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Elsevier电子期刊(16)

在“Elsevier电子期刊”中，命中：16条，耗时：0.0309874 秒

在所有数据库中总计命中：26条

1.Metals and metastasis: Exploiting the role of metals in cancer metastasis to develop novel anti-metastatic agents

作者：Leyla Fouani¹ ; Sharleen V. Menezes¹ ; Mellow Paulson ; Des R. Richardson ; Zaklina Kovacevic ; ^{zaklina.kovacevic@sydney.edu.au}

关键词：CCBE1 ; collagen and calcium-binding EGF domains 1 ; CO ; carbon monoxide ; CSC ; cancer stem cell ; CTCs ; circulating tumor cells ; DpC ; di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone ; DpT ; di-2-pyridylketone thiosemicarbazone ; Dp44mT ; 2-pyridylketone 4 ; 4-dimethyl-3-thiosemicarbazone ; ECM ; extracellular matrix ; eIF3a ; eukaryotic initiation factor 3a ; EMT ; epithelial to mesenchymal transition ; EPC ; epithelial progenitor cells ; ER ; estrogen receptor ; FAK ; focal adhesion kinase ; HIF-1α ; hyp

刊名：Pharmacological Research

出版年：2017

2.Mechanism of the induction of endoplasmic reticulum stress by the anti-cancer agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT): Activation of PERK/eIF2α, IRE1α, ATF6 and calmodulin kinase

作者：Angelica M. Merlot^a ; ¹ ; Nurul H. Shafie^a ; ^b ; ¹ ; Yu Yu^a ; Vera Richardson^a ; Patric J. Jansson^a ; Sumit Sahni^a ; Darius J.R. Lane^a ; Zaklina Kovacevic^a ; Danuta S. Kalinowski^a ; ² ; ^{danutak@med.usyd.edu.au" class="auth_mail" title="E-mail the corresponding author} ; Des R. Richardson^a ; ² ; ^{d.richardson@med.usyd.edu.au" class="auth_mail" title="E-mail the corresponding author}

关键词：ASK1 ; apoptosis signal-regulating kinase 1 ; ATF4 ; activating transcription factor 4 ; ATF6 ; activating transcription factor 6 ; BiP ; binding immunoglobulin protein ; BSO ; buthionine sulfoximine ; Ca2+ ; calcium ; CaMKII ; Ca2+/calmodulin-dependent protein kinase II ; CHOP ; C/EBP homologous protein ; DFO ; desferrioxamine ; Dp2mT ; di-2-pyridylketone 2-methyl-3-thiosemicarbazone ; Dp44mT ; di-2-pyridylketone 4 ; 4-dimethyl-3-thiosemicarbazone ; DpT ; di-2-pyridylketone thiosemicarbazone ; eIF2α ; eukaryotic initiati

刊名：Biochemical Pharmacology

出版年：2016

3.The renaissance of polypharmacology in the development of anti-cancer therapeutics: Inhibition of the 鈥淭riad of Death鈥?in cancer by Di-2-pyridylketone thiosemicarbazones

作者：Patric J. Jansson¹ ; ^{patric.jansson@sydney.edu.au" class="auth_mail" title="E-mail the corresponding author} ; Danuta S. Kalinowski ; Darius J.R. Lane ; Zaklina Kovacevic ; Nicole A. Seebacher ; Leyla Fouani ; Sumit Sahni ; Angelica M. Merlot ; Des R. Richardson¹ ; ^{d.richardson@med.usyd.edu.au" class="auth_mail" title="E-mail the corresponding author}

关键词：Polypharmacology ; Metastasis ; Tumor growth ; Resistance ; Thiosemicarbazones ; DpC

刊名：Pharmacological Research

出版年：2015

4.Lysosomal membrane stability plays a major role in the cytotoxic activity of the anti-proliferative agent, di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT)

刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research

出版年：2016

5.Complex forming competition and in-vitro toxicity studies on the applicability of di-2-pyridylketone-4,4,-dimethyl-3-thiosemicarbazone (Dp44mT) as a metal chelator

作者：Anik贸 Ga谩l ; G谩bor Orgov谩n ; Zs贸fia Polg谩ri ; Andrea R茅ti ; Victor G. Mihucz ; Szilvia B艖sze ; Norbert Szoboszlai ; Christina Streli

关键词：Copper poisoning ; Iron chelator ; Cancer therapy ; TXRF ; Cobalt ; Metal transport

刊名：Journal of Inorganic Biochemistry

出版年：January, 2014

6.Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy

作者：Bernard A. Fang ; 沤aklina Kova膷evi膰 ; Kyung Chan Park ; Danuta S. Kalinowski ; Patric J. Jansson ; Darius J.R. Lane ; Sumit Sahni ; Des R. Richardson

