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在“Elsevier电子期刊”中，命中：337条，耗时：小于0.01 秒

在所有数据库中总计命中：474条

1.Modulation of mutant Huntingtin aggregates and toxicity by human myeloid leukemia factors

作者：Manisha Banerjee ; ¹ ; ^{manisha.banerjee@gmail.com} ; ^{manishab@barc.gov.in} ; Moumita Datta² ; Nitai P. Bhattacharyya ; ³ ; ^{nitai.bhattacharyya@gmail.com}

关键词：HTT ; Huntingtin ; MLF ; myeloid leukemia factor ; HD ; Huntington&rsquo ; s disease ; Poly Q ; polyglutamine ; GFP ; green fluorescent protein ; FRAP ; fluorescence recovery after photo bleaching ; RFI ; relative fluorescence intensity ; CREB ; cAMP response element-binding protein

刊名：The International Journal of Biochemistry & Cell Biology

出版年：2017

2.Hederagenin and α-hederin promote degradation of proteins in neurodegenerative diseases and improve motor deficits in MPTP-mice

作者：An-Guo Wu^a ; ¹ ; Wu Zeng^a ; ¹ ; Vincent Kam-Wai Wong^a ; Yi-Zhun Zhu^b ; Amy C.Y. Lo^c ; Liang Liu^a ; ^{lliu@must.edu.mo} ; Betty Yuen-Kwan Law^a ; ^{yklaw@must.edu.mo}

关键词：CHMs ; Chinese herbal medicines ; ATG ; autophagy-related proteins ; AD ; Alzheimer&rsquo ; s disease ; PD ; Parkinson&rsquo ; s disease ; AMPK ; 5&prime ; adenosine monophosphate-activated protein kinase ; mTOR ; mammalian target of rapamycin ; HD ; Huntington&rsquo ; s disease ; HH ; hedera helix ; PF ; petroleum ; MPTP ; 1-methyl-4-phenyl-123 ; 6-tetrahydropyridine ; EF ; ethylacetate fraction ; HTT ; huntingtin ; NF ; n-butanol ; GFP ; green fluorescent protein ; PE ; phosphatidylethanolamine ; AHS ; acid hydrolyzed solution ; CM

刊名：Pharmacological Research

出版年：2017

3.Modeling Huntington׳s disease with patient-derived neurons

作者：Virginia B. Mattis ; ^{Virginia.Mattis@cshs.org} ; Clive N. Svendsen

关键词：(HD) ; Huntington׳s disease ; (HTT) ; Huntingtin ; (mtHTT) ; mutant Huntingtin ; (polyQs) ; polyglutamine repeats ; (CNS) ; central nervous system ; (hESC) ; human embryonic stem cell ; (hiPSC) ; human induced pluripotent stem cell ; (polyQs) ; polyglutamine repeats ; (MSN) ; medium spiny neuron ; (LGE) ; lateral ganglionic eminence ; (MGE) ; medial ganglionic eminence ; (CGE) ; caudal ganglionic eminence ; (GABA) ; gamma-aminobutyric acid ; (EB) ; embryoid body ; (KOSR) ; knock-out serum replacer ; (Shh) ; sonic hedgehog ; (D

刊名：Brain Research

出版年：2017

4.Stimulation of autophagy by genistein reduces levels of mutant huntingtin in cellular models of Huntington disease

作者：Karolina Pierzynowska ; Jagoda Mantej ; Natalia Niedzialek ; Aleksandra Hac ; Grzegorz Wegrzyn

刊名：Molecular Genetics and Metabolism

出版年：2017

5.Mitochondrial cristae remodelling is associated with disrupted OPA1 oligomerisation in the Huntington's disease R6/2 fragment model

作者：Tanja Hering^a ; Kerstin Kojer^a ; Nathalie Birth^a ; Jaqueline Hallitsch^a ; Jan-Willem Taanman^b ; Michael Orth^a ; ^{michael.orth@uni-ulm.de}

关键词：OPA 1 oligomerisation ; Cristae integrity ; Fission and fusion ; Mitofilin ; Caspase 3

刊名：Experimental Neurology

出版年：2017

6.Recombinant Adeno Associated Viral (AAV) vector type 9 delivery of Ex1-Q138-mutant huntingtin in the rat striatum as a short-time model for in vivo studies in drug discovery

作者：Ilaria Ceccarelli¹ ; Pasquale Fiengo² ; Rosaria Remelli ; Vincenzo Miragliotta³ ; Lara Rossini⁴ ; Irene Biotti ; Alessandra Cappelli ; Lara Petricca⁵ ; Salvatore La Rosa⁶ ; Andrea Caricasole⁵ ; Giuseppe Pollio ; Carla Scali ; ^{carla.scali@outlook.com" class="auth_mail" title="E-mail the corresponding author}

