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Elsevier电子期刊(446)

在“Elsevier电子期刊”中，命中：446条，耗时：0.0509769 秒

在所有数据库中总计命中：446条

1.Pharmacokinetic/pharmacodynamic modeling of etoposide tumor growth inhibitory effect in Walker-256 tumor-bearing rat model using free intratumoral drug concentrations

作者：Maiara Cá ; ssia Pigatto^a ; ^b ; ^c ; Renatha Menti Roman^c ; Letizia Carrara^d ; André ; ia Buffon^a ; ^c ; Paolo Magni^d ; Teresa Dalla Costa^a ; ^c ; ^{dalla.costa@ufrgs.br}

关键词：W256 ; Walker-256 ; HPLC-UV ; high pressure liquid chromatography-ultraviolet ; PK/PD ; pharmacokinetic/pharmacodynamic ; popPK ; population pharmacokinetic ; TGI ; Tumor Growth Inhibition ; NAD ; Naï ; ve Average Data ; SAEM ; stochastic approximation expectation maximization ; GOF ; goodness-of-fit ; VPC ; visual predictive check ; AUC ; area under the curve

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

2.Evaluation of automated time-lapse microscopy for assessment of in vitro activity of antibiotics

作者：Wanchana Ungphakorn^a ; ^b ; Christer Malmberg^a ; Pernilla Lagerbä ; ck^a ; Otto Cars^a ; Elisabet I. Nielsen^b ; Thomas Tä ; ngdé ; n^a ; ^{thomas.tangden@medsci.uu.se}

关键词：Gram-negative bacteria ; PKPD ; Bacterial morphology ; oCelloScope ; Bioscreen C ; Time-kill experiments

刊名：Journal of Microbiological Methods

出版年：2017

3.General PK/PD approach in oncology

作者：Gerald Fetterly

刊名：Drug Metabolism and Pharmacokinetics

出版年：2017

4.A generic viral dynamic model to systematically characterize the interaction between oncolytic virus kinetics and tumor growth

作者：Melanie I. Titze^a ; Julia Frank^b ; Michael Ehrhardt^b ; Sigrun Smola^c ; Norbert Graf^b ; Thorsten Lehr^a ; ^{thorsten.lehr@mx.uni-saarland.de}

关键词：MD ; multiple dose ; NDV ; Newcastle disease virus ; OV ; oncolytic virus ; PV ; parvovirus ; RV ; reovirus ; SD ; single dose ; VDM ; viral dynamic model ; VPC ; visual predictive check

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

5.PK/PD analysis of a novel pH-dependent antigen-binding antibody using a dynamic antibody-antigen binding model

作者：Kenta Haraya^a ; ^{haraya.kenta@chugai-pharm.co.jp" class="auth_mail" title="E-mail the corresponding author} ; Tatsuhiko Tachibana^a ; Yuki Iwayanagi^b ; Atsuhiko Maeda^b ; Kazuhisa Ozeki^b ; Junichi Nezu^a ; Masaki Ishigai^b ; Tomoyuki Igawa^b

关键词：Monoclonal antibody ; pH-dependent antigen-binding ; FcRn ; TMDD ; PK/PD

刊名：Drug Metabolism and Pharmacokinetics

出版年：2016

6.Puntos de corte de dalbavancina y recomendaciones para el estudio de su actividad in vitro

作者：Rafael Cantó ; n^a ; ^b ; ^{rafael.canton@salud.madrid.org} ; Marí ; a Dí ; ez-Aguilar^a ; ^b ; Marí ; a Isabel Morosini^a ; ^b

关键词：Dalbavancina ; Lipoglucopé ; ptidos ; Punto de corte ; Valor subrogado

刊名：Enfermedades Infecciosas y Microbiología Clínica

出版年：2017

7.Modelling the PKPD of oxycodone in experimental pain ‿Impact of opioid receptor polymorphisms

作者：Rasmus Olsen^a ; David J.R. Foster^b ; Richard N. Upton^b ; Anne E. Olesen^a ; ^c ; Joy R. Ross^d ; ^e ; Joanne Droney^d ; ^e ; Hiroe Sato^e ; Asbjø ; rn M. Drewes^c ; ^f ; Mads Kreilgaard^a ; ^{mdkd@novonordisk.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Opioid receptor genes ; Oxycodone ; Experimental pain ; Population ; PKPD ; Analgesia

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

8.In vivo real time non invasive monitoring of brain penetration of chemicals with near-infrared spectroscopy: Concomitant PK/PD analysis

作者：Francesco Crespi^a ; ^{fm.crespi@libero.it" class="auth_mail" title="E-mail the corresponding author} ; Stefano Cattini^b ; ^{stefano.cattini@unimore.it" class="auth_mail" title="E-mail the corresponding author} ; Maurizio Donini^b ; ^{maurizio.donini@unimore.it" class="auth_mail" title="E-mail the corresponding author} ; Andrea Bandera^b ; ^{andrea.bandera@unimore.it" class="auth_mail" title="E-mail the corresponding author} ; Luigi Rovati^b ; ^{luigi.rovati@unimore.it" class="auth_mail" title="E-mail the corresponding author}

关键词：NIRS ; HbO2 ; Hb ; O2 ; CO2 ; Rat brain ; In vivo ; Non invasive ; PK/PD ; Brain penetration

刊名：Journal of Neuroscience Methods

出版年：2016

9.Quantitative prediction of human pharmacokinetics and pharmacodynamics of imigliptin, a novel DPP-4 inhibitor, using allometric scaling, IVIVE and PK/PD modeling methods

作者：Dongyang Liu^a ; Xifeng Ma^b ; Yang Liu^a ; Huimin Zhou^b ; Chongtie Shi^b ; Frank Wu^b ; Ji Jiang^a ; Pei Hu^a ; ^{pei.hu.pumc@aol.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Imigliptin ; Pharmacokinetics ; Pharmacodynamics ; Prediction ; First-in-human

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

10.PKPD modelling of PR and QRS intervals in conscious dogs using standard safety pharmacology data

作者：Linné ; a Bergenholm^a ; Teresa Collins^b ; Neil D. Evans^a ; Michael J. Chappell^a ; Joanna Parkinson^c

关键词：AIC ; Akaike information criterion ; BSV ; between subject variability ; BLQ ; below the limit of quantification ; CV ; cardiovascular ; ECG ; electrocardiogram ; hERG ; human ether-a-go-go-related gene channel ; hCav1.2 ; human cardiac calcium channel ; hNav1.5 ; human cardiac sodium channel ; LC&ndash ; MS/MS ; liquid chromatography with tandem mass spectroscopy ; LLQ ; lower limit of quantification ; M3 receptor ; Muscarinic acetylcholine receptor 3 ; PD ; pharmacodynamic ; PK ; pharmacokinetic ; PPB ; plasma protein bin

刊名：Journal of Pharmacological and Toxicological Methods

出版年：2016

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