搜索页_ Phosphatidylinositol 3-kinase (PI3K)

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在“Elsevier电子期刊”中，命中：1,728条，耗时：0.017999 秒

在所有数据库中总计命中：2,428条

1.Class I phosphatidylinositol 3-kinase inhibitors for cancer therapy

作者：Wennan Zhao^&dagger ; ; Yuling Qiu^&dagger ; ; Dexin Kong ; ^{kongdexin@tmu.edu.cn}

关键词：Phosphatidylinositol 3-kinase ; PI3K inhibitor ; Drug candidate ; Cancer therapy ; PI3K/mTOR selectivity ; Anticancer

刊名：Acta Pharmaceutica Sinica B

出版年：2017

2.Inhibition of Focal Adhesion Kinase on Hepatic Stellate-cell Adhesion and Migration

作者：Yan Wang ; MD ; PhD ; Junji Ma ; MD ; PhD ; Lei Chen ; MD ; PhD ; Xiao-Li Xie ; PhD ; Huiqing Jiang ; MD ; PhD ; ^{jianghuiqing1959@sina.com}

关键词：Hepatic stellate cells ; Adhesion ; Migration ; Focal adhesion kinase&ndash ; related nonkinase ; Phosphatidylinositol 3-kinase

刊名：The American Journal of the Medical Sciences

出版年：2017

3.Epigallocatechin-3-gallate inhibits adipogenesis through down-regulation of PPARγ and FAS expression mediated by PI3K-AKT signaling in 3T3-L1 cells

作者：Mengqing Wu^a ; ^b ; ¹ ; Dan Liu^a ; ^b ; ¹ ; Rong Zeng^a ; ^b ; ¹ ; Tao Xian^a ; ^b ; Yi Lu^a ; ^b ; Guohua Zeng^a ; ^b ; Zhangzetian Sun^c ; Bowei Huang^c ; Qiren Huang^a ; ^b ; ^{qrhuang@ncu.edu.cn}

关键词：4E-BP1 ; 4E-binding protein1 ; C/EBP ; CCAAT/ enhancer binding proteins ; EGCG ; epigallocatechin-3-gallate ; FAS ; fatty acid synthase ; FOXO1 ; forkhead box-O1 ; HFD ; high fat diet ; IGF ; insulin-like growth factor ; IR ; insulin resistance ; IRS1 ; insulin receptor substrate 1 ; MSCs ; mesenchymal stem cells ; PGC1 ; PPARγ coactivator 1 ; PI3K ; phosphatidylinositol 3 kinase ; PPARγ ; peroxisome proliferator activated receptor γ ; Rb ; retinoblastoma protein ; TG ; triglyceride ; TIF2 ; transcriptional intermediary facto

刊名：European Journal of Pharmacology

出版年：2017

4.Phosphoinositide 3-kinase γ ties chemoattractant- and adrenergic control of microglial motility

作者：Nadine Schneble^a ; ^{Nadine.Schneble@med.uni-jena.de} ; Caroline Schmidt^a ; ^{Caroline.Schmidt@med.uni-jena.de} ; Reinhard Bauer^a ; ^{Reinhard.Bauer@med.uni-jena.de} ; Jö ; rg P. Mü ; ller^a ; ^{Joerg.Mueller2@med.uni-jena.de} ; Shamci Monajembashi^b ; ^{shamci@fli-leibniz.de} ; Reinhard Wetzker^a ; ^{Reinhard.Wetzker@uni-jena.de}

关键词：Akt ; protein kinase Akt/PKB ; ATP ; Adenosine triphosphate ; C5a ; complement system component 5a ; C5aR ; complement system component 5a receptor ; cAMP ; Cyclic adenosine monophosphate ; DAPI ; 4&prime ; 6-diamidino-2-phenylindole ; HRP ; horseradish peroxidase ; PIP3 ; phosphatidylinositol (34 ; 5)-trisphosphate ; shRNA ; small hairpin RNA

刊名：Molecular and Cellular Neuroscience

出版年：2017

5.Lindersin B from Lindernia crustacea induces neuritogenesis by activation of tyrosine kinase A/phosphatidylinositol 3 kinase/extracellular signal-regulated kinase signaling pathway

作者：Lihong Cheng^a ; ¹ ; Ying Ye^a ; ¹ ; Lan Xiang^a ; Hiroyuki Osada^b ; Jianhua Qi^a ; ^{qijianhua@zju.edu.cn}

关键词：Lindernia crustacea ; Scrophulariaceae ; PC12 cells ; Cucurbitane triterpenoid ; Neuritogenic activity ; Signaling pathway

