搜索页_ Transforming growth factor-beta 1 (TGF-β1)

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1.Combined treatment with zingerone and its novel derivative synergistically inhibits TGF-β1 induced epithelial-mesenchymal transition, migration and invasion of human hepatocellular carcinoma cells

作者：Young-Joo Kim^a ; ^b ; Youngsic Jeon^b ; Taejung Kim^c ; Won-Chul Lim^d ; Jungyeob Ham^c ; Young Nyun Park^b ; Tae-Jin Kim^d ; Hyeonseok Ko^d ; ^{drug9054@naver.com} ; ^{drug9054@dankook.ac.kr}

关键词：Zingerone ; Epithelial&ndash ; mesenchymal transition (EMT) ; Transforming growth factor-beta 1 (TGF-β1) ; Hepatocellular carcinoma cancer ; Metastasis

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

2.Sterol Regulatory Element Binding Protein (SREBP)-1 is a novel regulator of the Transforming Growth Factor (TGF)-β receptor I (TβRI) through exosomal secretion

作者：Richard Van Krieken ; Guang Chen ; Bo Gao ; Jolene Read ; Hassan A. Al Saleh ; Renzhong Li ; Khalid Al-Nedawi ; Joan C. Krepinsky ; ^{krepinj@mcmaster.ca}

关键词：TGF-β1 ; transforming growth factor beta 1 ; SREBP-1 ; sterol regulatory element binding protein-1 ; TβRI ; TGF-β receptor I

刊名：Cellular Signalling

出版年：2017

3.Sec8 modulates TGF-β induced EMT by controlling N-cadherin via regulation of Smad3/4

作者：Toshiaki Tanaka^a ; ^b ; ^{ttanaka@med.id.yamagata-u.ac.jp} ; Kaoru Goto^a ; Mitsuyoshi Iino^b

关键词：EMT ; epithelial-mesenchymal transition ; MET ; mesenchymal-epithelial transition ; TGF-β ; transforming growth factor-beta ; Smad ; drosophila mothers against decapentaplegic ; SBEs ; Smad binding elements ; CBP ; CREB binding protein ; siRNA ; small interfering RNA ; ChIP ; chromatin immunoprecipitation ; GAPDH ; glyceraldehyde-3-phosphate dehydrogenase ; ESRP ; epithelial splicing regulatory protein ; FGFR2 ; fibroblast growth factor receptor 2 ; Arp2/3 ; actin-related protein 2/3 ; 53BP1 ; p53-binding protein 1

刊名：Cellular Signalling

出版年：2017

4.AAV-mediated gene delivery attenuates neuroinflammation in feline Sandhoff disease

作者：Allison M. Bradbury^a ; ^b ; ^&dagger ; ; ^{brada@upenn.edu} ; Tiffany A. Peterson^a ; ^&Dagger ; ; Amanda L. Gross^a ; Stephen Z. Wells^c ; Victoria J. McCurdy^a ; ^b ; ^§ ; ; Karen G. Wolfe^b ; John C. Dennis^b ; Brandon L. Brunson^b ; Heather Gray-Edwards^a ; Ashley N. Randle^a ; Aime K. Johnson^c ; Edward E. Morrison^b ; Nancy R. Cox^a ; ^d ; Henry J. Baker^a ; Miguel Sena-Esteves^e ; Douglas R. Martin^a ; ^b

关键词：AAV ; adeno-associated virus ; CNS ; central nervous system ; DCN ; deep cerebellar nuclei ; GFAP ; glial fibrillary acidic protein ; Hex ; β-N-acetylhexosaminidase ; Iba1 ; ionized calcium-binding protein 1 ; ICV ; intracerebroventricular ; IL-1β ; interleukin 1 beta ; MHC-II ; major histocompatibility complex II ; MIP-1α ; macrophage inflammatory protein-1 alpha ; PBMC ; peripheral blood mononuclear cell ; SD ; Sandhoff disease ; Sphk1 ; sphingosine kinase 1 ; TGFβ1 ; transforming growth factor beta 1 ; TNF-α ; tumor necr

刊名：Neuroscience

出版年：2017

5.Calcitonin induces collagen synthesis and osteoblastic differentiation in human periodontal ligament fibroblasts

作者：Yibo Wei¹ ; Qing Ye¹ ; Zhen Tang ; Gang Tian ; Qiang Zhu ; Haocheng Gao ; Dalin Wang ; ^{wang_dento@163.com} ; Zhizhong Cao ; ^{caozhizh2014@163.com}

关键词：ECM ; extracellular matrix ; PDLF ; periodontal ligament fibroblasts ; CT ; calcitonin ; GCF ; gingival crevicular fluid ; PPD ; probing pocket depth ; CAL ; clinical attachment level ; GI ; gingival index ; TGF-β1 ; transforming growth factor-beta 1 ; BMP ; bone morphogenetic protein ; Col I ; collagen type I ; Col III ; collagen type III

