维生素A、E水平与儿童反复呼吸道感染的相关性研究
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摘要
目的探讨维生素A、维生素E水平与儿童反复呼吸道感染的相关性。方法选取2016年1月～2018年1月在我院诊断的反复呼吸道感染儿童40例为研究组,另选择同期健康体检儿童40例为对照组,比较研究组和对照组的维生素A、维生素E水平及两组的维生素A、维生素E缺乏率。结果研究组患者的维生素A、维生素E检测水平显著少于对照组,差异具有显著性(P<0.05)。研究组的维生素A缺乏率为75.0%,显著高于对照组的20.0%,差异具有显著性(P<0.05)。研究组的维生素E缺乏率为2.5%,与对照组的维生素E缺乏率(5.0%)比较,差异无显著性(P>0.05)。结论儿童反复呼吸道感染的发生与机体维生素A和维生素E水平缺乏密切相关,补充维生素A、维生素E可作为防治儿童反复呼吸道感染的途径之一。
Objective To investigate the correlation between vitamin A, vitamin E levels and repeated respiratory infection in children. Methods 40 children with repeated respiratory infections diagnosed in our hospital from January 2016 to January 2018 were selected as the study group, and 40 healthy children in the same period were selected as the control group. The vitamin A, vitamin E, and vitamin A and vitamin E deficiency rates in the study group and the control group were compared. Results The levels of vitamin A and vitamin E in the study group were significantly lower than those in the control group, and the difference was significant(P<0.05). The vitamin A deficiency rate in the study group was 75.0%, which was significantly higher than that in the control group(20.0%), P<0.05. The study group's vitamin E deficiency rate was 2.5%, compared with the control group's vitamin E deficiency rate of 5.0%, the difference was not significant(P>0.05). Conclusion The occurrence of repeated respiratory infections in children is closely related to the lack of vitamin A and vitamin E levels in the body. Vitamin A and vitamin E supplementation can be used as one of the ways to prevent and treat children with repeated respiratory infections.
Objective To investigate the correlation between vitamin A, vitamin E levels and repeated respiratory infection in children. Methods 40 children with repeated respiratory infections diagnosed in our hospital from January 2016 to January 2018 were selected as the study group, and 40 healthy children in the same period were selected as the control group. The vitamin A, vitamin E, and vitamin A and vitamin E deficiency rates in the study group and the control group were compared. Results The levels of vitamin A and vitamin E in the study group were significantly lower than those in the control group, and the difference was significant(P<0.05). The vitamin A deficiency rate in the study group was 75.0%, which was significantly higher than that in the control group(20.0%), P<0.05. The study group's vitamin E deficiency rate was 2.5%, compared with the control group's vitamin E deficiency rate of 5.0%, the difference was not significant(P>0.05). Conclusion The occurrence of repeated respiratory infections in children is closely related to the lack of vitamin A and vitamin E levels in the body. Vitamin A and vitamin E supplementation can be used as one of the ways to prevent and treat children with repeated respiratory infections.
引文
[1]蒋璐,宋铁玎.维生素A辅助治疗小儿反复呼吸道感染的研究现状[J].中国中西医结合儿科学,2011,30(3):241-242.
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[12]李永强,赵婷,李贺晓,等.补充外源性维生素A、维生素E对反复呼吸道感染儿童的影响[J].中国妇幼保健,2018,33(16):3709-3710.
[13]Fan X,Liu S,Liu G,et al.Vitamin A deficiency impairs mucin expression and suppresses the mucosal immune function of the respiratory tract in chicks[J].PLoS One,2015,10(9):139.
[14]黄雪微,黄秀丽,翁薇洁.维生素A、E水平与反复儿童呼吸道感染的相关性研究[J].中国医药科学,2018,8(12):75-76.
[15]李文莉,刘春梅,管春梅,等.儿童维生素A、E水平与呼吸道感染疾病相关性研究[J].齐齐哈尔医学院学报,2016,37(22):2817-2818.
[16]乌绰然,查干娜,王莉,等,维生素A、E水平与儿童呼吸道感染相关性研究[J].医疗装备,2016,29(10):79-80.
[2]李秀云,黄从付,罗建军.反复呼吸道感染患儿血清维生素A和维生素E水平分析[J].中国医学工程,2017,25(12):19-20.
[3]盖琳琳.反复呼吸道感染患儿血清维生素A水平变化及其意义分析[J].中国现代药物应用,2016,10(13):47-48.
[4]张小君,李春融,卢君,等.维生素A治疗反复呼吸道感染的临床效果观察[J].中国民康医学,2015,31(9):63-64.
[5]唐迎元,谭爱斌,史文元.反复呼吸道感染、哮喘患儿血清维生素A水平的研究[J].实用临床医学,2015,16(1):72-74.
[6]Stenberg Hammar K,Hedlin G,Konradsen JR,et al.Subnormal levels of vitamin D are associated with acute wheeze in young children[J].Acta Paediatrica,2014,103(8):856-861.
[7]林凤姬.反复呼吸道感染患儿血清维生素A水平及其对免疫功能的影响分析[J].中国当代医药,2017,24(3):74-76.
[8]东利娟,仰曙芬.维生素A、E与反复呼吸道感染的研究进展[J].中国儿童保健杂志,2018,26(3):273-274.
[9]李亚,聂鑫,崔明明.儿童反复呼吸道感染与血清维生素A、D、E水平的相关性研究[J].中国儿童保健杂志,2017,25(6):634-636.
[10]Wu D,Meydani SN.Age-associated changes in immune function:impact of vitamins E intervention and the underlying mechanisms[J].Endocrine Metab Immune Disord Drug Targets,2014,14(4):283.
[11]何建业,王芳,高巍.维生素A/E水平与儿童呼吸道感染相关性研究[J].中国民康医学,2018,34(12):75-76.
[12]李永强,赵婷,李贺晓,等.补充外源性维生素A、维生素E对反复呼吸道感染儿童的影响[J].中国妇幼保健,2018,33(16):3709-3710.
[13]Fan X,Liu S,Liu G,et al.Vitamin A deficiency impairs mucin expression and suppresses the mucosal immune function of the respiratory tract in chicks[J].PLoS One,2015,10(9):139.
[14]黄雪微,黄秀丽,翁薇洁.维生素A、E水平与反复儿童呼吸道感染的相关性研究[J].中国医药科学,2018,8(12):75-76.
[15]李文莉,刘春梅,管春梅,等.儿童维生素A、E水平与呼吸道感染疾病相关性研究[J].齐齐哈尔医学院学报,2016,37(22):2817-2818.
[16]乌绰然,查干娜,王莉,等,维生素A、E水平与儿童呼吸道感染相关性研究[J].医疗装备,2016,29(10):79-80.