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1.Cross-sectional and longitudinal associations of motor fluctuations and non-motor predominance with cerebrospinal τ and Aβ as well as dementia-risk in Parkinson's disease

作者：Raluca Modreanu^a ; ^b ; Sonia Catalina Cerquera^a ; ^c ; Marí ; a José ; Martí ; ^a ; José ; Rí ; os^d ; Almudena Sá ; nchez-Gó ; mez^a ; Ana Cá ; mara^a ; Manel Ferná ; ndez^a ; Yaroslau Compta^a ; ^{ycompta@clinic.cat}

关键词：Parkinson's disease-dementia ; CSF Aβ ; CSF τ ; Endophenotypes ; Non-motor symptoms ; Motor fluctuations

刊名：Journal of the Neurological Sciences

出版年：2017

2.Use of T1-weighted/T2-weighted magnetic resonance ratio to elucidate changes due to amyloid β accumulation in cognitively normal subjects

作者：Fumihiko Yasuno^a ; ^e ; ^{ejm86rp@yahoo.co.jp} ; Hiroaki Kazui^b ; Naomi Morita^c ; Katsufumi Kajimoto^d ; Masafumi Ihara^d ; Akihiko Taguchi^f ; Akihide Yamamoto^e ; Kiwamu Matsuoka^a ; Masato Takahashi^a ; Jyoji Nakagawara^c ; Hidehiro Iida^e ; Toshifumi Kishimoto^a ; Kazuyuki Nagatsuka^d

关键词：Aβ ; amyloid beta ; AD ; Alzheimer's disease ; BP ; binding potential ; CSF ; cerebrospinal fluid ; FWHM ; full-width at half maximum ; MRI ; magnetic resonance imaging ; PET ; positron emission tomography ; PiB ; Pittsburgh Compound B ; PiB-BPND ; PiB-BP estimates relative to non-displaceable (ND) binding ; ROC ; receiver operating characteristic ; T1w ; T1-weighted ; T2w ; T2-weighted ; VOI ; volumes of interest

刊名：NeuroImage: Clinical

出版年：2017

3.Increased Levels of the Bullous Pemphigoid BP180 Autoantibody Are Associated with More Severe Dementia in Alzheimer’s Disease

作者：Nina Kokkonen¹ ; ⁴ ; Sanna-Kaisa Herukka² ; ⁴ ; Laura Huilaja¹ ; ⁴ ; Merja Kokki³ ; Anne M. Koivisto² ; Pä ; ivi Hartikainen² ; Anne M. Remes² ; Kaisa Tasanen¹ ; ^{kaisa.tasanen@oulu.fi}

关键词：Aβ1-42 ; beta-amyloid ; AD ; Alzheimer&rsquo ; s disease ; BP ; bullous pemphigoid ; CSF ; cerebrospinal fluid ; IF ; immunofluorescence ; MMSE ; mini-mental state examination ; NC16A ; noncollagenous 16A ; p-tau181 ; hyperphosphorylated tau

刊名：Journal of Investigative Dermatology

出版年：2017

4.Neurophysiological assessment of neural network plasticity and connectivity: Progress towards early functional biomarkers for disease interception therapies in Alzheimer’s disease

作者：C. Walsh ; W.H.I.M. Drinkenburg ; A. Ahnaou ; ^{aahnaou@its.jnj.com}

关键词：Aβ ; amyloid Beta ; ACh ; acetylcholine ; AChEI ; acetylcholinesterase inhibitor ; ACH ; amyloid cascade hypothesis ; AD ; Alzheimer&rsquo ; s disease ; APP ; amyloid precursor protein ; ARIA-E ; amyloid related imaging abnormalities related to edema ; CSF ; cerebrospinal fluid ; EEG ; electroencephalogram/electroencephalography ; EROS ; event-related oscillations ; ERP ; event-related potentials ; fAD ; familial Alzheimer&rsquo ; s disease ; fMRI ; functional MRI ; FTDP-17 ; frontotemporal dementia and parkinsonism linked to

刊名：Neuroscience & Biobehavioral Reviews

出版年：2017

5.Transcriptional and epigenetic phenomena in peripheral blood cells of monozygotic twins discordant for alzheimer’s disease, a case report

作者：Claudio D&rsquo ; Addario^a ; ^b ; ^{cdaddario@unite.it} ; Sussy Bastias Candia^c ; Beatrice Arosio^d ; ^e ; Martina Di Bartolomeo^a ; Carlo Abbate^e ; Alessandra Casè ; ^d ; Sanzio Candeletti^f ; Patrizia Romualdi^f ; Sarah Damanti^e ; ^g ; Mauro Maccarrone^b ; ^h ; ¹ ; Luigi Bergamaschini^d ; ⁱ ; ¹ ; Daniela Mari^d ; ^e ; ¹

