MR半傅立叶单次激发快速自旋回波序列与超声检查在胎儿颅脑疾病的对比分析
|
摘要
目的探讨MR半傅立叶单次激发快速自旋回波序列(half-Fourier acquisition single-shot turbo spin-echo,HASTE)在胎儿颅脑疾病的应用价值。材料与方法选取超声诊断或疑诊胎儿颅脑发育异常孕妇46例,应用HASTE序列对胎儿头颅行轴面、冠状及矢状面扫描,对两种方法诊断结果进行对比分析。结果超声提出诊断34例,疑诊病变12例。HASTE共发现病变35例,检出病变45个。超声在液性病变诊断方面,在测量异常值≥3 mm时,诊断侧脑室扩张及枕大池增宽与HASTE符合率达96%(26/27);在超声测量异常值<3 mm时,诊断侧脑室扩张及枕大池增宽与HASTE符合率为25%(3/12)。在诊断中线结构病变及复杂颅内病变方面,HASTE序列显示病变数明显多于超声检查。结论 HASTE序列在胎儿颅脑产前诊断中可进一步验证或修正超声诊断,且在颅脑中线结构及脑实质病变方面诊断明显优于超声检查。
Objective:To explore the clinical application of half-Fourier acquisition single-shot turbo spin-echo(HASTE) sequence of MRI examination for fetal brain diseases.Materials and Methods:Forty-six cases of pregnant women with ultrasonic diagnosis as diseases or suspected with disease in fetal brain were performed with HASTE sequence scanning by axial view,sagittal view and coronal view.A comparative analysis was performed between the results of HASTE sequence and the results of ultrasound diagnosis.Results:Of the 46 cases,34 were diagnosed with specific diseases and 12 suspected with abnormal fetal brain by the ultrasonic examination,while 35 cases with 45 specific conditions were found by HASTE sequence and 11 found without abnormal signs.For the liquid lesions,there was a good consistency,96%(26/27),between ultrasonic examination and HASTE sequence in the group of the lesions ≥3 mm,while only 25%(3/12) consistence was found between ultrasonic examination and HASTE sequence in the group of the lesions <3 mm.For the craniocerebral midline structure diseases and complex intracranial diseases,HASTE sequence was proved to be significantly better than those of ultrasonic examination.Conclusions:HASTE sequence is proved to be a potential tool for validating or correcting the ultrasonic diagnosis in the fetal brain diseases,and is found to be significantly better than ultrasound for the craniocerebral midline structure lesions and parenchymal diseases.
Objective:To explore the clinical application of half-Fourier acquisition single-shot turbo spin-echo(HASTE) sequence of MRI examination for fetal brain diseases.Materials and Methods:Forty-six cases of pregnant women with ultrasonic diagnosis as diseases or suspected with disease in fetal brain were performed with HASTE sequence scanning by axial view,sagittal view and coronal view.A comparative analysis was performed between the results of HASTE sequence and the results of ultrasound diagnosis.Results:Of the 46 cases,34 were diagnosed with specific diseases and 12 suspected with abnormal fetal brain by the ultrasonic examination,while 35 cases with 45 specific conditions were found by HASTE sequence and 11 found without abnormal signs.For the liquid lesions,there was a good consistency,96%(26/27),between ultrasonic examination and HASTE sequence in the group of the lesions ≥3 mm,while only 25%(3/12) consistence was found between ultrasonic examination and HASTE sequence in the group of the lesions <3 mm.For the craniocerebral midline structure diseases and complex intracranial diseases,HASTE sequence was proved to be significantly better than those of ultrasonic examination.Conclusions:HASTE sequence is proved to be a potential tool for validating or correcting the ultrasonic diagnosis in the fetal brain diseases,and is found to be significantly better than ultrasound for the craniocerebral midline structure lesions and parenchymal diseases.
引文
[1]Sun T,Shi YL,Han SQ et al.Application of SSFSE sequence in fetal central nervous system.China Med devic,2007,27(7):165-167.孙涛,石银龙,韩善清.SSFSE序列在胎儿中枢神经系统MRI检查中的应用.中国医疗设备,2007,27(7):165-167.
[2]Wedegartner U,Kooijman H,Andreas T,et al.T2 and T2*measurements of fetal brain oxygenation during hypoxia with MRI at 3T:correlation with fetal arterial blood oxygen saturation.Eur J Radiol,2010,20(1):121-127.
[3]Saleem SN.Fetal magnetic resonance imaging(MRI):a tool for a better understanding of normal and abnormal brain development.J Child Neurol,2013,28(7):890-908.
