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在“Elsevier电子期刊”中，命中：295条，耗时：0.0259822 秒

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1.Role of prefrontal cortical calcium-independent phospholipase A₂ in antinociceptive effect of the norepinephrine reuptake inhibitor antidepresssant maprotiline

作者：Wee-Siong Chew^a ; Suku-Maran Shalini^b ; ^c ; Federico Torta^c ; ^d ; Markus R. Wenk^c ; ^d ; ^e ; Christian Stohler^f ; Jin-Fei Yeo^g ; Deron R. Herr^a ; Wei-Yi Ong^b ; ^c ; ^{wei_yi_ong@nuhs.edu.sg}

关键词：DHA ; docosahexaenoic acid ; EDTA ; ethylenediaminetetraacetic acid ; EPA ; eicosapentaenoic acid ; iPLA2 ; calcium-independent phospholipase A2 ; MRM ; Multiple Reaction Monitoring ; NRI ; noradrenaline reuptake inhibitor ; PAG ; periaqueductal gray ; PFC ; prefrontal cortex ; PVDF ; polyvinylidene difluoride

刊名：Neuroscience

出版年：2017

2.rBaltMIP, a recombinant alpha-type myotoxin inhibitor from Bothrops alternatus (Rhinocerophis alternatus) snake, as a potential candidate to complement the antivenom therapy

作者：Norival A. Santos-Filho^a ; ^d ; ¹ ; Tiago S. Sousa^a ; ¹ ; Johara Boldrini-Franç ; a^a ; Ludier K. Santos-Silva^b ; Danilo L. Menaldo^a ; Flá ; vio Henrique-Silva^b ; Adé ; lia C.O. Cintra^a ; Helen J. Laure^e ; Carla C.N. Mamede^c ; Fá ; bio Oliveira^c ; Thalita B. Riul^a ; Marcelo Dias-Baruffi^a ; José ; C. Rosa^e ; Suely V. Sampaio^a ; ^{suvilela@usp.br}

关键词：Bothrops alternatus ; rBaltMIP ; Phospholipase A2 inhibitor ; αPLI

刊名：Toxicon

出版年：2016

3.Development of a potent 2-oxoamide inhibitor of secreted phospholipase A₂ guided by molecular docking calculations and molecular dynamics simulations

作者：Sofia Vasilakaki^a ; Efrosini Barbayianni^a ; Georgios Leonis^b ; Manthos G. Papadopoulos^b ; Thomas Mavromoustakos^a ; Michael H. Gelb^c ; George Kokotos^a ; ^{gkokotos@chem.uoa.gr" class="auth_mail" title="E-mail the corresponding author}

关键词：Docking ; Inhibitors ; Molecular dynamics ; 2-Oxoamides ; Secreted phospholipase A2

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

4.BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly

关键词：5-LO ; 5-lipoxygenase ; AA ; arachidonic acid ; COX ; cyclooxygenase ; cPLA2 ; cytosolic phospholipase A2 ; FLAP ; 5-lipoxygenase-activating protein ; fMLP ; N-formyl-methionyl-leucyl-phenylalanine ; H(P)ETE ; hydro(pero)oxyeicosatetraenoic acid ; HHT ; hydroxyheptadecatrienoic acid ; IL ; interleukin ; LPS ; lipopolysaccharide ; LT ; leukotriene ; mPGES-1 ; microsomal prostaglandin E2 synthase 1 ; MPO ; myeloperoxidase ; PG ; phosphate-buffered saline plus 1 ; mg/ml glucose ; PGC ; phosphate-buffered saline plus 1

刊名：Biochemical Pharmacology

出版年：2016

5.Structural and evolutionary insights into endogenous alpha-phospholipase A₂ inhibitors of Latin American pit vipers

作者：Maria Iná ; cia Estevã ; o-Costa^a ; ^b ; ¹ ; Carlos Alexandre H. Fernandes^c ; ¹ ; Maurí ; cio de Alvarenga Mudadu^a ; Gló ; ria Regina Franco^b ; Marcos Roberto M. Fontes^c ; ^{fontes@ibb.unesp.br" class="auth_mail" title="E-mail the corresponding author} ; Consuelo Latorre Fortes-Dias^a ; ^{consuelo.latorre@funed.mg.gov.br" class="auth_mail" title="E-mail the corresponding author}

