搜索页_ DNA damage response (DDR)

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在“Elsevier电子期刊”中，命中：259条，耗时：0.0789635 秒

在所有数据库中总计命中：342条

1.DNA damage repair in breast cancer and its therapeutic implications

作者：Reem Ali¹ ; ² ; Emad A. Rakha¹ ; ² ; Srinivasan Madhusudan¹ ; ² ; Helen E. Bryant³ ; ^{h.bryant@sheffield.ac.uk}

关键词：DNA damage response ; breast cancer ; DDR ; defects ; therapeutic implications

刊名：Pathology

出版年：2017

2.Senescence as biologic endpoint following pharmacological targeting of receptor tyrosine kinases in cancer

作者：Paola Francica ; Daniel M. Aebersold ; Michaela Medová ; ; ^{michaela.medova@dkf.unibe.ch}

关键词：ATIR ; anti-tumor immune response ; ATM ; ataxia telangiectasia mutated ; CDK ; cyclin-dependent kinase ; CGH ; comparative genomic hybridization ; CHK1 ; checkpoint kinase 1 ; CHK2 ; checkpoint kinase 2 ; DDAs ; DNA-damaging agents ; DDR ; DNA damage response ; DSBs ; double-strand breaks ; EGF ; epidermal growth factor ; EGFR ; epidermal growth factor receptor ; EPHA3 ; EPH Receptor A3 ; FGFR ; fibroblast growth factor receptor ; FOXM1 ; Forkhead box protein M1 ; GAS6 ; growth arrest-specific protein 6 ; H3K9me3 ; histone 3

刊名：Biochemical Pharmacology

出版年：2017

3.The matrikine N-acetylated proline-glycine-proline induces premature senescence of nucleus pulposus cells via CXCR1-dependent ROS accumulation and DNA damage and reinforces the destructive effect of these cells on homeostasis of intervertebral discs

作者：Chencheng Feng¹ ; ^{doctorfgy@163.com} ; Yang Zhang¹ ; ^{65210796@qq.com} ; Minghui Yang¹ ; ^{doc_ymh@163.com} ; Minghong Lan¹ ; ^{fccdoc@me.com} ; Huan Liu¹ ; ^{20016040@163.com} ; Jian Wang¹ ; ^{tonywjxq@aliyun.com} ; Yue Zhou ; ¹ ; ^{happyzhou@vip.163.com} ; Bo Huang ; ¹ ; ^{fmmuhb@126.com}

关键词：IVD ; intervertebral disc ; IDD ; intervertebral disc degeneration ; SASP ; senescence-associated secreted phenotype ; NP ; nucleus pulposus ; AF ; annulus fibrosus ; SA-β-Gal ; senescence-associated β-galactosidase ; ECM ; extracellular matrix ; DDR ; DNA damage response ; N-Ac-PGP ; N-acetylated proline-glycine-proline ; RS ; replicative senescence ; Rb ; retinoblastoma protein ; RPX ; Reparixin ; ADAMTS ; a disintegrin and metalloproteinase with thrombospondin motifs ; MMP ; matrix metalloproteinase ; PE ; prolyl endopep

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

4.Aneuploidy of a murine immortalized endothelial cell line, MS1

作者：Kyoko Hida^a ; ^{khida@igm.hokudai.ac.jp} ; Nako Maishi^a ; Dorcas Akuba-Muhyia Annan^a ; Miyako Kondoh^a ; ^b ; Takayuki Hojo^a ; ^c ; Umma Habiba^a ; ^d ; Noritaka Ohga^a ; ^e ; Kosuke Ishikawa^a ; ^f ; Masumi Sato^a ; Chisaho Torii^a ; ^g ; Misa Yanagiya^a ; ^e ; Masahiro Morimoto^a ; ^e ; Yasuhiro Hida^h ; Masanobu Shindoh^d

关键词：Endothelial cell ; MS1 ; Aneuploidy ; DNA damage response

刊名：Journal of Oral Biosciences

出版年：2017

5.SEI1 induces genomic instability by inhibiting DNA damage response in ovarian cancer

作者：Jia You^a ; Jia Liu^a ; Yantao Bao^a ; Liqun Wang^a ; Yang Yu^a ; ^b ; Lei Wang^a ; ^c ; Di Wu^a ; Chang Liu^a ; Nan Wang^a ; Fei Wang^a ; Falin Wang^a ; Lu Xu^a ; Xing Tian^a ; Hongbin Liang^a ; Yating Gao^a ; Rongwei Guan^a ; Jing Bai^a ; Xiangning Meng^a ; Wenjing Sun^a ; Xin-Yuan Guan^d ; ^e ; Chunyu Zhang^a ; ^{zhangcy@ems.hrbmu.edu.cn} ; Songbin Fu^a ; ^f ; ^{fusb@ems.hrbmu.edu.cn} ; Yan Jin^a ; ^{jinyan@ems.hrbmu.edu.cn}