刊名：Phytomedicine

出版年：2017

6.Heterodimerisation between VEGFR-1 and VEGFR-2 and not the homodimers of VEGFR-1 inhibit VEGFR-2 activity

作者：Meng Cai^a ; Keqing Wang^a ; Colin E. Murdoch^a ; Yuchun Gu^a ; ^b ; Asif Ahmed^a ; ^{asif.ahmed@aston.ac.uk}

关键词：Vascular endothelial growth factor (VEGF) ; VEGF receptors ; Heterodimers ; Phosphatidylinositol 3-kinase (PI3K) ; Angiogenesis

刊名：Vascular Pharmacology

出版年：2017

7.Intracellular signaling modifications involved in the anti-inflammatory effect of 4-alkoxy-6,9-dichloro[1,2,4]triazolo[4,3-a]quinoxalines on macrophages

作者：Antonio J. Ruiz-Alcaraz^a ; ^ajruiz@um.es ; Marí ; a Tristá ; n-Manzano^a ; Antonio Guirado^b ; Jesú ; s Gá ; lvez^c ; Marí ; a Martí ; nez-Esparza^a ; Pilar Garcí ; a-Peñ ; arrubia^a ; ^{pigarcia@um.es}

关键词：ATF ; activating transcription factor ; CCM ; complete culture medium ; ERK ; extracellular signal-regulated kinase ; IKK ; IκB kinase ; IL-6 ; interleukin 6 ; JNK ; c-Jun N-terminal kinase ; LPS ; lipopolysaccharide ; MAPK ; mitogen-activated protein kinase ; NSAIDs ; non-steroidal anti-inflammatory drugs ; NFκB ; nuclear factor kappa-light-chain-enhancer of activated B cells ; PAMP ; pathogen-associated molecular patterns ; PI3K ; phosphatidylinositol 3-kinase ; PKB ; protein kinase B ; PRRs ; PAMP recognition receptors

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

8.Lucidone Promotes the Cutaneous Wound Healing Process via Activation of the PI₃K/AKT, Wnt/β-catenin and NF-κB Signaling Pathways

作者：Hsin-Ling Yang^a ; Yu-Cheng Tsai^b ; Mallikarjuna Korivi^a ; Chia-Ting Chang^a ; You-Cheng Hseu^b ; ^c ; ^{ychseu@mail.cmu.edu.tw}

关键词：CDK ; cyclin dependent kinase ; COX ; cyclooxygenase ; ECM ; extracellular matrix ; EMT ; epithelial-mesenchymal transition ; GSK3β ; glycogen synthase kinase 3 beta ; ICAM ; intercellular adhesion molecule ; iNOS ; inducible nitric oxide synthase ; LY294002 ; (4-morpholinyl)-8-phenyl-4H-l-benzopyran-4-one ; MMPs ; matrix metalloproteinases ; NF-κB ; nuclear factor κB ; PCNA ; proliferating cell nuclear antigen ; PI3K ; phosphatidylinositol 3-kinase ; Tcf/Lcf ; T-cell factor/lymphoid enhancer factor ; TGFβ ; transforming

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

出版年：2017

9.Quercetin attenuates high fructose feeding-induced atherosclerosis by suppressing inflammation and apoptosis via ROS-regulated PI3K/AKT signaling pathway

作者：Xue-Li Lu ; ¹ ; ^{luxli123@126.com} ; Cui-Hua Zhao¹ ; Xin-Liang Yao ; Han Zhang

关键词：Quercetin ; High fructose ; Atherosclerosis ; ROS ; PI3K/AKT

刊名：Biomedicine & Pharmacotherapy

出版年：2017

10.Claudin-5, -7, and -18 suppress proliferation mediated by inhibition of phosphorylation of Akt in human lung squamous cell carcinoma

作者：Risa Akizuki ; Shun Shimobaba ; Toshiyuki Matsunaga ; Satoshi Endo ; Akira Ikari ; ^{ikari@gifu-pu.ac.jp}

关键词：CLDNs ; claudins ; CA ; constitutively active ; DAPI ; 4&prime ; 6-diamidino-2-phenylindole ; DN ; dominant negative ; EGFR ; epidermal growth factor receptor ; ERK ; extracellular signal-regulated kinase ; LDH ; lactate dehydrogenase ; MAP ; mitogen-activated protein ; NSCLC ; non-small cell lung cancer ; PCR ; polymerase chain reaction ; PDK1 ; 3-phosphoinositide-dependent protein kinase-1 ; PI ; propidium iodide ; PI3K ; phosphatidylinositol-3 kinase ; PKA ; protein kinase A ; SCLC ; small cell lung cancer ; SDS-PAGE ; sodi

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

出版年：2017

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