关键词：AD ; Alzheimer&rsquo ; s Disease ; HADACs ; histone deacetylases ; APP ; amyloid precursor protein ; SIRT1 ; sirtuin 1 ; APOE ; apolipoprotein E ; PSEN1 ; presenilin 1 ; PIN1 ; peptidyl prolyl isomerase 1 ; PBMCs ; peripheral blood mononuclear cells ; DNMTs ; DNA methyltransferases ; Aβ ; Amyloid-β ; Ptau ; Phosphorylated tau ; CSF ; cerebrospinal fluid ; MCI ; Mild Cognitive Impairment ; H3K27me3 ; Histone 3 lysine 27 trimethylated ; H3K4me3 ; Histone 3 lysine 4 trimethylated ; H3K9Ac ; Histone 3 lysine 9 acetylated

刊名：Journal of the Neurological Sciences

出版年：2017

6.Clinical variables and biomarkers in prediction of cognitive impairment in patients with newly diagnosed Parkinson's disease: a cohort study

作者：Prof Anette Schrag ; FRCP^a ; ^{a.schrag@ucl.ac.uk} ; Uzma Faisal Siddiqui ; MSc^a ; Zacharias Anastasiou ; MSc^a ; Prof Daniel Weintraub ; MD^c ; ^d ; Jonathan M Schott ; FRCP^b

刊名：The Lancet Neurology

出版年：2017

7.Profiling the dynamics of CSF and plasma Aβ reduction after treatment with JNJ-54861911, a potent oral BACE inhibitor

作者：Maarten Timmers^a ; ^b ; ¹ ; Bianca Van Broeck^a ; ¹ ; Steven Ramael^c ; John Slemmon^d ; Katja De Waepenaert^a ; Alberto Russu^a ; Jennifer Bogert^e ; Hans Stieltjes^a ; Leslie M. Shaw^f ; Sebastiaan Engelborghs^b ; ^g ; Dieder Moechars^a ; Marc Mercken^a ; Enchi Liu^d ; Vikash Sinha^h ; John Kemp^a ; Luc Van Nueten^a ; Luc Tritsmans^a ; Johannes Rolf Streffer^a ; ^b ; ^{jstreffe@its.jnj.com" class="auth_mail" title="E-mail the corresponding author}

关键词：JNJ-54861911 ; Alzheimer's disease ; Amyloid β ; β-secretase enzyme ; BACE1 ; BACE inhibitors

刊名：Alzheimer's & Dementia: Translational Research & Clinical Interventions

出版年：2016

8.Default mode network connectivity is linked to cognitive functioning and CSF Aβ_1-42 levels in Alzheimer’s disease

作者：Ozlem Celebi^a ; Andac Uzdogan^b ; Kader Karli Oguz^c ; Arzu Ceylan Has^d ; Anil Dolgun^e ; Gul Yalcin Cakmakli^a ; Filiz Akbiyik^b ; Bulent Elibol^f ; Esen Saka^f ; ^{esensaka@hacettepe.edu.tr" class="auth_mail" title="E-mail the corresponding author}

关键词：Alzheimer&rsquo ; s disease ; Biomarker ; Cognition ; Resting functional magnetic resonance imaging ; Posterior cingulate cortex ; Retrosplenial cortex

刊名：Archives of Gerontology and Geriatrics

出版年：2016

9.Glial and neuronal markers in cerebrospinal fluid in different types of multiple sclerosis

作者：M.Alba Mañ ; é ; -Martí ; nez^a ; ^b ; ^{unitatem@bellvitgehospital.cat" class="auth_mail" title="E-mail the corresponding author} ; Bob Olsson^c ; Laura Bau^b ; Elisabet Matas^b ; Á ; lvaro Cobo-Calvo^b ; Ulf Andreasson^c ; Kaj Blennow^c ; Lucia Romero-Pinel^b ; Sergio Martí ; nez-Yé ; lamos^b ; ¹ ; Henrik Zetterberg^c ; ^d ; ¹

关键词：Aβ38 ; Aβ40 ; Aβ42 ; 38 ; 40 and 42 amino acid long fragments of amyloid β ; α-sAPP ; α-cleaved soluble amyloid-precursor protein ; β-sAPP ; β-cleaved soluble amyloid-precursor protein ; CIS ; Clinically isolated syndrome ; CNS ; Central nervous system ; CSF ; Cerebrospinal fluid ; EDMUS ; European database for multiple sclerosis ; EDSS ; Expanded disability status scale ; GFAP ; glial fibrillary acidic protein ; IDIBELL ; Bellvitge Biomedical Research Institute ; MCP-1 ; monocyte chemoattractant protein ; MS ; multiple

刊名：Journal of Neuroimmunology

出版年：2016

10.Electroconvulsive therapy selectively enhances amyloid β 1-42 in the cerebrospinal fluid of patients with major depression: A prospective pilot study

作者：Laura Kranaster^a ; ^{laura.kranaster@zi-mannheim.de} ; Suna Su Aksay^a ; Jan Malte Bumb^a ; Christoph Janke^b ; Angelika Alonso^c ; Carolin Hoyer^c ; Inga Zerr^d ; Matthias Schmitz^d ; Lucrezia Hausner^a ; Lutz Frö ; lich^a ; Alexander Sartorius^a

关键词：β-amyloid ; Electroconvulsive therapy ; ECT ; Cerebrospinal fluid ; CSF ; Alzheimer׳s disease ; Depression

刊名：European Neuropsychopharmacology

出版年：2016

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