关键词：SEI1 ; SERTAD1 ; Genomic instability ; DDR ; Ovarian cancer

刊名：Cancer Letters

出版年：2017

6.Membrane damage by betulinic acid provides insights into cellular aging

作者：Waleska K. Martins^a ; ^b ; Andreza B. Gomide^c ; ^d ; É ; rico T. Costa^e ; Helena C. Junqueira^a ; Beatriz S. Stolf^f ; Rosangela Itri^c ; Maurí ; cio S. Baptista^a ; ^{baptista@iq.usp.br}

关键词：AAU ; Autophagy Arbitrary Units ; BA ; Betulinic Acid ; Cathepsin B ; CTSB ; CQ ; Chloroquine ; COXIV ; cytochrome c oxidase subunit iv ; CVS ; Crystal Violet Staining ; DMEM ; Dulbecco's modified Eagle's medium ; DDR ; DNA damage response ; FBS ; fetal bovine serum ; GAPDH ; Glyceraldehyde-3-Phosphate Dehydrogenase ; LMP ; Lysosomal membrane permeabilization ; MTT ; 3-(4 ; 5-Dimethylthiazol-2-yl)-2 ; 5-Diphenyltetrazolium Bromide ; NR ; Neutral Red ; OIS ; oncogene-induced senescence ; POPC ; 1-palmitoyl ; 2-oleoyl-sn-glycero-3-

刊名：Biochimica et Biophysica Acta (BBA) - General Subjects

出版年：2017

7.Reciprocal regulation of acetyl-CoA carboxylase 1 and senescence in human fibroblasts involves oxidant mediated p38 MAPK activation

作者：Iné ; s Marmisolle^a ; Jennyfer Martí ; nez^a ; Jie Liu^b ; Mauricio Mastrogiovanni^a ; Marí ; a M. Fergusson^b ; Ilsa I. Rovira^b ; Laura Castro^a ; André ; s Trostchansky^a ; Marí ; a Moreno^c ; Liu Cao^b ; ¹ ; Toren Finkel^b ; ^{finkelt@nhlbi.nih.gov} ; Celia Quijano^a ; ^{celiq@fmed.edu.uy}

关键词：Lipid synthesis ; Acetyl-CoA carboxylase 1 ; Cellular senescence ; DNA damage response ; Reactive oxygen species (ROS) ; p38 MAPK

刊名：Archives of Biochemistry and Biophysics

出版年：2017

8.Contributions of DNA repair and damage response pathways to the non-linear genotoxic responses of alkylating agents

作者：Joanna Klapacz^a ; ^{jklapacz@dow.com" class="auth_mail" title="E-mail the corresponding author} ; Lynn H. Pottenger^a ; ^b ; Bevin P. Engelward^c ; Christopher D. Heinen^d ; George E. Johnson^e ; Rebecca A. Clewell^f ; Paul L. Carmichael^g ; Yeyejide Adeleye^g ; Melvin E. Andersen^f

关键词：AAG ; alkyladenine DNA glycosylase ; ATM ; ataxia telangiectasia mutated ; BER ; base excision repair ; BPD ; break point dose ; BMD ; benchmark dose ; BMDL ; benchmark dose lower confidence limit ; CSBP ; computational systems biology pathway ; DSB ; double strand breaks ; DDR ; DNA damage response ; DRCs ; DNA repair centers ; EMS ; ethylmethanesulfonate ; ENU ; ethylnitrosourea ; FYDR ; fluorescent yellow direct repeat ; HR ; homologous repair ; MGMT ; methylguanine methyl transferase ; MMS ; methylmethane sulfonate ; MNNG

刊名：Mutation Research/Reviews in Mutation Research

出版年：2016

9.Systemic DNA damage responses in aging and diseases

作者：Flavia Ribezzo^a ; Yosef Shiloh^b ; Bjö ; rn Schumacher^a ; ^{bjoern.schumacher@uni-koeln.de" class="auth_mail" title="E-mail the corresponding author}

关键词：DNA repair ; DNA damage response ; Aging ; Cancer ; Nucleotide excision repair ; Ataxia-telangiectasia mutated ; Systemic DNA damage response

刊名：Seminars in Cancer Biology

出版年：2016

10.DNA mismatch repair and the DNA damage response

作者：Zhongdao Li¹ ; Alexander H. Pearlman¹ ; Peggy Hsieh ; ^{peggyh@niddk.nih.gov" class="auth_mail" title="E-mail the corresponding author}

关键词：Mismatch repair ; Lynch syndrome ; DNA damage response ; Mutagenesis ; Colorectal cancer

刊名：DNA Repair

出版年：2016

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