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作者：Yuanxia Huang ; ^{yuanxiahuangxx@163.com} ; Guang Wan ; Jingang Tao

关键词：OA ; osteoarthritis ; CTRP3 ; C1q/TNF-related protein-3 ; LPS ; lipopolysaccharide ; FGFs ; fibroblast growth factors ; EPCs ; endothelial progenitor cells ; SDF-1α ; stromal cell-derived factor 1α ; FGF-2 ; fibroblast growth factor-2 ; FGFR1 ; fibroblast growth factor receptor-1 ; MMP-1 ; matrix metalloproteinase-1 ; IL-1β ; interleukin 1β ; DMEM ; Dulbecco's modified Eagles's medium ; FBS ; fetal bovin serum ; PI3K ; phosphatidylinositol 3-kinase ; MTT ; 3-(4 ; 5-Dimethylthiazol-2-yl)-2 ; 5- diphenyltetrazolium bromide ; PI

刊名：Biomedicine & Pharmacotherapy

出版年：2017

2.Chronic Over-expression of Fibroblast Growth Factor 21 Increases Bile Acid Biosynthesis by Opposing FGF15/19 Action

作者：Jun Zhang^a ; Jamila Gupte^a ; Yan Gong^a ; Jennifer Weiszmann^a ; Yuan Zhang^c ; Ki Jeong Lee^b ; William G. Richards^b ; Yang Li^a ; ^{yangl@amgen.com}

关键词：FGF21 ; FGF19 ; βKlotho ; FGFR4 ; Bile acid metabolism

刊名：EBioMedicine

出版年：2017

3.FGF21 Is an Exocrine Pancreas Secretagogue

作者：Katie C. Coate¹ ; ⁴ ; ⁵ ; Genaro Hernandez¹ ; ⁴ ; Curtis A. Thorne¹ ; Shengyi Sun¹ ; Thao D.V. Le¹ ; Kevin Vale¹ ; Steven A. Kliewer¹ ; ² ; ^{steven.kliewer@utsouthwestern.edu} ; David J. Mangelsdorf¹ ; ³ ; ⁶ ; ^{davo.mango@utsouthwestern.edu}

关键词：FGF21 ; secretagogue ; exocrine pancreas ; CCK ; proteostasis ; β-Klotho ; acinar cell ; pancreatitis ; calcium signaling ; secretion

刊名：Cell Metabolism

出版年：2017

4.The effect of leptin, ghrelin, and neuropeptide-Y on serum Tnf-Α, Il-1β, Il-6, Fgf-2, galanin levels and oxidative stress in an experimental generalized convulsive seizure model

作者：Berrin Oztas^a ; Deniz Sahin^b ; ^{sahindeniztr@gmail.com} ; Hale Kir^c ; Fatma Ceyla Eraldemir^c ; Mert Musul^d ; Sevinç ; Kuskay^c ; Nurbay Ates^b

关键词：Leptin ; Ghrelin ; Neuropeptide-Y ; Tnf-Α ; Il-1β ; Il-6 ; Fgf-2 ; Galanin ; Oxidative stress ; Convulsive seizure model

刊名：Neuropeptides

出版年：2017

5.Sec8 modulates TGF-β induced EMT by controlling N-cadherin via regulation of Smad3/4

作者：Toshiaki Tanaka^a ; ^b ; ^{ttanaka@med.id.yamagata-u.ac.jp} ; Kaoru Goto^a ; Mitsuyoshi Iino^b

关键词：EMT ; epithelial-mesenchymal transition ; MET ; mesenchymal-epithelial transition ; TGF-β ; transforming growth factor-beta ; Smad ; drosophila mothers against decapentaplegic ; SBEs ; Smad binding elements ; CBP ; CREB binding protein ; siRNA ; small interfering RNA ; ChIP ; chromatin immunoprecipitation ; GAPDH ; glyceraldehyde-3-phosphate dehydrogenase ; ESRP ; epithelial splicing regulatory protein ; FGFR2 ; fibroblast growth factor receptor 2 ; Arp2/3 ; actin-related protein 2/3 ; 53BP1 ; p53-binding protein 1

刊名：Cellular Signalling

出版年：2017

6.Epithelial-mesenchymal-transition regulators in prostate cancer: Androgens and beyond

