搜索页_ AMP- activated protein kinase α

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1.13-Ethylberberine reduces HMGB1 release through AMPK activation in LPS-activated RAW264.7 cells and protects endotoxemic mice from organ damage

作者：Dong Ung Lee^c ; ¹ ; Young Shin Ko^a ; ¹ ; Hye Jung Kim^a ; ^b ; Ki Churl Chang^a ; ^b ; ^{kcchang@gnu.kr}

关键词：BBR ; berberine ; CLP ; cecal ligation and puncture ; HMGB1 ; high mobility group box 1 ; HO-1 ; heme oxygenase-1 ; iNOS ; inducible nitric oxide synthase ; LPS ; lipopolysaccharide ; NF-κB ; Nuclear factor kappa B ; NO ; nitric oxide ; siRNA ; small interfering RNA ; H&E ; hematoxylin and eosin ; PCNA ; proliferating cell nuclear antigen ; DMEM ; dulbecco&rsquo ; s modified eagle&rsquo ; s medium ; FBS ; fatal bovine serum ; AMPK ; AMP-activated protein kinase ; 13-EBR ; 13-ethylberberine ; TNF-α ; tumor necrosis factor-alpha ; I

刊名：Biomedicine & Pharmacotherapy

出版年：2017

2.Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation

作者：Sarah J. Mancini^a ; Anna D. White^a ; Silvia Bijland^a ; ¹ ; Claire Rutherford^a ; Delyth Graham^a ; Erik A. Richter^b ; Benoit Viollet^c ; ^d ; ^e ; Rhian M. Touyz^a ; Timothy M. Palmer^f ; Ian P. Salt^a ; ^{Ian.Salt@glasgow.ac.uk}

关键词：Adipocyte ; AMP-activated protein kinase ; Inflammation ; Signalling

刊名：Molecular and Cellular Endocrinology

出版年：2017

3.Globular CTRP3 promotes mitochondrial biogenesis in cardiomyocytes through AMPK/PGC-1α pathway

作者：Cheng-Lin Zhang^a ; ^c ; ^d ; Han Feng^a ; ^c ; ^d ; Li Li^a ; ^c ; ^d ; Jin-Yu Wang^a ; ^c ; ^d ; Dan Wu^a ; ^c ; ^d ; Yan-Ting Hao^b ; Zheng Wang^b ; Yan Zhang^a ; ^c ; ^d ; ^{zhangy18@bjmu.edu.cn} ; Li-Ling Wu^a ; ^c ; ^d ; ^{pathophy@bjmu.edu.cn}

关键词：AMPK ; AMP-activated protein kinase ; AraA ; adenine 9-β-d-arabinofuranoside ; ATP-5β ; ATP synthase 5β ; Cyt B ; cytochrome B ; CTRP3 ; C1q/tumor necrosis factor-related protein-3 ; FCCP ; carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone ; H/R ; hypoxia-reoxygenation ; Mfn-2 ; mitofusin 2 ; mtDNA ; mitochondrial DNA ; NAD+ ; ; nicotinamide adenine dinucleotide ; NRF-1 ; nuclear respiratory factor 1 ; NRVMs ; neonatal rat ventricular myocytes ; OCR ; oxygen consumption rate ; OXPHOS ; oxidative phosphorylation ; P

刊名：Biochimica et Biophysica Acta (BBA) - General Subjects

出版年：2017

4.Acute fluoride poisoning alters myocardial cytoskeletal and AMPK signaling proteins in rats

作者：Lakshmikanthan Panneerselvam ; Azhwar Raghunath ; Ekambaram Perumal ; ^{ekas2009@buc.edu.in}

关键词：ACC ; Acetyl coA carboxylase ; AMPK ; 5&prime ; adenosine monophosphate-activated protein kinase ; ATP ; Adenosine Triphosphate ; IF ; Intermediate filaments ; DAB ; 3 ; 3&prime ; -Diaminobenzidine ; TMB ; 3 ; 3&prime5 ; 5&prime ; -Tetramethylbenzidine

刊名：International Journal of Cardiology

出版年：2017

5.The inhibition of spinal synaptic plasticity mediated by activation of AMP-activated protein kinase signaling alleviates the acute pain induced by oxaliplatin

作者：Yun-Zhi Ling^a ; ¹ ; Zhen-Yu Li^b ; ¹ ; Han-Dong Ou-Yang^c ; ¹ ; Chao Ma^d ; Shao-Ling Wu^d ; Jia-You Wei^a ; Huan-Huan Ding^a ; Xiao-Long Zhang^a ; Meng Liu^a ; Cui-Cui Liu^d ; ^{lucyliucuicui@126.com} ; Zhen-Zhen Huang^a ; ^{Huangzhzh3@mail.sysu.edu.cn} ; Wen-Jun Xin^a

关键词：AMPKα ; LTP ; mTOR/p70S6K signal pathway ; Oxaliplatin ; Acute pain

刊名：Experimental Neurology

出版年：2017

6.Down-regulation of fibroblast growth factor 2 and its co-receptors heparan sulfate proteoglycans by resveratrol underlies the improvement of cardiac dysfunction in experimental diabetes

作者：Cé ; lia Maria Cá ; ssaro Strunz ; ^{labcelia@incor.usp.br} ; Alessandra Roggerio ^{alessandra.roggerio@incor.usp.br} ; Paula Lá ; zara Cruz ^{paulalcruz@gmail.com} ; Ana Paula Pacanaro ^{ana.pacanaro@incor.usp.br} ; Vera Maria Cury Salemi ^{verasalemi@uol.com.br} ; Luiz Alberto Benvenuti ^{benvenutianpluiz@incor.usp.br} ; Antonio de Pá ; dua Mansur ^{antonio.mansur@incor.usp.br} ; Maria Clá ; udia Irigoyen ^{maria.irigoyen@incor.usp.br}

