作者：Nizar S. Abdelfattah ; MD¹ ; ² ; ^{nizar@ucla.edu} ; Mayss Al-Sheikh ; MD¹ ; ² ; Sean Pitetta ; BS¹ ; Ahmed Mousa ; PhD³ ; SriniVas R. Sadda ; MD¹ ; ² ; Charles C. Wykoff ; MD ; PhD⁴ ; ⁵ ; on behalf of the Treat-and-Extend Age-Related Macular Degeneration Study Group^&lowast ; ; Charles C. Wykoff ; MD ; PhD ; Daniel E. Croft ; BA ; David M. Brown ; MD ; Rui Wang ; BA ; John F. Payne ; MD ; Lloyd Clark ; MD ; Nizar Saleh Abdelfattah ; MD ; SriniVas R. Sadda ; MD ; Matthew S. Benz ; MD ; Eric Chen ; MD ; Richard H. Fish ; MD ; David L. Johnson ; MD ; Rosa Y. Kim ; MD ; James C. Major Jr. ; MD ; Ronan E. O'Malley ; MD ; Amy C. Schefler ; MD ; Ankoor R. Shah ; MD ; Sushma K. Vance ; MD ; John A. Wells III ; MD ; Tien P. Wong ; MD

关键词：AMD ; age-related macular degeneration ; CATT ; Comparison of AMD Treatments Trials ; CNV ; choroidal neovascularization ; ERMA ; enlargement rate of macular atrophy ; FAF ; fundus autofluorescence ; FCT ; foveal choroidal thickness ; GA ; geographic atrophy ; MA ; macular atrophy ; PED ; pigment epithelial detachment ; RPE ; retinal pigment epithelium ; SHRM ; subretinal hyperreflective material ; SRF ; subretinal fluid ; TREX ; treat-and-extend ; TREX-AMD ; Treat-and-Extend Age-Related Macular Degeneration ; VEGF ; vascul

刊名：Ophthalmology

出版年：2017

作者：Fang Ko ; MD¹ ; Paul J. Foster ; PhD ; FRCOphth¹ ; Nicholas G. Strouthidis ; PhD ; FRCOphth¹ ; Yusrah Shweikh ; MBChB ; MRes¹ ; Qi Yang ; PhD² ; Charles A. Reisman ; MS² ; Zaynah A. Muthy ; BSc¹ ; Usha Chakravarthy ; MD ; PhD³ ; Andrew J. Lotery ; MD ; FRCOphth⁴ ; Pearse A. Keane ; MD ; MRCOphth¹ ; Adnan Tufail ; MD ; FRCOphth¹ ; Carlota M. Grossi ; PhD¹ ; Praveen J. Patel ; MD ; FRCOphth¹ ; ^{praveen.patel@moorfields.nhs.uk} ; on behalf of the UK Biobank Eye & Vision Consortium^&lowast ;

关键词：BM ; Bruch's membrane ; BMI ; body mass index ; BP ; blood pressure ; CI ; confidence interval ; D ; diopter ; ETDRS ; Early Treatment of Diabetic Retinopathy Study ; ILM ; internal limiting membrane ; IOP ; intraocular pressure ; NFL ; nerve fiber layer ; OCT ; optical coherence tomography ; RPE ; retinal pigment epithelium ; SD ; standard deviation ; SE ; standard error ; TABS ; Topcon Advanced Boundary Segmentation

刊名：Ophthalmology

出版年：2017

作者：Qiang Zhou ; MD¹ ; Ebenezer Daniel ; MBBS ; PhD² ; Maureen G. Maguire ; PhD² ; Juan E. Grunwald ; MD² ; E. Revell Martin ; BA² ; Daniel F. Martin ; MD³ ; Gui-shuang Ying ; PhD² ; ^{gsying@mail.med.upenn.edu" class="auth_mail" title="E-mail the corresponding author} ; on behalf of the Comparison of Age-Related Macular Degeneration Treatments Trials Research Group^&lowast ;

关键词：AMD ; age-related macular degeneration ; AREDS ; Age-Related Eye Diseases Study ; aRR ; adjusted risk ratio ; CATT ; Comparison of Age-Related Macular Degeneration Treatments Trials ; CFP ; color fundus photography ; CI ; confidence interval ; FA ; fluorescein angiography ; GA ; geographic atrophy ; nAMD ; neovascular age-related macular degeneration ; OCT ; optical coherence tomography ; PRN ; pro re nata ; RF ; red-free ; RPE ; retinal pigment epithelium ; RR ; risk ratio ; SD ; spectral-domain

