肾癌基础和临床研究的所思所悟
摘要
<正>肾癌是泌尿生殖系统最常见的恶性肿瘤之一,约占成人全身恶性肿瘤的3%。近年来,全世界肾癌的发病率和病死率以每10年2%～3%的速度增加,呈现上升趋势。在中国,肾癌的发病率在过去的20年间以平均每年6.5%的速度增长,在泌尿系统肿瘤相关死亡中位居第一位。其中,在被诊断为肾癌的患者中,有20%～30%属于晚期。肾癌对人民群众生命健康的危害越来越大。因此,研究探索肾癌预防、诊断以及治疗的有效方法已刻不容缓。"情独于肾,与肾为伴",我从事泌尿外科肾脏专科专病工作近30余
引文
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[3]ZHAI W,SUN Y,JIANG M,et al.Differential regulation of LncRNA-SARCC suppresses VHL-mutant RCC cell proliferation yet promotes VHL-normal RCC cell proliferation via modulating androgen receptor/HIF-2α/C-MYC axis under hypoxia[J].Oncogene,2016,35(37):4866-4880.
[4]YANG B,GU W,PENG B,et al.High level of circulating endothelial progenitor cells positively correlates with serum vascular endothelial growth factor in patients with renal cell carcinoma[J].J Urol,2012,188(6):2055-2061.