刊名：Archives of Oral Biology

出版年：2017

6.Emodin self-emulsifying platform ameliorates the expression of FN, ICAM-1 and TGF-β1 in AGEs-induced glomerular mesangial cells by promoting absorption

作者：Jiani Huang^a ; ^b ; Wenyan Gong^a ; ^b ; Zhiquan Chen^a ; ^b ; Junying Huang^a ; ^b ; Qiuhong Chen^a ; ^b ; Heqing Huang^a ; ^b ; ^{huangheq@mail.sysu.edu.cn} ; Chunshun Zhao^a ; ^{zhaocs@mail.sysu.edu.cn}

关键词：Emodin self-emulsifying ; Cellular uptake ; Advanced glycation-end products ; Glomerular mesangial cells ; Renal fibrosis

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

7.Anti-fibrotic effects of bone morphogenetic protein-7-modified bone marrow mesenchymal stem cells on silica-induced pulmonary fibrosis

作者：Xiaoli Li¹ ; Guoliang An¹ ; Yan Wang ; Di Liang ; Zhonghui Zhu ; Ximeng Lian ; Piye Niu ; Caixia Guo ; Lin Tian ; ^{tian_lin@163.com}

关键词：BMP-7 ; bone morphogenetic protein-7 ; BMSCs ; bone marrow mesenchymal stem cells ; BMP-7-BMSCs ; BMSCs overexpress the BMP-7 gene by lentivirus transduction ; FN ; fibronectin ; TGF-β1 ; transforming growth factor beta 1 ; SP-C ; epithelial marker surfactant protein-C ; AQP-5 ; aquaporin-5 ; MSC ; mesenchymal stem cell ; BAL ; bronchoalveolar lavage ; Bcl-2 ; B-cell lymphoma-2 ; HO-1 ; heme oxygenase-1 ; GFP ; green fluorescent protein

刊名：Experimental and Molecular Pathology

出版年：2017

8.Is molecular size a discriminating factor in hyaluronan interaction with human cells?

作者：Antonella D&rsquo ; Agostino ^{antonella.dagostino@unina2.it} ; Antonietta Stellavato ^{antonietta.stellavato@unina2.it} ; Luisana Corsuto ^{luisanacorsuto@hotmail.it} ; Paola Diana ^{paola.diana0@libero.it} ; Rosanna Filosa ^{rosanna.filosa@unina2.it} ; Annalisa La Gatta ^{annalisa.lagatta@unina2.it} ; Mario De Rosa ^{mario.derosa@unina2.it} ; Chiara Schiraldi ; ^{chiara.schiraldi@unina2.it} ; ^{schiraldi.chiara@gmail.com}

关键词：HHA ; high molecular weight ; LHA ; low molecular weight ; HaCat ; human keratinocytes cell line ; NaCl ; sodium chloride ; TGF-β1 ; transforming growth factor beta 1 ; TNFα ; tumor necrosis factor α ; DMEM ; Dulbecco&rsquo ; s Modified Eagle Medium ; qRT-PCR ; quantitative real time PCR ; PBS ; physiological buffer solution ; TLVM ; time-lapse video microscopy ; RNA ; ribonucleic acid ; cDNA ; complementary DNA ; FBS ; fetal bovine serum ; Mw ; molecular weight

刊名：Carbohydrate Polymers

出版年：2017

9.High glucose-induced Matrilin-2 expression in mouse mesangial cells was mediated by transforming growth factor beta 1 (TGF-β1)

作者：Shukun Zhang^a ; ¹ ; Menglan Zhang^a ; ¹ ; Hong Huang^b ; Shiying Zhou^a ; Yanshneg Du^c ; Xin Yi^c ; ^{xinyi@iupui.edu" class="auth_mail" title="E-mail the corresponding author} ; Junming Luo^a ; ^{jluo099@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Diabetic nephropathy ; Extracellular matrix ; Matrilin-2 ; Transforming growth factor beta 1

刊名：Biochemical and Biophysical Research Communications

出版年：2016

10.Transforming growth-beta 1 contributes to isoflurane postconditioning against cerebral ischemia-reperfusion injury by regulating the c-Jun N-terminal kinase signaling pathway

关键词：Isoflurane ; Postconditioning ; Transforming growth factor beta (TGF-β) ; c-Jun N-terminal kinase (JNK) ; Cerebral ischemia&ndash ; reperfusion injury ; Middle cerebral artery occlusion ; Hippocampus ; Neuroprotection

刊名：Biomedicine & Pharmacotherapy

出版年：2016

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