关键词：A ; Late diastolic mitral inflow ; A&rsquo ; late diastolic peak velocity ; AMPK ; AMP-activated protein kinase ; BMI ; Body mass index ; E ; Early diastolic mitral inflow ; E&rsquo ; early diastolic peak velocity ; FGF ; Fibroblast Growth Factor ; GAPDH ; Glyceraldehyde 3-phosphate dehydrogenase ; HSPGs ; Heparan sulfate proteoglycans ; IVRT ; Isovolumic relaxation time ; LV ; Left ventricular ; N-A ; Naso-anal length ; PPARα ; Peroxisome proliferator-activated receptor alpha ; PPARγ ; Peroxisome proliferator-activated

刊名：The Journal of Nutritional Biochemistry

出版年：2017

7.Reggie-1 and reggie-2 (flotillins) participate in Rab11a-dependent cargo trafficking, spine synapse formation and LTP-related AMPA receptor (GluA1) surface exposure in mouse hippocampal neurons

作者：Vsevolod Bodrikov^a ; ^{Vsevolod.Bodrikov@uni-konstanz.de} ; Aline Pauschert^a ; ^{AlinePauschert@web.de} ; Gaga Kochlamazashvili^b ; ^{kochlamazashvili@fmp-berlin.de} ; Claudia A.O. Stuermer^a ; ^{Claudia.Stuermer@uni-konstanz.de}

关键词：CA ; constitutive active ; ECS ; extracellular solution ; EGFP ; enhanced green fluorescent protein ; EHD ; Eps15 homology domain-containing proteins ; Flot2 ; flotillin-2 ; k.o. ; knock out ; LTP ; long term potentiation ; MAPK ; mitogen-activated kinase ; div ; days in culture ; GluN1 ; NMDA receptor subunit 1 (NMDA receptor ; N-Methyl-d-Aspartate receptor) ; GluA1 ; glutamate receptor subunit 1 (AMPA receptor ; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor) ; RFP ; red fluorescent protein ; FM4-64FX ; f

刊名：Experimental Neurology

出版年：2017

8.Identification of novel peptide motifs in the serpin maspin that affect vascular smooth muscle cell function

作者：S.E. Jenkinson^a ; ^b ; L.J. Brown^a ; J. Ombor^a ; J.A. Milburn^a ; T. Smulders-Srinivasan^a ; S. Veuger^a ; D.R. Edwards^c ; R. Bass^a ; ^{r.bass@uea.ac.uk}

关键词：VSMC ; vascular smooth muscle cells ; S4B ; strand 4 of beta sheet B ; S5B ; strand 5 of beta sheet B ; RCL ; reactive centre loop ; AMPK ; AMP-activated protein kinase ; G-helix ; G α-helix ; S1A ; strand 1 of beta sheet A ; S2C ; strand 2 of beta sheet C

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

出版年：2017

9.Hederagenin and α-hederin promote degradation of proteins in neurodegenerative diseases and improve motor deficits in MPTP-mice

作者：An-Guo Wu^a ; ¹ ; Wu Zeng^a ; ¹ ; Vincent Kam-Wai Wong^a ; Yi-Zhun Zhu^b ; Amy C.Y. Lo^c ; Liang Liu^a ; ^{lliu@must.edu.mo} ; Betty Yuen-Kwan Law^a ; ^{yklaw@must.edu.mo}

关键词：CHMs ; Chinese herbal medicines ; ATG ; autophagy-related proteins ; AD ; Alzheimer&rsquo ; s disease ; PD ; Parkinson&rsquo ; s disease ; AMPK ; 5&prime ; adenosine monophosphate-activated protein kinase ; mTOR ; mammalian target of rapamycin ; HD ; Huntington&rsquo ; s disease ; HH ; hedera helix ; PF ; petroleum ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; EF ; ethylacetate fraction ; HTT ; huntingtin ; NF ; n-butanol ; GFP ; green fluorescent protein ; PE ; phosphatidylethanolamine ; AHS ; acid hydrolyzed solution ; CM

刊名：Pharmacological Research

出版年：2017

10.The neurological effects of ghrelin in brain diseases: Beyond metabolic functions

作者：Qian Jiao^a ; ^b ; ¹ ; ^{jiaoqian2006@126.com} ; Xixun Du^a ; ^b ; ¹ ; ^{xunxundu@163.com} ; Yong Li^a ; ^b ; ^{liyong_55@sina.cn} ; Bing Gong^a ; ^{gongxian666@163.com} ; Limin Shi^a ; ^b ; ^{slm0532@163.com} ; Tingting Tang^a ; ^b ; ^{sunnyting1230@126.com} ; Hong Jiang^a ; ^b ; ^{hongjiang@qdu.edu.cn}

关键词：ACCα ; acetyl-CoA carboxylase α ; AD ; Alzheimer&rsquo ; s disease ; ALS ; amyotrophic lateral sclerosis ; AMPARs ; α-amino-3-hydroxy-5- methyl-4-isoxazole propionic-type receptors ; AgRP ; agouti-related protein ; AMPK ; adenosine monophosphate-activated protein kinase ; ARH ; arcuate nucleus of hypothalamus ; ATF ; activating transcription factor ; BBB ; blood&ndash ; brain barrier ; CaMKII ; Ca2+/calmodulin dependent protein kinase II ; CART ; cocaine and amphetamine regulated transcriptpeptide ; DG ; dentate gyrus ; DM

刊名：Neuroscience & Biobehavioral Reviews

出版年：2017

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