消痤胶囊提取工艺优选
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摘要
目的优选消痤胶囊水提物最佳提取工艺。方法采用L9(34)正交试验法进行试验,以加水量、煎煮时间、煎煮次数为因素,以绿原酸含量和干浸膏得率为指标,优选最佳提取工艺。结果消痤胶囊水提物最佳水提工艺为加8倍量水,提取2次,每次1 h。结论优选的最佳提取工艺方法简单,稳定性较好,可用于水提消痤胶囊。
Objective To optimize the extraction process of water extract of Xiaocuo Capsules. Methods L9( 34) orthogonal test was used to optimize the extraction process with the amount of water,decocting time and decocting times as factors,and with the content of chlorogenic acid and dry extract yield as indexes. Results The optimum water extraction process of Xiaocuo Capsules was as follows:adding 8 times of water,extracting twice with 1 h each time. Conclusion The optimum extraction process is simple and stable,which can be used for water extraction of Xiaocuo Capsules.
Objective To optimize the extraction process of water extract of Xiaocuo Capsules. Methods L9( 34) orthogonal test was used to optimize the extraction process with the amount of water,decocting time and decocting times as factors,and with the content of chlorogenic acid and dry extract yield as indexes. Results The optimum water extraction process of Xiaocuo Capsules was as follows:adding 8 times of water,extracting twice with 1 h each time. Conclusion The optimum extraction process is simple and stable,which can be used for water extraction of Xiaocuo Capsules.
引文
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[2]刘汉顺,张文家,庄明,等.枇杷清肺饮加减联合加味颠倒散治疗痤疮的临床观察[J].安徽医药,2012,16(1):108-109.
[3]郑建本,王光富.加味犀角地黄汤治疗痤疮80例[J].实用中医药杂志,2004,20(1):18-19.
[4]郑永刚.重用金银花治疗轻中度痤疮[J].吉林中医药,2013,33(8):798-799.
[5]韩冬,赵洪峰,解生旭.正交试验探讨金银花中绿原酸最佳提取条件[J].中国社区医师:综合版,2006,8(23):20.
[6]丁青龙,赵静安.用正交试验探讨金银花煎煮条件对绿原酸含量的影响[J].中国新药杂志,1999,8(10):33-35.
[7]余杰,匡辽国,林凡胜.正交试验研究金银花的水提工艺[J].现代药物与临床,2010,25(4):293-296.
[8]白翠兰,李昭日格图,萨仁格日乐,等.消食十味丸的质量标准[J].中成药,2015,37(9):1951-1955.
[9]陶春,薛丹平,黄爱文,等.兰翘解毒口服液的质量标准的提高[J].中国药师,2016,19(9):1763-1766.
[10]杨方.小儿感冒颗粒的质量标准研究[J].世界中医药,2015,10(3):427-430.
[11]王志萍,黎芳,陈勇,等.壮药妇雅净颗粒质量标准研究[J].中成药,2013,35(11):2422-2426.