基于因子分析诱导排卵失败不孕症的证型分布规律
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摘要
目的:探讨尿促性腺激素(HMG)诱导排卵失败不孕症的中医证型分布规律。方法:采集250例接受HMG诱导排卵治疗的不孕症患者的症状、舌象、脉象等四诊信息,本项课题研究只针对其中180例诱导失败患者的四诊信息进行因子分析。结果:诱导排卵失败患者的中医证型多为阴虚内热型、热盛津伤型和肝郁化热型,其中阴虚内热型对失败组的贡献率最大,而热盛津伤型的发生频率最高。结论:通过对诱导排卵失败组中医证型分布规律的研究,为诱导排卵失败后选择最佳的中医后续治疗方案提供证候学依据和辨证思路。
Objective:To investigate the distribution of TCM syndrome types in ovulation failure infertility induced by urine gonadotropin(HMG).Methods:The four diagnostic information of 250 cases of infertility treated with HMG induced ovulation were collected,and the factors of the four diagnostic information of 180 cases were analyzed.Results:The syndrome types of induced ovulation failure were yin deficiency and internal heat type,heat-sheng-Jin injury type and liver depression and heat type,among which yin deficiency and internal heat type contributed most to the failure group,while heat-sheng-Jin injury type occurred most frequently.Conclusion:Through the study of the distribution of TCM syndrome types in the group of induced ovulation failure,it can provide the evidence and dialectical thinking for selecting the best follow-up treatment plan of TCM after induced ovulation failure.human menopausal gonadotrophin,
Objective:To investigate the distribution of TCM syndrome types in ovulation failure infertility induced by urine gonadotropin(HMG).Methods:The four diagnostic information of 250 cases of infertility treated with HMG induced ovulation were collected,and the factors of the four diagnostic information of 180 cases were analyzed.Results:The syndrome types of induced ovulation failure were yin deficiency and internal heat type,heat-sheng-Jin injury type and liver depression and heat type,among which yin deficiency and internal heat type contributed most to the failure group,while heat-sheng-Jin injury type occurred most frequently.Conclusion:Through the study of the distribution of TCM syndrome types in the group of induced ovulation failure,it can provide the evidence and dialectical thinking for selecting the best follow-up treatment plan of TCM after induced ovulation failure.human menopausal gonadotrophin,
引文
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[3]罗世芳.排卵障碍性不孕症诊断及治疗.北京:中国医药科技出版社,1997:30-34
