Fine-tuning the response of growth cones to guidance cues: a perspective on the role of microRNAs
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摘要
<正>In the development and regeneration of the nervous system,neurons face the complex task of establishing and/or repairing neuronal connections and contacts.The formation of these neuronal circuits is largely coordinated by tightly regulated temporal and spatial changes in mRNA translation,which enables incredibly precise control over protein expression and localization(Jung and Holt,2011).Local mRNA
引文
Baudet ML,Zivraj KH,Abreu-Goodger C,Muldal A,Armisen J,Blenkiron C,Goldstein LD,Miska EA,Holt CE(2011)Nat Neurosci 15:29-38.
Bellon A,Iyer A,Bridi S,Lee FCY,Ovando-Vazquez C,Corradi E,Longhi S,Roccuzzo M,Strohbuecker S,Naik S,Sarkies P,Miska E,Abreu-Goodger C,Holt CE,Baudet ML(2017)miR-182 regulates Slit2-mediated axon guidance by modulating the local translation of a specific mRNA.Cell Rep18:1171-1186.
Bhalala OG,Srikanth M,Kessler JA(2013)The emerging roles of microRNAs in CNS injuries.Nat Rev Neurol 9:328-339.
Dajas-Bailador F,Bonev B,Garcez P,Stanley P,Guillemot F,Papalopulu N(2012)microRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons.Nat Neurosci 15:697-699.
Han L,Wen Z,Lynn RC,Baudet ML,Holt CE,Sasaki Y,Bassell GJ,Zheng JQ(2011)Regulation of chemotropic guidance of nerve growth cones by microRNA.Mol Brain 4:40.
Hancock ML,Preitner N,Quan J,Flanagan JG(2014)MicroRNA-132 is enriched in developing axons locally regulates Rasa1 mRNA,and promotes axon extension.J Neurosci 34:66-78.
Jung H,Holt CE(2011)Local translation of mRNAs in neural development.Wiley Interdiscip Rev RNA 2:153-165.
Marler KJ,Suetterlin P,Dopplapudi A,Rubikaite A,Adnan J,Maiorano NA,Lowe AS,Thompson ID,Pathania M,Bordey A,Fulga T,Van Vactor DL,Hindges R,Drescher U(2014)BDNF promotes axon branching of retinal ganglion cells via miRNA-132 and p250GAP.J Neurosci 34:969-979.
Stoeckli ET(2018)Understanding axon guidance:Are we nearly there yet?Development doi:10.1242/dev.151415.
Walker SE,Necakov A,Spencer GE,Carlone RL(2018)Identification and characterization of microRNAs during retinoic-acid induced regeneration of a molluscan central nervous system.Int J Mol Sci doi:10.3390/ijms19092741.
Wang B,Pan L,Wei M,Wang Q,Liu WW,Wang N,Jiang XY,Zhang X,Bao L(2015)FMRP-mediated axonal delivery of miR-181d regulates axon elongation by locally targeting Map1b and Calm1.Cell Rep 13:2794-2807.
Zou Y,Chiu H,Domenger D,Chuang CF,Chang C(2012)The lin-4 microR-NA targets the LIN-14 transcription factor to inhibit netrin-mediated axon attraction.Sci Signal 5:228.
Bellon A,Iyer A,Bridi S,Lee FCY,Ovando-Vazquez C,Corradi E,Longhi S,Roccuzzo M,Strohbuecker S,Naik S,Sarkies P,Miska E,Abreu-Goodger C,Holt CE,Baudet ML(2017)miR-182 regulates Slit2-mediated axon guidance by modulating the local translation of a specific mRNA.Cell Rep18:1171-1186.
Bhalala OG,Srikanth M,Kessler JA(2013)The emerging roles of microRNAs in CNS injuries.Nat Rev Neurol 9:328-339.
Dajas-Bailador F,Bonev B,Garcez P,Stanley P,Guillemot F,Papalopulu N(2012)microRNA-9 regulates axon extension and branching by targeting Map1b in mouse cortical neurons.Nat Neurosci 15:697-699.
Han L,Wen Z,Lynn RC,Baudet ML,Holt CE,Sasaki Y,Bassell GJ,Zheng JQ(2011)Regulation of chemotropic guidance of nerve growth cones by microRNA.Mol Brain 4:40.
Hancock ML,Preitner N,Quan J,Flanagan JG(2014)MicroRNA-132 is enriched in developing axons locally regulates Rasa1 mRNA,and promotes axon extension.J Neurosci 34:66-78.
Jung H,Holt CE(2011)Local translation of mRNAs in neural development.Wiley Interdiscip Rev RNA 2:153-165.
Marler KJ,Suetterlin P,Dopplapudi A,Rubikaite A,Adnan J,Maiorano NA,Lowe AS,Thompson ID,Pathania M,Bordey A,Fulga T,Van Vactor DL,Hindges R,Drescher U(2014)BDNF promotes axon branching of retinal ganglion cells via miRNA-132 and p250GAP.J Neurosci 34:969-979.
Stoeckli ET(2018)Understanding axon guidance:Are we nearly there yet?Development doi:10.1242/dev.151415.
Walker SE,Necakov A,Spencer GE,Carlone RL(2018)Identification and characterization of microRNAs during retinoic-acid induced regeneration of a molluscan central nervous system.Int J Mol Sci doi:10.3390/ijms19092741.
Wang B,Pan L,Wei M,Wang Q,Liu WW,Wang N,Jiang XY,Zhang X,Bao L(2015)FMRP-mediated axonal delivery of miR-181d regulates axon elongation by locally targeting Map1b and Calm1.Cell Rep 13:2794-2807.
Zou Y,Chiu H,Domenger D,Chuang CF,Chang C(2012)The lin-4 microR-NA targets the LIN-14 transcription factor to inhibit netrin-mediated axon attraction.Sci Signal 5:228.