作者：Mary Nakazawa ; Natasha Kyprianou ; ^{nkypr2@uky.edu}

关键词：ADT ; Androgen deprivation therapy ; AR ; Androgen receptor ; CRPC ; Castration resistant prostate cancer ; DHT ; Dihydrotestosterone ; EGF ; Epidermal growth factor ; EMT ; Epithelial mesenchymal transition ; ERβ ; Estrogen receptor β ; FGF ; Fibroblast growth factor ; IGF ; Insulin-like growth factor ; MET ; Mesenchymal epithelial transition ; PDGF ; Platelet derived growth factor ; PI3 K ; Phosphatidylinositol 3-OH kinase ; PTEN ; Phosphatase tensin homolog ; RTK ; Receptor tyrosine kinase ; SHH ; Sonic Hedgehog ; TGFβ ; T

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：2017

7.In Vitro and In Vivo Activity of Lucitanib in FGFR1/2 Amplified or Mutated Cancer Models

作者：Federica Guffanti^* ; ³ ; Rosaria Chilà ; ^* ; ³ ; Ezia Bello^* ; Massimo Zucchetti^&dagger ; ; Monique Zangarini^&dagger ; ; Laura Ceriani^&dagger ; ; Mariella Ferrari^&dagger ; ; Monica Lupi^&dagger ; ; Anne Jacquet-Bescond^&Dagger ; ; Mike F. Burbridge^&Dagger ; ; Marie-Jeanne Pierrat^&Dagger ; ; Giovanna Damia^* ; ^{giovanna.damia@marionegri.it}

刊名：Neoplasia

出版年：2017

8.d-Psicose, a sugar substitute, suppresses body fat deposition by altering networks of inflammatory response and lipid metabolism in C57BL/6J-ob/ob mice

作者：Sung-Eun Kim^a ; ¹ ; ^{sekim702@gmail.com} ; Su Jeong Kim^a ; ¹ ; ^{ksj_0321@naver.com} ; Hye-Jung Kim^b ; ^{hyejung.kim@samyang.com} ; Mi-Kyung Sung^a ; ^{mksung@sm.ac.kr}

关键词：Abcd2 ; ATP-binding cassette ; sub-family D ; member 2 ; aP2 ; adipocyte protein 2 ; C/EBP-α ; CCAAT/enhancer-binding protein-alpha ; CPT-1 ; carnitine palmitoyltransferase-1 ; FAS ; fatty acid synthase ; FC ; fold change ; Fgf21 ; fibroblast growth factor 21 ; Fos ; FBJ murine osteosarcoma viral oncogene homolog ; HSL ; hormone-sensitive lipase ; IL-6 ; interleukin-6 ; LPL ; lipoprotein lipase ; MCP-1 ; monocyte chemoattractant protein-1 ; Mmp3 ; matrix metallopeptidase 3 ; PPAR-α ; peroxisome proliferator-activated recept

刊名：Journal of Functional Foods

出版年：2017

9.The binding of the bone morphogenetic protein antagonist gremlin to kidney heparan sulfate: Such binding is not essential for BMP antagonism

作者：Arnold Junior Tatsinkam^a ; ¹ ; Naomi Rune^a ; Joy Smith^a ; ² ; Jill T. Norman^b ; Barbara Mulloy^a ; Christopher C. Rider^a ; ^{c.rider@rhul.ac.uk}

关键词：BMP ; bone morphogenetic protein ; CAN ; Cerberus and DAN ; CKD ; chronic kidney disease ; DAN ; differentially screening selected gene abberative in neuroblastoma ; FGF ; fibroblast growth factor ; GAG ; glycosaminoglycan ; HS ; heparan sulfate ; MGR ; mutant gremlin ; TGFβ ; transforming growth factor beta ; VEGF ; vascular endothelial growth factor ; VEGFR2 ; VEGF receptor 2

刊名：The International Journal of Biochemistry & Cell Biology

出版年：2017

10.Inhibition of Wnt/β-catenin signaling suppresses bleomycin-induced pulmonary fibrosis by attenuating the expression of TGF-β1 and FGF-2

关键词：Alveolar epithelial type II cells (ATII cells) ; Lung resident mesenchymal stem cells (LR-MSCs) ; Transforming growth factor (TGF)-β1 ; Fibroblast growth factor (FGF)-2 ; Fibroblastic differentiation

刊名：Experimental and Molecular Pathology

出版年：2016

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