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[6]王永炎,张志斌.再议完善辨证方法体系的几个问题.天津中医药,2007,24(1):1-4
[7]苏泽琦,张雨珊,王文君,等.基于因子分析优化方案及复杂系统熵聚类的慢性萎缩性胃炎的证候分类研究.中华中医药杂志,2016,31(5):1836-1839
[8]王丽颖,李元,宇文亚,等.基于因子分析探讨高血压中医证候要素研究.中华中医药杂志,2013,28(12):3520-3522
[9]张允岭,陈宝鑫,金香兰,等.基于因子分析的血管源性轻度认知障碍证候要素提取及分布研究.中华中医药杂志,2013,28(9):2596-2600
[10]何羿婷,查青林,阎小萍,等.类分湿关节炎症状因子分析及其与疗效的关系.中国中西医结合杂志,2005,25(12):1077-1081
[11]王晓戎,袁孝兵,储慧琴,等.因子分析和聚类分析联合应用在大肠癌证候分布中的研究.时珍国医国药.2012,23(5):1194-1195
[12]李毅,张小萍.消化性溃疡中医症候因子分析.时珍国医国药.2010,12(21):3379-3380
[13]陈聪,宋咏梅.失眠症中医证候的聚类分析及因子分析研究.时珍国医国药,2014,11(25):2811-2812
[14]陈松鹤,王云涛,马建新,等.冬季生活方式对诱导排卵疗效的影响.医学研究与教育,2011,28(3):55-58
[15]崔芳,邵雪艳,郭鹏波,等.王希浩教授浩疗排巧障碍性不孕症经验.光明中医,2011,26(5):896-897
[16]刘敏如,谭万信.中医妇产科学.2版.北京:人民卫生出版社,2011:742
[17]李灿东,高碧珍,黄熙理,等.不孕症肝郁病理与性腺轴功能变化的相关性研究.上海中医药大学学报,2005,19(3):36-38
[18]王桂枝,李凤仙,赵韶星.中药人工周期疗法治疗不孕症135例.中医药研究,1997,13(4):17-18
[19]王兆芬.中药治巧排卵障碍性不孕症62例.长春中医药大学学报,2009,25(4):571-572
[20]夏桂成.夏桂成实用中医妇科学.北京:中国中医药出版社,2009:482-496
[21]夏桂成.中医妇科理论与实践.北京:人民卫生出版社,2003:401
[22]池雷.夏桂成教授调周疗法治疗月经病述要.实用医技杂志,2008,15(33):4914
[2]葛秦生,连丽娟.生殖内分泌与妇科疾病诊治手册.北京:科学技术文献出版社,2002:543
[3]罗世芳.排卵障碍性不孕症诊断及治疗.北京:中国医药科技出版社,1997:30-34
[4]国家技术监督局.GB/T16751.2-1997《中医临床诊疗术语》.北京:中国标准出版社,1997:30-34
[5]郭蕾,王永炎,张志斌.关于证候概念的诠释.北京中医药大学学报,2003,26(2):5-8
[6]王永炎,张志斌.再议完善辨证方法体系的几个问题.天津中医药,2007,24(1):1-4
[7]苏泽琦,张雨珊,王文君,等.基于因子分析优化方案及复杂系统熵聚类的慢性萎缩性胃炎的证候分类研究.中华中医药杂志,2016,31(5):1836-1839
[8]王丽颖,李元,宇文亚,等.基于因子分析探讨高血压中医证候要素研究.中华中医药杂志,2013,28(12):3520-3522
[9]张允岭,陈宝鑫,金香兰,等.基于因子分析的血管源性轻度认知障碍证候要素提取及分布研究.中华中医药杂志,2013,28(9):2596-2600
[10]何羿婷,查青林,阎小萍,等.类分湿关节炎症状因子分析及其与疗效的关系.中国中西医结合杂志,2005,25(12):1077-1081
[11]王晓戎,袁孝兵,储慧琴,等.因子分析和聚类分析联合应用在大肠癌证候分布中的研究.时珍国医国药.2012,23(5):1194-1195
[12]李毅,张小萍.消化性溃疡中医症候因子分析.时珍国医国药.2010,12(21):3379-3380
[13]陈聪,宋咏梅.失眠症中医证候的聚类分析及因子分析研究.时珍国医国药,2014,11(25):2811-2812
[14]陈松鹤,王云涛,马建新,等.冬季生活方式对诱导排卵疗效的影响.医学研究与教育,2011,28(3):55-58
[15]崔芳,邵雪艳,郭鹏波,等.王希浩教授浩疗排巧障碍性不孕症经验.光明中医,2011,26(5):896-897
[16]刘敏如,谭万信.中医妇产科学.2版.北京:人民卫生出版社,2011:742
[17]李灿东,高碧珍,黄熙理,等.不孕症肝郁病理与性腺轴功能变化的相关性研究.上海中医药大学学报,2005,19(3):36-38
[18]王桂枝,李凤仙,赵韶星.中药人工周期疗法治疗不孕症135例.中医药研究,1997,13(4):17-18
[19]王兆芬.中药治巧排卵障碍性不孕症62例.长春中医药大学学报,2009,25(4):571-572
[20]夏桂成.夏桂成实用中医妇科学.北京:中国中医药出版社,2009:482-496
[21]夏桂成.中医妇科理论与实践.北京:人民卫生出版社,2003:401
[22]池雷.夏桂成教授调周疗法治疗月经病述要.实用医技杂志,2008,15(33):4914