刊名：Ophthalmology

出版年：2016

作者：Gui-shuang Ying ; PhD¹ ; ^{gsying@mail.med.upenn.edu" class="auth_mail" title="E-mail the corresponding author} ; Maureen G. Maguire ; PhD¹ ; Ebenezer Daniel ; PhD¹ ; Juan E. Grunwald ; MD¹ ; Osama Ahmed² ; Daniel F. Martin ; MD³ ; on behalf of the Comparison of Age-Related Macular Degeneration Treatments Trials Research Group^&lowast ;

关键词：AMD ; age-related macular degeneration ; CATT ; Comparison of Age-Related Macular Degeneration Treatments Trials ; CI ; confidence interval ; CNV ; choroidal neovascularization ; CVD ; cardiovascular disease ; DA ; disc area ; OR ; odds ratio ; PRN ; pro re nata

刊名：Ophthalmology

出版年：2016

作者：Robert L. Johnston ; FRCOphth¹ ; ^&lowast ; ; Aaron Y. Lee ; MD ; MSCI² ; ³ ; ^&lowast ; ; ^{leeay@uw.edu" class="auth_mail" title="E-mail the corresponding author} ; Miranda Buckle ; MB BChir⁵ ; Richard Antcliff ; MD ; FRCOphth⁴ ; Clare Bailey ; MD ; FRCOphth⁵ ; Martin McKibbin ; FRCOphth⁶ ; Usha Chakravarthy ; MD ; PhD⁷ ; Adnan Tufail ; MD ; FRCOphth³ ; on behalf of the UK AMD EMR Users Group

关键词：AMD ; age-related macular degeneration ; ANCHOR ; Anti&ndash ; Vascular Endothelial Growth Factor Antibody for the Treatment of Predominantly Classic Choroidal Neovascularization in Age-Related Macular Degeneration ; anti-VEGF ; inhibitor of vascular endothelial growth factor ; EMR ; electronic medical record system ; ETDRS ; Early Treatment Diabetic Retinopathy Study ; MARINA ; Minimally Classic/Occult Trial of the Anti-VEGF Antibody Ranibizumab in the Treatment of Neovascular Age-Related Macular Degenerati

刊名：Ophthalmology

出版年：2016

作者：Timothy L. Jackson ; PhD ; FRCOphth¹ ; ² ; ^{t.jackson1@nhs.net" class="auth_mail" title="E-mail the corresponding author} ; Riti Desai ; MPhil ; MSc² ; Andrew Simpson ; MBBS ; FRCOphth¹ ; ² ; James E. Neffendorf ; MA ; MBBS¹ ; ² ; Robert Petrarca ; MD (Res) ; FRCOphth¹ ; ² ; Kelly Smith ; MS³ ; Janet Wittes ; PhD³ ; Cornelius Lewis ; PhD¹ ; ⁴ ; Luke Membrey ; MD ; FRCOphth⁵ ; Richard Haynes ; MD ; FRCOphth⁶ ; Mark Costen ; FRCOphth⁷ ; David H.W. Steel ; FRCOphth⁸ ; Alyson Muldrew ; PhD⁹ ; Usha Chakravarthy ; PhD ; FRCOphth⁹ ; on behalf of the Macular Epiretinal Brachytherapy versus Ranibizumab (Lucentis) Only Treatment (MERLOT) Study Group^&lowast ;

关键词：AMD ; age-related macular degeneration ; BCVA ; best-corrected visual acuity ; CABERNET ; Choroidal Neovascularization Secondary to Age-Related Macular Degeneration Treated with Beta Radiation Epiretinal Therapy ; CNV ; choroidal neovascularization ; EMB ; epimacular brachytherapy ; ETDRS ; Early Treatment of Diabetic Retinopathy Study ; INTREPID ; IRay in Conjunction with Anti-VEGF Treatment for Patients with Wet AMD ; MERITAGE ; Macular Epiretinal Brachytherapy in Treated Age-Related Macular Degeneration ; ME