关键词：HD ; Huntington's disease ; mHTT ; mutant Huntingtin ; rAAV ; recombinant Adeno Associated Virus ; LV ; lentivirus ; tNAA ; total N-Acetyl Aspartate ; Myo-Ins ; myoinositol ; GFP ; green fluorescent protein ; NeuN ; neuronal nuclei ; DARPP-32 ; dopamine- and cyclic AMP-regulated phosphoprotein ; ChAT ; choline acetyl transferase ; GFAP ; glial fibrillary acidic protein ; Iba-1 ; ionized calcium binding adaptor molecule 1 ; PBST ; phosphate buffered saline-Triton-X100 ; BSA ; bovine serum albumin ; DAB ; diaminobenzidine ; RO

刊名：Neurobiology of Disease

出版年：2016

7.Atypical ubiquitination by E3 ligase WWP1 inhibits the proteasome-mediated degradation of mutant huntingtin

作者：Li Lin^a ; Zhenzhen Jin^a ; Huiping Tan^a ; Qiaoqiao Xu^a ; Ting Peng^a ; ^b ; ^c ; ^{pengting@mail.hust.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; He Li^a ; ^b ; ^c ; ^{heli@mails.tjmu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Huntington's disease ; Huntingtin ; WWP1 ; E3 ligase ; Ubiquitin-proteasome system ; Ubiquitination

刊名：Brain Research

出版年：2016

8.Insulin and IGF-1 regularize energy metabolites in neural cells expressing full-length mutant huntingtin

作者：Luana Naia^a ; ^b ; ¹ ; Má ; rcio Ribeiro^a ; ¹ ; Joana Rodrigues^a ; ¹ ; Ana I. Duarte^a ; ^c ; Carla Lopes^a ; ^c ; Tatiana R. Rosenstock^a ; ^c ; Michael R. Hayden^d ; A. Cristina Rego^a ; ^b ; ^{a.cristina.rego@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; ^{arego@fmed.uc.pt" class="auth_mail" title="E-mail the corresponding author} ; ^{acrego@cnc.uc.pt" class="auth_mail" title="E-mail the corresponding author}

关键词：ADP ; adenosine diphosphate ; Akt ; protein kinase B ; AMP ; adenosine monophosphate ; ATL ; alanine aminotransferase ; ATP ; adenosine triphosphate ; Cr ; creatine ; DG ; 2-deoxy-d-glucose ; FBS ; fetal bovine serum ; GLUC ; glucose ; IGF-1 ; insulin-like growth factor 1 ; IR/IGF-1R ; insulin/IGF-1 receptor ; LDH ; lactate dehydrogenase ; HD ; Huntington's disease ; mHTT ; mutant huntingtin ; PC ; pyruvate carboxylase ; PCr ; phosphocreatine ; PDH ; pyruvate dehydrogenase ; PI-3K ; phosphoinositide 3-kinase

刊名：Neuropeptides

出版年：2016

9.Lycium barbarum polysaccharide attenuates the cytotoxicity of mutant huntingtin and increases the activity of AKT

作者：Fang Fang^a ; Ting Peng^a ; ^b ; ^c ; Shiming Yang^a ; Weixi Wang^a ; Yinong Zhang^a ; He Li^a ; ^b ; ^c ; ^{heli@mails.tjmu.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Huntington's disease ; Mutant huntingtin ; AKT ; Lycium barbarum polysaccharide

刊名：International Journal of Developmental Neuroscience

出版年：2016

10.Enhanced immune response to MMP3 stimulation in microglia expressing mutant huntingtin

作者：C. Connolly^a ; A. Magnusson-Lind^b ; G. Lu^a ; P.K. Wagner^a ; A.L. Southwell^a ; M.R. Hayden^a ; M. Bjö ; rkqvist^b ; B.R. Leavitt^a ; ^{bleavitt@cmmt.ubc.ca" class="auth_mail" title="E-mail the corresponding author}

关键词：ASO ; antisense oligonucleotide ; CSE ; control standard endotoxin ; FAAH ; fatty acid amide hydrolysis ; FRET ; Fö ; rster resonance energy transfer ; HD ; Huntington&rsquo ; s Disease ; INF-γ ; Interferon-γ ; LPS ; lipopolysaccharide ; MMP3 ; Matrix metalloprotease 3 ; MMPs ; Matrix metalloproteinases ; MSD ; Meso Scale Discovery ; MSN ; medium spiny neuron ; PET ; Positron emission tomography ; RAC ; raclopride ; RT ; room temperature ; TB ; terbium ; TIMPs ; tissue inhibitors of metalloproteinases

刊名：Neuroscience

出版年：2016

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