关键词：Phospholipase A2 inhibitor ; PLI ; Phospholipase A2 ; PLA2 ; Viperidae ; Snake

刊名：Toxicon

出版年：2016

6.UCN enhances TGF-beta-mediated mitoinhibition of VSMCs via counteracting TGF-beta-induced cPLA2 expression and activation

作者：Chao Zhu ; Changchun Cao ; Xiaofei Wang ; Jie Yuan ; Lai Jin ; Shengnan Li ; ^{snli@njmu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Ast ; astressin ; cPLA2 ; cytosolic phospholipase A2 ; CRF ; corticotrophin-releasing factor ; CRFR ; corticotrophin-releasing factor receptor ; PYR ; pyrrophenone ; UCN ; urocortin ; mitoinhibition ; mitosis inhibition

刊名：International Journal of Biochemistry and Cell Biology

出版年：2016

7.Digitoxin enhances the growth inhibitory effects of thapsigargin and simvastatin on ER negative human breast cancer cells

作者：Linda Saxe Einbond^a ; ^b ; ^d ; ^e ; ¹ ; ^{Linda.Einbond@Lehman.cuny.edu" class="auth_mail" title="E-mail the corresponding author} ; Hsan-au Wu^a ; ² ; Cristinel Sandu^c ; ² ; Margaret Ford^a ; Jason Mighty^b ; Victoria Antonetti^b ; Stephen Redenti^b ; Hongbao Ma^a

关键词：DAG ; diacylglycerol ; D7 ; diospyrin diethylether ; ER ; endoplasmic reticulum ; FAP ; fibroblast activation protein ; HCC ; hepatocellular cancer ; HMGR ; HMG-CoA reductase ; IAP ; inhibitor of apoptosis ; IP3 ; inositol 14 ; 5-trisphosphate ; 4NQO ; 4-Nitroquinoline 1-oxide ; PSA ; prostate specific antigen ; PSMA ; prostate specific memory antigen ; PIP2 ; phosphatidylinositol-4 ; 5-bisphosphate ; PLC ; phospholipase C ; SERCA ; sarcoplasmic/Er Ca2 ; +-ATPase inhibitor ; DMBA ; dimethylbenzathracene ; TPA ; tetradecanoylp

刊名：Fitoterapia

出版年：2016

8.Endogenous secreted phospholipase A₂ group X regulates cysteinyl leukotrienes synthesis by human eosinophils

作者：Teal S. Hallstrand ; MD ; MPH^a ; ^{tealh@uw.edu" class="auth_mail" title="E-mail the corresponding author} ; Ying Lai ; PhD^a ; Kathryn A. Hooper ; BS^b ; Rob C. Oslund ; PhD^c ; William A. Altemeier ; PhD^a ; Gustavo Matute-Bello^a ; Michael H. Gelb ; PhD^c ; ^d

关键词：Eosinophil ; leukotriene ; phospholipase A2 ; mitogen-activated kinase ; asthma ; allergy

刊名：Journal of Allergy and Clinical Immunology

出版年：2016

9.Effects of Bothrops atrox venom and two isolated toxins on the human complement system: Modulation of pathways and generation of anaphylatoxins

作者：Danilo L. Menaldo ; ^{danmenaldo@yahoo.com.br} ; Carolina P. Bernardes ; Anna L. Jacob-Ferreira ; Cí ; ntia G. Nogueira-Santos ; Tania M. Casare-Ogasawara ; Luciana S. Pereira-Crott ; Suely V. Sampaio ; ^{suvilela@usp.br}

关键词：MP ; metalloprotease/Batroxase ; PLA2 ; phospholipase A2/BatroxPLA2 ; NHS ; normal human serum ; CP ; classical pathway ; LP ; lectin pathway ; AP ; alternative pathway ; FB ; Factor B ; C1-INH ; C1-Inhibitor

刊名：Molecular Immunology

出版年：2016

10.Membrane and inhibitor interactions of intracellular phospholipases A₂

作者：Varnavas D. Mouchlis ; Edward A. Dennis ; ^{edennis@ucsd.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Phospholipase A2 ; PAPC ; Catalytic cycle ; Allosteric regulation ; Eicosanoid pathway ; Molecular dynamics simulations ; DXMS

刊名：Advances in Biological Regulation

出版年：2016

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