白内障超声乳化术对糖尿病性白内障患者角膜内皮细胞的影响
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摘要
目的探讨白内障超声乳化术对糖尿病性白内障患者角膜内皮细胞的影响。方法将我院收治的104例白内障患者根据疾病类型不同分为观察组(53例,糖尿病性白内障患者)和对照组(51例,单纯老年性白内障患者),两组患者均实施白内障超声乳化术。比较两组患者治疗前、后角膜内皮细胞相关指标。结果治疗后7、42、60 d,观察组泪膜破裂时间、基础泪液分泌试验结果均明显低于对照组,差异具有统计学意义(P<0.05)。治疗后7 d,观察组角膜内皮细胞密度明显低于对照组,中央角膜厚度明显厚于对照组,差异具有统计学意义(P<0.05)。结论白内障超声乳化术会严重影响糖尿病性白内障患者的角膜内皮细胞,这主要与其手术耐受性低有关,提示眼科医师应在术后及时改善患者的角膜内皮及眼表面组织功能。
Objective To investigate the effect of phacoemulsification on corneal endothelial cells in patients with diabetic cataract. Methods A total of 104 cases of cataract patients admitted in our hospital were divided into observation group(53 cases, diabetic cataract patients) and control group(51 cases, simple senile cataract patients) according to different types of disease. Both groups were treated with phacoemulsification. The related indicators of corneal endothelial cells were compared between the two groups before and after treatment. Results At 7, 42 and 60 days after treatment, the tear film rupture time and basic tear secretion test results in the observation group were significantly lower than those in the control group, and the differences were statistically significant(P <0.05). At 7 days after treatment, the corneal endothelial cells density of the observation group was significantly lower than that of the control group, and the central corneal thickness was significantly thicker than that of the control group, and the differences were statistically significant(P <0.05). Conclusion Phacoemulsification can seriously affect corneal endothelial cells in patients with diabetic cataract,which is mainly related to the low tolerance of surgery in patients. It is suggested that ophthalmologists should improve corneal endothelium and ocular surface tissue function in patients with diabetic cataract in time after surgery.
Objective To investigate the effect of phacoemulsification on corneal endothelial cells in patients with diabetic cataract. Methods A total of 104 cases of cataract patients admitted in our hospital were divided into observation group(53 cases, diabetic cataract patients) and control group(51 cases, simple senile cataract patients) according to different types of disease. Both groups were treated with phacoemulsification. The related indicators of corneal endothelial cells were compared between the two groups before and after treatment. Results At 7, 42 and 60 days after treatment, the tear film rupture time and basic tear secretion test results in the observation group were significantly lower than those in the control group, and the differences were statistically significant(P <0.05). At 7 days after treatment, the corneal endothelial cells density of the observation group was significantly lower than that of the control group, and the central corneal thickness was significantly thicker than that of the control group, and the differences were statistically significant(P <0.05). Conclusion Phacoemulsification can seriously affect corneal endothelial cells in patients with diabetic cataract,which is mainly related to the low tolerance of surgery in patients. It is suggested that ophthalmologists should improve corneal endothelium and ocular surface tissue function in patients with diabetic cataract in time after surgery.
引文
[1]张玲玲,贾义军,郑广瑛.非球面散光矫正型多焦点人工晶状体植入术对白内障患者视力和对比敏感度的影响[J].国际眼科杂志,2016,16(7):1302-1305.
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[9]魏荫娟,宋慧,汤欣.光学质量分析系统对不同材质和屈光指数的IOL植入眼视觉质量的评估[J].中华实验眼科杂志,2016,34(3):248-253.
[10]徐雯,郦舒伊.加强对白内障手术的综合认识和管理提高白内障的诊疗水平[J].中华实验眼科杂志,2016,34(3):193-198.
[11]林志博,黄芳,潘安鹏,等.区域折射型多焦点人工晶状体植入术后视觉质量的临床研究[J].中华眼视光学与视觉科学杂志,2017,19(8):482-487.
[12]宫贤惠,叶凌颖,林志博,等.+3.00 D和+2.50 D近附加度数多焦点人工晶状体植入术后视觉质量比较[J].中华眼视光学与视觉科学杂志,2017,19(10):606-612.
[13]楚妙,巨朝娟,梅文华,等.白内障超声乳化联合前部玻璃体切除术后睫状沟植入Toric散光晶状体效果观察[J].山东医药,2016,56(10):92-93.
[14]朱冉,程蕾,龙克利,等.波前像差引导的飞秒制瓣LASIK术后角膜后表面形态和高阶像差的变化[J].徐州医学院学报,2015,35(1):49-52.
[15]惠娜,喻磊,王从毅,等.同轴微切口白内障超声乳化吸除术对角膜散光影响研究[J].陕西医学杂志,2016,45(11):1468-1471.
[2]李凤至,杨欣,吴利安,等.白内障超声乳化并散光矫正型多焦点人工晶体植入的疗效分析[J].广西医科大学学报,2017,34(10):1526-1529.
[3]贝政平,舒怀,周梁.眼、耳鼻咽喉科疾病诊断标准[M].北京:科学出版社,2007.
[4]陈拥军,姬亚洲,毋艳君,等.长眼轴合并角膜散光的白内障患者植入散光矫正型人工晶状体的临床观察[J].国际眼科杂志,2016,16(3):443-445.
[5]雷新平,宋晓鹃,单武强.角膜切口白内障手术对患者术后角膜屈光度及视觉质量的影响研究[J].临床眼科杂志,2016,24(3):196-199.
[6]杨苗苗,王帅,王文战.1型与2型糖尿病并发增生型糖尿病视网膜病变患者的眼生物学测量值比较[J].眼科新进展,2017,37(4):362-364.
[7]宋凡倩,高宁宁,葛红岩.BIGH3基因在角膜疾病及糖尿病视网膜病变中的研究新进展[J].国际眼科杂志,2017,17(3):449-450.
[8]马瑶,马忠旭,高原,等.高阶像差及散射光对非球面IOL眼视网膜成像质量的影响[J].中华实验眼科杂志,2016,34(3):254-259.
[9]魏荫娟,宋慧,汤欣.光学质量分析系统对不同材质和屈光指数的IOL植入眼视觉质量的评估[J].中华实验眼科杂志,2016,34(3):248-253.
[10]徐雯,郦舒伊.加强对白内障手术的综合认识和管理提高白内障的诊疗水平[J].中华实验眼科杂志,2016,34(3):193-198.
[11]林志博,黄芳,潘安鹏,等.区域折射型多焦点人工晶状体植入术后视觉质量的临床研究[J].中华眼视光学与视觉科学杂志,2017,19(8):482-487.
[12]宫贤惠,叶凌颖,林志博,等.+3.00 D和+2.50 D近附加度数多焦点人工晶状体植入术后视觉质量比较[J].中华眼视光学与视觉科学杂志,2017,19(10):606-612.
[13]楚妙,巨朝娟,梅文华,等.白内障超声乳化联合前部玻璃体切除术后睫状沟植入Toric散光晶状体效果观察[J].山东医药,2016,56(10):92-93.
[14]朱冉,程蕾,龙克利,等.波前像差引导的飞秒制瓣LASIK术后角膜后表面形态和高阶像差的变化[J].徐州医学院学报,2015,35(1):49-52.
[15]惠娜,喻磊,王从毅,等.同轴微切口白内障超声乳化吸除术对角膜散光影响研究[J].陕西医学杂志,2016,45(11):1468-1471.