复方樟柳碱注射液治疗糖尿病性视网膜病变的效果分析
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  • 英文篇名:Effect of Compound Anisodine Injection on Diabetic Retinopathy
  • 作者:高亚男 ; 杜楠 ; 陈玉春
  • 英文作者:GAO Ya-nan;DU Nan;CHEN Yu-chun;Department of Fundus Surgery, Liaocheng Guangming Eye Hospital;Department of Otolaryngology, Liaocheng Dongchangfu District Hospital;Department of Ophthalmology, Liaocheng Guangming Eye Hospital Hospetal;
  • 关键词:复方樟柳碱 ; 注射液 ; 糖尿病 ; 视网膜
  • 英文关键词:Compound anisodine;;Injection;;Diabetes;;Retina
  • 中文刊名:TNBX
  • 英文刊名:Diabetes New World
  • 机构:聊城市光明眼科医院眼底病内科;聊城市东昌府区中医院耳鼻喉科;聊城市光明眼科医院眼科;
  • 出版日期:2019-05-16
  • 出版单位:糖尿病新世界
  • 年:2019
  • 期:v.22
  • 语种:中文;
  • 页:TNBX201910098
  • 页数:2
  • CN:10
  • ISSN:11-5019/R
  • 分类号:196-197
摘要
目的分析复方樟柳碱注射液在治疗糖尿病性视网膜病变方面的临床疗效。方法该次研究的对象选择该院2017年1—12月收治的68例糖尿病性视网膜病变患者,并随机将其分为观察组和对照组,每组34例。所有患者均接受系统化眼科基础检查。对照组采用传统治疗方案,给予维生素C、维生素E与口服维脑路通的方式治疗,观察组则给予复方樟柳碱注射液的皮下注射方式,1次/d,一共15 d。治疗结束后比较两组患者的临床疗效。结果该次研究结果显示,在治疗有效率的数据对比方面,观察组治疗有效率达到了94.1%,但对照组的治疗有效率只有79.4%。结果表明观察组患者的眼底病变改善情况更好,且临床症状控制也优于对照组患者。两组患者治疗有效率数据差异有统计学意义(P<0.05)。结论复方樟柳碱注射液可以显著改善糖尿病性视网膜病变患者的血液供应情况,患者的视觉质量和预后恢复工作普遍较好,在糖尿病患者眼部并发症产生的早期或未出现明显视功能损害的时期进行病情控制,因此可以将其作为一种典型的治疗方案。
        Objective To analyze the clinical efficacy of compound anisodine injection in the treatment of diabetic retinopathy. Methods The subjects of this study were selected from 68 patients with diabetic retinopathy admitted to our hospital from January to December 2017. They were randomly divided into observation group and control group, with 34 cases in each group. All patients underwent a systematic ophthalmologic examination. The control group was treated with traditional treatment regimen, vitamin C, vitamin E and oral Weiluotong. The observation group was given subcutaneous injection of compound anisodine injection once a day, for 15 days. The clinical efficacy of the two groups was compared after the end of treatment. Results The results of this study showed that in the comparison of treatment effective data, the effective rate of the observation group was 94.1%, but the effective rate of the control group was only 79.4%. The results showed that the improvement of the fundus lesions in the observation group was better, and the clinical symptom control was better than the control group. There was significant difference in the treatment efficiency data between the two groups(P<0.05). Conclusion Compound anisodine injection can significantly improve the blood supply of patients with diabetic retinopathy. The visual quality and prognosis of patients are generally better. In the early stage of ocular complications of diabetic patients, there is no obvious visual impairment. The condition is controlled by the disease, so it can be used as a typical treatment.
引文
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    [2]吴育芝,黄峰.复方樟柳碱对糖尿病视网膜病变患者视神经与多焦视网膜电图的影响[J].实用药物与临床,2016,19(11):1393-1396.
    [3]孙世龙,张英杰,张颖.复方樟柳碱联合维生素B12对长期服用二甲双胍糖尿病视神经病变患者疗效观察[J].中国实用眼科杂志, 2016, 34(10):1090-1093.
    [4]何军.复方樟柳碱对糖尿病缺血性视神经病变疗效分析及对患者视力的影响[J].临床和实验医学杂志,2016,15(8):768-771.
    [5]利焕廉,周金文,左炜.复方樟柳碱联合降糖药物治疗糖尿病血管性假性视乳头炎的可行性及依从性研究[J].临床眼科杂志, 2015(3):224-226.
    [6]郭硕,王伟.疏血通注射液联合羟苯磺酸钙胶囊治疗单纯型糖尿病视网膜病变的疗效观察[J].现代药物与临床,2016,31(6):819-822.

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