针药结合治疗儿童孤独症临床研究
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摘要
目的观察针药结合治疗儿童孤独症的临床疗效。方法采用随机数字表法将92例患儿分为观察组和对照组各46例。对照组予常规康复治疗。观察组在对照组基础上予中药辨证治疗,每日1剂,每日1次,口服;并予针刺治疗,每日1次,每周5次。均3个月为1个疗程,连续治疗2个疗程。评价2组临床疗效,观察2组儿童孤独症行为评定量表(ABC)评分、儿童孤独症评定量表(CARS)评分及不良反应。结果与本组治疗前比较,2组治疗6个月ABC各项评分均降低(P<0.05);2组治疗6个月比较,观察组ABC评分中生活自理、交往、语言、躯体运动及感觉评分均明显低于对照组(P<0.05)。与本组治疗前比较,2组治疗3、6个月CARS评分明显降低(P<0.05);2组治疗3、6个月比较,观察组CARS评分明显低于对照组(P<0.05)。观察组总有效率为86.96%(40/46),对照组为65.22%(30/46),观察组优于对照组(P<0.05)。观察组不良反应发生率为2.17%(1/46),对照组为4.35%(2/46),2组比较差异无统计学意义(P>0.05)。结论针药结合治疗儿童孤独症疗效显著,可有效减轻患儿病情,改善其行为能力,安全性较好。
Objective To explore the efficacy of combination of acupuncture and medicine in children with autistim. Methods Totally 92 children with autism were randomly divided into observation group and control group according to the random table method, with 46 cases in each group. The control group received conventional rehabilitation therapy, while the observation group was treated with TCM syndrome differentiation treatment, one dosage per day, one times a day, orally. Observation group was also given acupuncture treatment, once a day, five times a week. Three months were one treatment course, and the treatment lasted for two courses. The clinical efficacy, Autism Behavior Checklist(ABC) score, Childhood Autism Rating Scale(CARS) score, and adverse reactions in the two groups were compared. Results Compared with before treatment, the scores of ABC in both groups were lower after 6 months of treatment(P<0.05); After 6 months of treatment, the self-care, communication, language, body movement, and sensory scores in the ABC scores of observation group were significantly lower than those in the control group(P<0.05). Compared with before treatment, the CARS scores of the two groups at 3 and 6 months were significantly lower(P<0.05); The CARS scores in the observation group were significantly lower than those in the control group at 3 and 6 months of treatment, with statistical significance(P<0.05). The total effective rate was 86.96%(40/46) in the observation group and 65.22%(30/46) in the control group. The observation group was better than the control group(P<0.05). The incidence of adverse reactions in the observation group was 2.17%(1/46), and that in the control group was 4.35%(2/46), without statistical significance(P>0.05). Conclusion For children with autism, acupuncture combined with medicine is with significant efficacy, which can effectively reduce their severity and improve their behavioral ability, with high safety.
Objective To explore the efficacy of combination of acupuncture and medicine in children with autistim. Methods Totally 92 children with autism were randomly divided into observation group and control group according to the random table method, with 46 cases in each group. The control group received conventional rehabilitation therapy, while the observation group was treated with TCM syndrome differentiation treatment, one dosage per day, one times a day, orally. Observation group was also given acupuncture treatment, once a day, five times a week. Three months were one treatment course, and the treatment lasted for two courses. The clinical efficacy, Autism Behavior Checklist(ABC) score, Childhood Autism Rating Scale(CARS) score, and adverse reactions in the two groups were compared. Results Compared with before treatment, the scores of ABC in both groups were lower after 6 months of treatment(P<0.05); After 6 months of treatment, the self-care, communication, language, body movement, and sensory scores in the ABC scores of observation group were significantly lower than those in the control group(P<0.05). Compared with before treatment, the CARS scores of the two groups at 3 and 6 months were significantly lower(P<0.05); The CARS scores in the observation group were significantly lower than those in the control group at 3 and 6 months of treatment, with statistical significance(P<0.05). The total effective rate was 86.96%(40/46) in the observation group and 65.22%(30/46) in the control group. The observation group was better than the control group(P<0.05). The incidence of adverse reactions in the observation group was 2.17%(1/46), and that in the control group was 4.35%(2/46), without statistical significance(P>0.05). Conclusion For children with autism, acupuncture combined with medicine is with significant efficacy, which can effectively reduce their severity and improve their behavioral ability, with high safety.
引文
[1]姚梅玲,王纪,李正华.儿童孤独症的综合干预治疗疗效分析[J].中国妇幼保健,2015,30(26):4463-4465.
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[3]刘超,卢斌,张瑜,等.机构结构化教育联合家庭康复训练治疗儿童孤独症的疗效观察[J].中国当代儿科杂志,2015,17(12):1277-1281.
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[5]钟霞,李维君,刘美华,等.2种儿童孤独症行为评定量表的临床应用比较[J].南昌大学学报(医学版),2012,52(7):81-83.
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[7]孙宇博,宋虎杰,冯涛珍,等.综合治疗童年孤独症60例临床分析[J].辽宁中医杂志,2016,43(10):2105-2108.
[8]李雪荣,陈劲梅.孤独症诊疗学[M].长沙:中南大学出版社,2004:56-78,97-98,160-195.
[9]周青蕊,景玉珍,王红梅,等.头针治疗与综合教育康复对儿童孤独症谱系障碍的疗效观察[J].中国儿童保健杂志,2015,23(3):332-335.
[10]樊亚妮,李建军,张武军.针药结合治疗孤独症心肝火旺型48例[J].吉林中医药,2017,37(4):400-403.
[11]王兴,庞芳,张玲,等.针刺联合中药改善孤独症谱系障碍患儿行为异常临床观察[J].陕西中医,2017,38(3):384-385.
[12]袁兆红,尤玉慧,姜秀芳,等.针刺治疗儿童孤独症临床研究的系统评价[J].环球中医药,2016,9(5):636-640.
[2]王莉,王锋.儿童孤独症早期干预效果及影响因素研究[J].精神医学杂志,2014,27(5):350-352.
[3]刘超,卢斌,张瑜,等.机构结构化教育联合家庭康复训练治疗儿童孤独症的疗效观察[J].中国当代儿科杂志,2015,17(12):1277-1281.
[4]美国精神病医学学会.精神障碍诊断与统计手册(第五版)[M].北京:北京大学出版社,2014:284-288.
[5]钟霞,李维君,刘美华,等.2种儿童孤独症行为评定量表的临床应用比较[J].南昌大学学报(医学版),2012,52(7):81-83.
[6]国家中医药管理局.中医病证诊断疗效标准[M].北京:中国医药科技出版社,2012:11.
[7]孙宇博,宋虎杰,冯涛珍,等.综合治疗童年孤独症60例临床分析[J].辽宁中医杂志,2016,43(10):2105-2108.
[8]李雪荣,陈劲梅.孤独症诊疗学[M].长沙:中南大学出版社,2004:56-78,97-98,160-195.
[9]周青蕊,景玉珍,王红梅,等.头针治疗与综合教育康复对儿童孤独症谱系障碍的疗效观察[J].中国儿童保健杂志,2015,23(3):332-335.
[10]樊亚妮,李建军,张武军.针药结合治疗孤独症心肝火旺型48例[J].吉林中医药,2017,37(4):400-403.
[11]王兴,庞芳,张玲,等.针刺联合中药改善孤独症谱系障碍患儿行为异常临床观察[J].陕西中医,2017,38(3):384-385.
[12]袁兆红,尤玉慧,姜秀芳,等.针刺治疗儿童孤独症临床研究的系统评价[J].环球中医药,2016,9(5):636-640.