以症状为基础的程序化治疗方案对亚急性、慢性咳嗽的临床有效性研究
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摘要
目的探讨以临床症状为基础的程序化治疗方案对亚急性、慢性咳嗽患者的有效性。方法将56例亚急性、慢性咳嗽患者随机分为试验组和对照组各28例。试验组采用以临床指南制定《以症状为基础的亚急性、慢性程序化治疗方案评估表》进行临床症状评估后,针对指向病因进行治疗,对照组给予经验治疗,以"咳嗽症状积分表"对两组患者的临床疗效进行评估,比较两组咳嗽症状评分、临床有效性评价、安全性评价。结果治疗后,试验组夜间和全日咳嗽症状积分中位数均低于对照组(P<0.05)。治疗2周后,试验组有效率为89.29%,高于对照组的52.17%,差异有统计学意义(P<0.05)。结论以症状为基础程序化治疗对于亚急性、慢性咳嗽的临床疗效优于简单的经验性治疗。
Objective To investigate the effectiveness of clinical symptom-based programmed treatment regimens in patients with sub acute and chronic cough. Methods 56 patients with subacute and chronic cough were randomly divided into the experimental group and the control group, 28 cases each. The experimental group used the clinical guidelines to develop a "symptom-based sub acute, chronic programmed treatment evaluation form" for clinical symptom evaluation, for the treatment of the cause of the disease, the control group was given experience and treatment, with the "cough symptom score table" The clinical efficacy of the two groups of patients was evaluated, and the scores of cough symptoms, clinical efficacy evaluation, and safety evaluation were compared between the two groups. Results After treatment, the median scores of nighttime and total cough symptoms in the experimental group were lower than those in the control group(P <0.05). After 2 weeks of treatment, the effective rate of the experimental group was 89.29%, which was higher than that of the control group 52.17%,the difference was statistically significant( P <0.05).Conclusion The clinical efficacy of symptom-based programmed therapy for sub acute and chronic cough is superior to simple empirical treatment.
Objective To investigate the effectiveness of clinical symptom-based programmed treatment regimens in patients with sub acute and chronic cough. Methods 56 patients with subacute and chronic cough were randomly divided into the experimental group and the control group, 28 cases each. The experimental group used the clinical guidelines to develop a "symptom-based sub acute, chronic programmed treatment evaluation form" for clinical symptom evaluation, for the treatment of the cause of the disease, the control group was given experience and treatment, with the "cough symptom score table" The clinical efficacy of the two groups of patients was evaluated, and the scores of cough symptoms, clinical efficacy evaluation, and safety evaluation were compared between the two groups. Results After treatment, the median scores of nighttime and total cough symptoms in the experimental group were lower than those in the control group(P <0.05). After 2 weeks of treatment, the effective rate of the experimental group was 89.29%, which was higher than that of the control group 52.17%,the difference was statistically significant( P <0.05).Conclusion The clinical efficacy of symptom-based programmed therapy for sub acute and chronic cough is superior to simple empirical treatment.
引文
[1]中华医学会呼吸病学分会哮喘学组.咳嗽的诊断与治疗指南(2015)[J].中华结核和呼吸杂志,2016, 39(5):323.
[2]Ojoo JC,Everett CF,Mulrennan SA,et al.Management of patients with chronic cough using a clinical protocol:a prospective observational study[J].Cough,2013,9(2):9974-9979.
[3]Benich JJ 3rd,Carek PJ.Evaluation of the patient with chronic cough[J]. Am Fam Physician,2011,84(8):887-892.
[4]Pacheco A,Cobeta I,Wagner C.Refractory chronic cough:new perspectives in diagnosis and treatment[J].Archivos de Bronconeumología,2013,49(4):151-157.
[5]江梅,廖理粤,罗炜,等.国内咳嗽诊疗指南的质量评价[J].中国循证医学杂志,2015,15(4):409-413.
[6]李丽.慢性咳嗽诊治的研究进展[J].中国医药指南,2015,13(7):61-62.
[7]赖克方.慢性咳嗽病因分布及诊断思路[J].中国临床医生,2014(7):1-4.
[8]姜淑娟.慢性咳嗽指南解读[J].临床内科杂志,2015(2):142-143.
[2]Ojoo JC,Everett CF,Mulrennan SA,et al.Management of patients with chronic cough using a clinical protocol:a prospective observational study[J].Cough,2013,9(2):9974-9979.
[3]Benich JJ 3rd,Carek PJ.Evaluation of the patient with chronic cough[J]. Am Fam Physician,2011,84(8):887-892.
[4]Pacheco A,Cobeta I,Wagner C.Refractory chronic cough:new perspectives in diagnosis and treatment[J].Archivos de Bronconeumología,2013,49(4):151-157.
[5]江梅,廖理粤,罗炜,等.国内咳嗽诊疗指南的质量评价[J].中国循证医学杂志,2015,15(4):409-413.
[6]李丽.慢性咳嗽诊治的研究进展[J].中国医药指南,2015,13(7):61-62.
[7]赖克方.慢性咳嗽病因分布及诊断思路[J].中国临床医生,2014(7):1-4.
[8]姜淑娟.慢性咳嗽指南解读[J].临床内科杂志,2015(2):142-143.