[4]Pugash D,Brugger PC,Bettelheim D,et al.Prenatal ultrasound and fetal MRI:the comparative value of each modality in prenatal diagnosis.Eur J Radiol,2008,68(2):214-226.
[5]Zhu M.Fetal MR imaging:a new clinical application.Chin J Magn Reson Imaging,2011,2(1):7-12.朱铭.胎儿磁共振-磁共振检查的新领域.磁共振成像,2011,2(1):7-12.
[6]Dong SZ,Zhu M,Zhong YM,et al.MRI diagnosis of fetal corpus callosum agenesis.Chin J Magn Reson Imaging,2011,2(1):42-46.董素贞,朱铭,钟玉敏,等.胎儿胼胝体发育不全的MRI诊断.磁共振成像,2011,2(1):42-46.
[7]Jiang XL,Deng XD,Li XB,et al.Comparison of ultrasound and MRI in the prenatal diagnosis of agenesis of corpus callosum.Chin J Med Imaging Technol,2011,27(2):357-360.姜小力,邓学东,李晓兵.胎儿胼胝体发育不良的超声和磁共振对比观察.中国医学影像技术,2011,27(2):357-360.
[8]Tang PH,Bartha AI,Norton ME,et al.Agenesis of the corpus callosum:an MR imaging analysis of associated abnormalities in the fetus.AJNR Am J Neuroradiol,2009,30(2):257-263.
[9]Prayer D,Brugger PC,Kasprian G,et al.MRI of fetal acquired brain lesions.Eur J Radiol,2006,57(2):233-249.
[10]Pang Y,Xia LM,Sun ZY,et al.3D MRI investigation on fetal surface malformations.Ch in J Magn Reson Imaging,2012,3(3):194-199.庞颖,夏黎明,孙子燕,等.3D MRI诊断胎儿体表畸形的研究.磁共振成像,2012,3(3):194-199.
[11]Sun ZY,Xia LM,Wang CY,et al.Three-dimensional MR imaging in detection of congenital malformations of fetal colon.Chin J Magn Reson Imaging,2010,1(6):50-55.孙子燕,夏黎明,王承缘,等.三维磁共振成像在检出胎儿结肠先天异常方面的应用.磁共振成像,2010,1(6):50-55.
[12]Brugger PC,Weber M,Prayer D.Magnetic resonance imaging of the fetal gallbladder and bile.Eur J Radiol,2010,20(12):2862-2869.
[13]Nemec U,Nemec SF,Weber M,et al.Human long bone development in vivo:analysis of the distal femoral epimetaphysis on MR images of fetuses.Radiology,2013,267(2):570-580.
[14]Yang ZY,Feng F,Wang XY.A guide to technique of magnetic resonance imaging.Beijing:People's Military Medical Press,2007:662.杨正汉,冯蓬,王霄英.磁共振成像技术指南.北京:人民军医出版社,2007:662.
[15]Hu LW,Zhu M,Cao HD,et al.The application of fast imaging MRI in fetal examination.Develop Biom Engin,2013,34(4):221-225.胡立伟,朱铭,曹厚德,等.磁共振快速采集技术在胎儿检查中的应用.生物医学工程学进展,2013,34(4):221-225.
[16]Xiao HC,Wu GC,Jing K,et al.Clinical application of HASTE sequence in fetal brain MRI.J Clin Res,2012,29(12):2412-2413.肖怀春,伍光春,金科,等.HASTE序列在胎儿颅脑磁共振成像中的应用价值.医学临床研究,2012,29(12):2412-2413.
[17]Doneda C,Parazzini C,Righini A,et al.Early cerebral lesions in cytomegalovirus infection:prenatal MR imaging.Radiology,2010,255(2):613-621.
[18]Dong SZ,Zhu M.A comparative study for diagnostic value between ultrasonic and MRI in fetal abnormality.Foreign Med Scien Clin Radiol Fasci,2007,30(4):279-283.董素贞,朱铭.胎儿畸形的超声和MRI诊断价值对比.国外医学临床放射学分册,2007,30(4):279-283.
[19]Yang F,Yang TZ,Luo H,et al.Comparative study of ultrasonagraphy and magnetic resonance imaging in midline structure of fetal brain.J sichuan Uni(Med Sci Edi),2012,43(5):720-724.杨帆,杨太珠,红罗,等.超声和核磁共振成像在胎儿脑中线结构检查中的对比研究.四川大学学报(医学版),2012,43(5):720-724.
[2]Wedegartner U,Kooijman H,Andreas T,et al.T2 and T2*measurements of fetal brain oxygenation during hypoxia with MRI at 3T:correlation with fetal arterial blood oxygen saturation.Eur J Radiol,2010,20(1):121-127.
