肾脏病的中西医诊疗方面造诣颇深,对糖尿病肾病中医理、法、方、药也有独到见解,临床经验丰富、用药合理、疗效显著。本文在赵宗江教授的悉心指导下,从"肾痿"入手,结合赵宗江教授大量的研究成果,探讨赵宗江教授治疗该病的学术观点及临床经验,以供同道参考。
Diabetic nephropathy was one of the diseases with high incidence and difficult to treat in modern society. Modern medicine had focused on the prevention and treatment of this difficult disease to delay its development. Professor Zhao Zongjiang, who had been working on the treatment of kidney diseases with traditional Chinese medicine(TCM) and modern medicine for many years, had deep understanding on integrative medicine treatment of chronic kidney diseases(CKD), diabetic nephropathy treatment with unique TCM principles, methods, prescriptions and herbs, with rich clinical experiences, rational medication and significant therapeutic effects. Under the guidance of professor Zhao Zongjiang, this article started with consumptive kidney disease in combination with a large amount of professor Zhao Zongjiang's research results, for the discussion of professor Zhao Zongjiang's academic thoughts and clinical experiences in disease treatment to provide references in this field.
Diabetic nephropathy was one of the diseases with high incidence and difficult to treat in modern society. Modern medicine had focused on the prevention and treatment of this difficult disease to delay its development. Professor Zhao Zongjiang, who had been working on the treatment of kidney diseases with traditional Chinese medicine(TCM) and modern medicine for many years, had deep understanding on integrative medicine treatment of chronic kidney diseases(CKD), diabetic nephropathy treatment with unique TCM principles, methods, prescriptions and herbs, with rich clinical experiences, rational medication and significant therapeutic effects. Under the guidance of professor Zhao Zongjiang, this article started with consumptive kidney disease in combination with a large amount of professor Zhao Zongjiang's research results, for the discussion of professor Zhao Zongjiang's academic thoughts and clinical experiences in disease treatment to provide references in this field.
引文
1赵宗江,豆小妮,张新雪.糖尿病肾病“肾痿”假说探讨.中医杂志,2011,52:8-10.
2周仲瑛.中医内科学.北京:中国中医药出版社,2005:427-433.
3豆小妮.糖尿病肾病“肾痿”假说的建立及其糖肾平胶囊对结缔组织生长因子调控机制的研究.北京:北京中医药大学,硕士研究生学位论文,2009:10-16.
4赵宗江,王颖超,杜磊,等.健脾益肾化瘀通络方对糖尿病肾病大鼠氧化应激的影响.北京中医药大学学报,2013,36(3):161-166.
5王颖超.基于“肾痿”假说的糖肾平对DKD大鼠肾脏保护作用及对PI3K及AKT信号转导通路影响的研究.北京:北京中医药大学,硕士研究生学位论文,2014:14-17.
6高晓村.葛根芩连汤合程氏萆薢分清饮加减治疗湿热型糖尿病肾病的疗效观察.北京中医药,2009,28(9):718-719.
7赵宗江,豆小妮,张新雪,等.糖肾平胶囊对糖尿病肾病大鼠肾脏保护作用及其对肾组织TGF-β_1蛋白及mRNA表达的影响.世界科学技术-中医药现代化,2010,12(5):759-763.
8赵敬,王颖超,赵宗江,等.糖肾平通过TGF-β_1-Smad2/3-ILK信号通路干预高糖+LPS诱导足细胞上皮间质转分化的分子机制研究.中国中西医结合肾病杂志,2014,15(5):392-396.
9杜磊,赵敬,赵宗江,等.糖肾平对高糖+LPS刺激足细胞TGF-β_1/Smad7信号转导通路影响的研究.中国中西医结合肾病杂志,2013,14(2):107-110.
10冯丽园.糖肾宁胶囊对糖尿病肾病大鼠肾脏保护作用及其对TGF-β_1/Smad7信号通路影响的实验研究.北京:北京中医药大学,硕士研究生学位论文,2010:48-55.
11施鹏,赵宗江,张新雪,等.糖肾宁对糖尿病大鼠的肾脏保护作用及其对TGF-β_1/Smad7信号转导通路的影响.中华中医药杂志,2013,28(5):1436-1440.
12张卓,王光权,朱飞跃,等.影响早期糖尿病肾病预后危险因素探讨分析.现代生物医学进展,2011,11(16):3131-3165.
2周仲瑛.中医内科学.北京:中国中医药出版社,2005:427-433.
3豆小妮.糖尿病肾病“肾痿”假说的建立及其糖肾平胶囊对结缔组织生长因子调控机制的研究.北京:北京中医药大学,硕士研究生学位论文,2009:10-16.
4赵宗江,王颖超,杜磊,等.健脾益肾化瘀通络方对糖尿病肾病大鼠氧化应激的影响.北京中医药大学学报,2013,36(3):161-166.
5王颖超.基于“肾痿”假说的糖肾平对DKD大鼠肾脏保护作用及对PI3K及AKT信号转导通路影响的研究.北京:北京中医药大学,硕士研究生学位论文,2014:14-17.
6高晓村.葛根芩连汤合程氏萆薢分清饮加减治疗湿热型糖尿病肾病的疗效观察.北京中医药,2009,28(9):718-719.
7赵宗江,豆小妮,张新雪,等.糖肾平胶囊对糖尿病肾病大鼠肾脏保护作用及其对肾组织TGF-β_1蛋白及mRNA表达的影响.世界科学技术-中医药现代化,2010,12(5):759-763.
8赵敬,王颖超,赵宗江,等.糖肾平通过TGF-β_1-Smad2/3-ILK信号通路干预高糖+LPS诱导足细胞上皮间质转分化的分子机制研究.中国中西医结合肾病杂志,2014,15(5):392-396.
9杜磊,赵敬,赵宗江,等.糖肾平对高糖+LPS刺激足细胞TGF-β_1/Smad7信号转导通路影响的研究.中国中西医结合肾病杂志,2013,14(2):107-110.
10冯丽园.糖肾宁胶囊对糖尿病肾病大鼠肾脏保护作用及其对TGF-β_1/Smad7信号通路影响的实验研究.北京:北京中医药大学,硕士研究生学位论文,2010:48-55.
11施鹏,赵宗江,张新雪,等.糖肾宁对糖尿病大鼠的肾脏保护作用及其对TGF-β_1/Smad7信号转导通路的影响.中华中医药杂志,2013,28(5):1436-1440.
12张卓,王光权,朱飞跃,等.影响早期糖尿病肾病预后危险因素探讨分析.现代生物医学进展,2011,11(16):3131-3165.