刊名：Ophthalmology

出版年：2016

作者：Yumiko Akagi-Kurashige ; MD¹ ; ² ; Kenji Yamashiro ; MD ; PhD¹ ; ^{yamashro@kuhp.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Norimoto Gotoh ; MD ; PhD¹ ; ² ; Masahiro Miyake ; MD¹ ; ² ; Satoshi Morooka ; MD¹ ; Munemitsu Yoshikawa ; MD¹ ; ² ; Isao Nakata ; MD ; PhD¹ ; ² ; Kyoko Kumagai ; MD ; PhD¹ ; Akitaka Tsujikawa ; MD ; PhD¹ ; Ryo Yamada ; MD ; PhD² ; Fumihiko Matsuda ; PhD² ; Masaaki Saito ; MD ; PhD³ ; Tomohiro Iida ; MD ; PhD⁴ ; Masako Sugahara ; MD⁵ ; Yasuo Kurimoto ; MD ; PhD⁵ ; Ching-Yu Cheng ; MD ; PhD⁶ ; ⁷ ; ⁸ ; ⁹ ; Chiea-Chuen Khor ; MBBS ; PhD⁶ ; ¹⁰ ; ¹¹ ; Tien-Yin Wong ; FRCS ; PhD⁶ ; ⁷ ; ⁸ ; ⁹ ; Nagahisa Yoshimura ; MD ; PhD¹ ; on behalf of the Nagahama Cohort Research Group^&lowast ; ; Takeo Nakayama ; Akihiro Sekine ; Shinji Kosugi ; Takahisa Kawaguchi ; Ryo Yamada ; Yasuharu Tabara ; Fumihiko Matsuda

关键词：AMD ; age-related macular degeneration ; cDNA ; complementary DNA ; CNV ; choroidal neovascularization ; GLD ; greatest linear dimension ; GWAS ; genome-wide association study ; LD ; linkage disequilibrium ; MMP ; matrix metalloprotease ; PCV ; polypoidal choroidal vasculopathy ; RPE ; retinal pigment epithelium ; SNP ; single nucleotide polymorphism ; tAMD ; typical age-related macular degeneration ; VEGF ; vascular endothelial growth factor

刊名：Ophthalmology

出版年：2015

作者：Charles C. Wykoff ; MD ; PhD¹ ; ² ; ^{ccwmd@houstonretina.com" class="auth_mail" title="E-mail the corresponding author} ; Daniel E. Croft ; BA¹ ; David M. Brown ; MD¹ ; ² ; Rui Wang ; BA¹ ; John F. Payne ; MD³ ; Lloyd Clark ; MD³ ; Nizar Saleh Abdelfattah ; MD⁴ ; ⁵ ; SriniVas R. Sadda ; MD⁴ ; ⁵ ; on behalf of the TREX-AMD Study Group^&lowast ;

关键词：AMD ; age-related macular degeneration ; BCVA ; best-corrected visual acuity ; CRT ; central retinal thickness ; ETDRS ; Early Treatment Diabetic Retinopathy Study ; OCT ; optical coherence tomography ; PRN ; pro re nata ; SD ; spectral-domain ; TREX ; treat-and-extend ; VA ; visual acuity ; VEGF ; vascular endothelial growth factor

刊名：Ophthalmology

出版年：2015

作者：Gui-shuang Ying ; PhD¹ ; ^{gsying@mail.med.upenn.edu" class="auth_mail" title="E-mail the corresponding author} ; Maureen G. Maguire ; PhD¹ ; Ebenezer Daniel ; MBBS ; PhD¹ ; Frederick L. Ferris ; MD² ; Glenn J. Jaffe ; MD³ ; Juan E. Grunwald ; MD¹ ; Cynthia A. Toth ; MD³ ; Jiayan Huang ; MS¹ ; Daniel F. Martin ; MD⁴ ; on behalf of the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT) Research Group^&lowast ;

关键词：AMD ; age-related macular degeneration ; CATT ; Comparison of Age-Related Macular Degeneration Treatments Trials ; CNV ; choroidal neovascularization ; OCT ; optical coherence tomography ; PRN ; pro re nata ; RPE ; retinal pigment epithelium ; VA ; visual acuity ; VEGF ; vascular endothelial growth factor

刊名：Ophthalmology

出版年：2015