孕妇生殖道B族链球菌感染与胎膜早破的关系及对母婴预后的影响
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摘要
目的:探讨孕妇生殖道B族链球菌(GBS)感染与胎膜早破的关系及对母婴预后结局的影响。方法:选取某院收治的胎膜早破孕妇85例作为观察对象,另选取同期正常妊娠的50例健康孕妇作为对照组。对所有孕妇的阴道拭子、肛拭子进行检测,分析GBS阳性与胎膜早破的关系及对母婴预后的影响。结果:观察组患者GBS感染阳性率明显高于对照组(21.18%vs 4.00%),P<0.05;观察组中GBS阳性患者发生产褥期感染、产后出血以及新生儿发生胎儿窘迫、新生儿肺炎的发生率明显高于GBS阴性患者,P<0.05。结论:孕妇生殖道B族链球菌感染可作为胎膜早破的高危因素,并且B族链球菌感染可能增加孕产妇产褥期感染、产后出血以及胎儿窘迫、新生儿感染等不良预后结局,临床应重视孕妇生殖道B族链球菌感染的检测、筛查以及治疗。
Objective:To investigate between B streptococcal infection in reproductive tract of pregnant women and premature rupture of fetal membranes and its effect on maternal and infant prognosis.Methods:85 pregnant women with premature rupture of membranes were selected as observation objects,and 50 healthy pregnant women with normal pregnancy at the same time were selected as control group.The vaginal swabs and anal swabs of all pregnant women were detected,and the relationship between GBS positive and premature rupture of membranes and the influence on the prognosis of mother and infant were analyzed.Results:The positive rate of GBS infection in the observation group was significantly higher than that in the control group(21.18% vs 4.00%)(P<0.05);In the observation group,the incidence of puerperal infection,postpartum hemorrhage and fetal distress in neonates of GBS positive patients was significantly higher than that of the GBS negative patients(P<0.05).Conclusion:B streptococcal infection in pregnant women may be a high risk factor for premature rupture of membranes,and B streptococcus infection may increase puerperal infection,postpartum hemorrhage and fetal distress,neonatal infection and other adverse outcomes.Clinical attention should be paid to the detection,screening and treatment of Group B streptococcus infection in pregnant women.
Objective:To investigate between B streptococcal infection in reproductive tract of pregnant women and premature rupture of fetal membranes and its effect on maternal and infant prognosis.Methods:85 pregnant women with premature rupture of membranes were selected as observation objects,and 50 healthy pregnant women with normal pregnancy at the same time were selected as control group.The vaginal swabs and anal swabs of all pregnant women were detected,and the relationship between GBS positive and premature rupture of membranes and the influence on the prognosis of mother and infant were analyzed.Results:The positive rate of GBS infection in the observation group was significantly higher than that in the control group(21.18% vs 4.00%)(P<0.05);In the observation group,the incidence of puerperal infection,postpartum hemorrhage and fetal distress in neonates of GBS positive patients was significantly higher than that of the GBS negative patients(P<0.05).Conclusion:B streptococcal infection in pregnant women may be a high risk factor for premature rupture of membranes,and B streptococcus infection may increase puerperal infection,postpartum hemorrhage and fetal distress,neonatal infection and other adverse outcomes.Clinical attention should be paid to the detection,screening and treatment of Group B streptococcus infection in pregnant women.
引文
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4 陈向利,李萌,黄超妹.妊娠晚期孕妇B族链球菌感染与胎膜早破的关联及对母婴预后的影响研究.北方药学,2016,13(6):91~92.
5 秦利,张利侠,袁军,等.孕妇生殖道B族链球菌感染与胎膜早破的关系及其对母儿预后的影响.国际检验医学杂志,2013,34(8):928~929.
2 彭凤梅,何春梅,古素芬.孕妇生殖道B族链球菌阳性与胎膜早破发生的关系.现代诊断与治疗,2015,26(2):277~278.
3 陈翠英.孕妇生殖道B族链球菌感染与胎膜早破的关系及对母婴预后的影响.深圳中西医结合杂志,2016,26(9):106~107.
4 陈向利,李萌,黄超妹.妊娠晚期孕妇B族链球菌感染与胎膜早破的关联及对母婴预后的影响研究.北方药学,2016,13(6):91~92.
5 秦利,张利侠,袁军,等.孕妇生殖道B族链球菌感染与胎膜早破的关系及其对母儿预后的影响.国际检验医学杂志,2013,34(8):928~929.