关键词：Akt ; protein kinase B ; CPT-11 ; irinotecan ; CMT4D ; Charcot&ndash ; Marie&ndash ; Tooth disease ; type 4D ; DFO ; deferoxamine (or desferrioxamine B) ; DpC ; di-2-pyridylketone 4-cyclohexyl-4-methyl-3-thiosemicarbazone ; DpT ; di-2-pyridylketone thiosemicarbazone ; Dp44mT ; di-2-pyridylketone 4 ; 4-dimethyl-3-thiosemicarbazone ; ECM ; extracellular matrix ; ERG-1 ; v-ets avian erythroblastosis virus E26 oncogene homologue ; EGR1 ; early growth factor-1 ; ETS ; v-ets avian erythroblastosis virus E26 oncogene homologue 2

刊名：Biochimica et Biophysica Acta (BBA)/Reviews on Cancer

出版年：January, 2014

7.Expanding horizons in iron chelation and the treatment of cancer: Role of iron in the regulation of ER stress and the epithelial-mesenchymal transition

作者：Darius J.R. Lane ; Thomas M. Mills ; Nurul H. Shafie ; Angelica M. Merlot ; Rayan Saleh Moussa ; Danuta S. Kalinowski ; Zaklina Kovacevic ; Des R. Richardson ; ^{d.richardson@med.usyd.edu.au" class="auth_mail}

关键词：ASK1 ; apoptosis signal-regulating kinase 1 ; ATF4 ; activating transcription factor 4 ; ATF6 ; activating transcription factor 6 ; Bcl-2 ; B-cell lymphoma 2 ; BiP ; binding immunoglobulin protein ; bZIP ; basic leucine zipper ; CDK ; cyclin-dependent kinase ; CDKI ; CDK inhibitors ; CHOP ; C/EBP homologous protein ; DFO ; desferrioxamine ; dNTP ; deoxyribonucleotide triphosphate ; Dp44mT ; di-2-pyridylketone 4 ; 4-dimethyl-3- thiosemicarbazone ; eIF2伪 ; eukaryotic initiation factor 2伪 ; EMT ; epithelial&ndash ; mesenchymal

刊名：Biochimica et Biophysica Acta (BBA)/Reviews on Cancer

出版年：April, 2014

8.Antiproliferative activity and therapeutic implications of potassium tris(4-methyl-1-pyrazolyl) borohydride in hepatocellular carcinoma

作者：Huangtao Jin^a ; Zhongyu Xu^a ; Dongfeng Li^b ; ^{dfli@mail.ccnu.edu.cn" class="auth_mail} ; Jin Huang^a ; ^{huangjin@ecust.edu.cn" class="auth_mail}

关键词：DFO ; deferoxamine ; KTp4-Me ; potassium tris(4-methyl-1-pyrazolyl)-borohydride ; ROS ; reactive oxygen species ; HCC ; hepatocellular carcinoma ; DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; FBS ; fetal bovine serum ; MTT ; 3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide ; TBST ; tris buffered saline with Tween 20 ; BSA ; bovine serum albumin ; Dp44mT ; di-2-pyridylketone-4 ; 4-dimethyl-3-thiosemicarbazone ; Bp44mT ; 2-benzoylpyridine-4 ; 4-dimethyl-3-thiosemicarbazone

刊名：Chemico-Biological Interactions

出版年：25 April, 2014

9.The anticancer thiosemicarbazones Dp44mT and triapine lack inhibitory effects as catalytic inhibitors or poisons of DNA topoisomerase II¦Á

作者：Jack C. Yalowich^a ; ^b ; ¹ ; Xing Wu^c ; Rui Zhang^c ; Ragu Kanagasabai^a ; Marisa Hornbaker^b ; Brian B. Hasinoff^c ; ¹ ; ^{B_Hasinoff@UManitoba.ca}

关键词：Dp44mT ; Triapine ; Topoisomerase II¦Á ; Cell cycle analysis ; Iron ; Thiosemicarbazone

刊名：Biochemical Pharmacology

出版年：2012

10.The oncology drug elesclomol selectively transports copper to the mitochondria to induce oxidative stress in cancer cells

作者：Masazumi Nagai ; Nha H. Vo ; Luisa Shin Ogawa ; Dinesh Chimmanamada ; Takayo Inoue ; John Chu ; Britte C. Beaudette-Zlatanova ; Rongzhen Lu ; Ronald K. Blackman ; James Barsoum ; Keizo Koya ; Yumiko Wada ; ^{ywada@syntapharma.com}

关键词：ROS ; reactive oxygen species ; LDH ; lactate dehydrogenase ; BCS ; bathocuproinedisulfonic acid ; DLC ; delocalized lipophilic cations ; DSF ; disulfiram ; ATTM ; ammonium tetrathiomolybdate ; Dp44mT ; di-2-pyridylketone 44 ; -dimethyl-3-thiosemicarbazone ; ETC ; electr

刊名：Free Radical Biology and Medicine

出版年：2012

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