[3]Saleem SN.Fetal magnetic resonance imaging(MRI):a tool for a better understanding of normal and abnormal brain development.J Child Neurol,2013,28(7):890-908.
[4]Pugash D,Brugger PC,Bettelheim D,et al.Prenatal ultrasound and fetal MRI:the comparative value of each modality in prenatal diagnosis.Eur J Radiol,2008,68(2):214-226.
[5]Zhu M.Fetal MR imaging:a new clinical application.Chin J Magn Reson Imaging,2011,2(1):7-12.朱铭.胎儿磁共振-磁共振检查的新领域.磁共振成像,2011,2(1):7-12.
[6]Dong SZ,Zhu M,Zhong YM,et al.MRI diagnosis of fetal corpus callosum agenesis.Chin J Magn Reson Imaging,2011,2(1):42-46.董素贞,朱铭,钟玉敏,等.胎儿胼胝体发育不全的MRI诊断.磁共振成像,2011,2(1):42-46.
[7]Jiang XL,Deng XD,Li XB,et al.Comparison of ultrasound and MRI in the prenatal diagnosis of agenesis of corpus callosum.Chin J Med Imaging Technol,2011,27(2):357-360.姜小力,邓学东,李晓兵.胎儿胼胝体发育不良的超声和磁共振对比观察.中国医学影像技术,2011,27(2):357-360.
[8]Tang PH,Bartha AI,Norton ME,et al.Agenesis of the corpus callosum:an MR imaging analysis of associated abnormalities in the fetus.AJNR Am J Neuroradiol,2009,30(2):257-263.
[9]Prayer D,Brugger PC,Kasprian G,et al.MRI of fetal acquired brain lesions.Eur J Radiol,2006,57(2):233-249.
[10]Pang Y,Xia LM,Sun ZY,et al.3D MRI investigation on fetal surface malformations.Ch in J Magn Reson Imaging,2012,3(3):194-199.庞颖,夏黎明,孙子燕,等.3D MRI诊断胎儿体表畸形的研究.磁共振成像,2012,3(3):194-199.
[11]Sun ZY,Xia LM,Wang CY,et al.Three-dimensional MR imaging in detection of congenital malformations of fetal colon.Chin J Magn Reson Imaging,2010,1(6):50-55.孙子燕,夏黎明,王承缘,等.三维磁共振成像在检出胎儿结肠先天异常方面的应用.磁共振成像,2010,1(6):50-55.
[12]Brugger PC,Weber M,Prayer D.Magnetic resonance imaging of the fetal gallbladder and bile.Eur J Radiol,2010,20(12):2862-2869.
[13]Nemec U,Nemec SF,Weber M,et al.Human long bone development in vivo:analysis of the distal femoral epimetaphysis on MR images of fetuses.Radiology,2013,267(2):570-580.
[14]Yang ZY,Feng F,Wang XY.A guide to technique of magnetic resonance imaging.Beijing:People's Military Medical Press,2007:662.杨正汉,冯蓬,王霄英.磁共振成像技术指南.北京:人民军医出版社,2007:662.
[15]Hu LW,Zhu M,Cao HD,et al.The application of fast imaging MRI in fetal examination.Develop Biom Engin,2013,34(4):221-225.胡立伟,朱铭,曹厚德,等.磁共振快速采集技术在胎儿检查中的应用.生物医学工程学进展,2013,34(4):221-225.
[16]Xiao HC,Wu GC,Jing K,et al.Clinical application of HASTE sequence in fetal brain MRI.J Clin Res,2012,29(12):2412-2413.肖怀春,伍光春,金科,等.HASTE序列在胎儿颅脑磁共振成像中的应用价值.医学临床研究,2012,29(12):2412-2413.
[17]Doneda C,Parazzini C,Righini A,et al.Early cerebral lesions in cytomegalovirus infection:prenatal MR imaging.Radiology,2010,255(2):613-621.
[18]Dong SZ,Zhu M.A comparative study for diagnostic value between ultrasonic and MRI in fetal abnormality.Foreign Med Scien Clin Radiol Fasci,2007,30(4):279-283.董素贞,朱铭.胎儿畸形的超声和MRI诊断价值对比.国外医学临床放射学分册,2007,30(4):279-283.
[19]Yang F,Yang TZ,Luo H,et al.Comparative study of ultrasonagraphy and magnetic resonance imaging in midline structure of fetal brain.J sichuan Uni(Med Sci Edi),2012,43(5):720-724.杨帆,杨太珠,红罗,等.超声和核磁共振成像在胎儿脑中线结构检查中的对比研究.四川大学学报(医学版),2012,43(5):720-724.