新生儿无创呼吸机防治新生儿呼吸窘迫综合征的效果及安全性观察
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摘要
目的分析无创呼吸机对新生儿呼吸窘迫综合征防治的效果和安全性。方法对本院2017年3月至2018年5月诊治新生儿呼吸窘迫综合征126例患儿临床资料加以分析,按照不同医治方案分成两组,将63例行机械通气医治患儿设为对照组,将63例行无创呼吸机医治患儿设为观察组,对两组效果、安全性进行比对、分析。结果观察组氧疗时间、用机时间和住院时间(70.35±22.10)h、(50.21±16.08)h和(13.20±7.06)d均比对照组短,且血氧饱和度、动脉血二氧化碳分压和动脉血氧分压(95.83±5.68)%、(30.41±3.20)mmHg和(88.68±8.51)mmHg均比对照组优(P<0.05);观察组总并发症率3.17%比对照组22.22%低(P<0.05)。结论无创呼吸机对新生儿呼吸窘迫综合征防治的效果佳,可缩短相关时间,改善患儿血气指标,且具较高安全性,值得临床应用与推广。
Objective To analyze the efficacy and safety of non-invasive ventilator in the prevention and treatment of neonatal respiratory distress syndrome. Methods In our hospital from March 2017 to May 2018, the diagnosis and treatment of neonatal respiratory distress syndrome clinical data analysis of 126 cases, divided into two groups according to different treatment scheme, the 63 routine mechanical ventilation treatment were set as control group, the 63 children of routine noninvasive ventilator to heal as observation group, to compare the effect of two groups, and analysis.Results The duration of oxygen therapy, machine use and hospital stay(70.35±22.10) h,(50.21±16.08) h and(13.20±7.06) d in the observation group were all shorter than those in the control group, and the blood oxygen saturation, arterial partial pressure of carbon dioxide and arterial partial pressure of oxygen(95.83±5.68)%,(30.41±3.20) mm Hg and(88.68±8.51) mmHg were all better than those in the control group(P<0.05). The total complication rate of the observation group was 3.17% lower than that of the control group(22.22%)(P<0.05). Conclusion Noninvasive ventilator has a good effect on the prevention and treatment of neonatal respiratory distress syndrome, can shorten the relevant time, improve the blood gas index of the children, and has a high safety, which is worthy of clinical application and promotion.
Objective To analyze the efficacy and safety of non-invasive ventilator in the prevention and treatment of neonatal respiratory distress syndrome. Methods In our hospital from March 2017 to May 2018, the diagnosis and treatment of neonatal respiratory distress syndrome clinical data analysis of 126 cases, divided into two groups according to different treatment scheme, the 63 routine mechanical ventilation treatment were set as control group, the 63 children of routine noninvasive ventilator to heal as observation group, to compare the effect of two groups, and analysis.Results The duration of oxygen therapy, machine use and hospital stay(70.35±22.10) h,(50.21±16.08) h and(13.20±7.06) d in the observation group were all shorter than those in the control group, and the blood oxygen saturation, arterial partial pressure of carbon dioxide and arterial partial pressure of oxygen(95.83±5.68)%,(30.41±3.20) mm Hg and(88.68±8.51) mmHg were all better than those in the control group(P<0.05). The total complication rate of the observation group was 3.17% lower than that of the control group(22.22%)(P<0.05). Conclusion Noninvasive ventilator has a good effect on the prevention and treatment of neonatal respiratory distress syndrome, can shorten the relevant time, improve the blood gas index of the children, and has a high safety, which is worthy of clinical application and promotion.
引文
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[11]田丽.无创呼吸机联合咖啡因治疗极低出生体重早产儿呼吸窘迫综合征的临床研究[J].中国医学创新,2017,14(3):63-66.
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[14]吴永强,赵景成,杨坤,等.无创呼吸机联合乌司他丁对急性呼吸窘迫综合征患者免疫及肝肾功能的影响[J].河北医药,2016,38(9):1327-1329.
[2]邝焯波.盐酸氨溴索治疗新生儿呼吸窘迫综合征的疗效分析[J].中国实用医药,2017,12(11):122-124.
[3]王乐.肺表面活性物质在新生儿呼吸窘迫综合征中的应用效果及对疾病指标的影响[J].中国妇幼保健,2017,32(12):2650-2652.
[4]文亚娜.不同给氧方式对新生儿呼吸窘迫综合征血气相关指标的改善作用及疗效观察[J].中外医学研究,2018,16(2):145-146.
[5]张维庭,温海峰.高频震荡通气在新生儿呼吸窘迫综合征中的应用效果评价[J].当代医学,2016,22(16):34-35.
[6]曾小靓,詹志义.无创呼吸机联合咖啡因治疗极低出生体质量早产儿呼吸窘迫综合征50例[J].当代医学,2018,24(4):140-141.
[7]张向阳.氨溴索联合CPAP呼吸机治疗新生儿呼吸窘迫综合征的临床研究[J].齐齐哈尔医学院学报,2017,38(9):1044-1045.
[8]孙静.固尔苏联合经鼻持续气道正压通气治疗新生儿呼吸窘迫综合征的疗效及其对血气指标的影响[J].黑龙江医药,2016,29(3):458-460.
[9]张瑞敏,刁玉巧,翟淑芬,等.3种无创辅助通气方式治疗新生儿呼吸窘迫综合征的临床研究[J].中国妇幼保健,2016,31(21):4441-4445.
[10]陈发明.无创呼吸机辅助通气治疗新生儿呼吸窘迫综合征的临床观察[J].中国处方药,2017,15(12):126-127.
[11]田丽.无创呼吸机联合咖啡因治疗极低出生体重早产儿呼吸窘迫综合征的临床研究[J].中国医学创新,2017,14(3):63-66.
[12]徐群,齐顺清,吴志兴.无创呼吸机对不同胎龄NRDS的临床应用研究[J].基层医学论坛,2017,21(32):4433-4435.
[13]郭颖.SIPAP双水平无创呼吸机治疗<35W早产儿NRDS疗效观察[J].航空航天医学杂志,2016,27(3):345-346.
[14]吴永强,赵景成,杨坤,等.无创呼吸机联合乌司他丁对急性呼吸窘迫综合征患者免疫及肝肾功能的影响[J].河北医药,2016,38(9):1327-1329.