搜索页_ α/β hydrolase domain-6

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在“Elsevier电子期刊”中，命中：14条，耗时：0.0219885 秒

在所有数据库中总计命中：141条

1.PNPLA1 Deficiency in Mice and Humans Leads to a Defect in the Synthesis of Omega-O-Acylceramides

作者：Susanne Grond¹ ; Thomas O. Eichmann¹ ; Sandrine Dubrac² ; Dagmar Kolb³ ; ⁴ ; ⁵ ; Matthias Schmuth² ; Judith Fischer⁶ ; Debra Crumrine⁷ ; Peter M. Elias⁷ ; Guenter Haemmerle¹ ; Rudolf Zechner¹ ; Achim Lass¹ ; Franz P.W. Radner¹ ; ^{franz.radner@uni-graz.at}

关键词：ABHD5 ; α/β hydrolase domain containing 5 ; ω-O-AcylCers ; ω-O-acylceramides ; ARCI ; autosomal recessive congenital ichthyosis ; CLE ; corneocyte-bound lipid envelope ; FA ; fatty acid ; ω-OH-(Glc)Cers ; ω-hydroxy-(glucosyl)ceramides ; PNPLA1 ; patatin-like phospholipase domain-containing 1 ; qRT-PCR ; quantitative real-time reverse transcriptase-PCR

刊名：Journal of Investigative Dermatology

出版年：2017

2.α/β-Hydrolase Domain 6 in the Ventromedial Hypothalamus Controls Energy Metabolism Flexibility

作者：Alexandre Fisette¹ ; ² ; Stephanie Tobin¹ ; ² ; Lé ; a Dé ; carie-Spain¹ ; ³ ; Khalil Bouyakdan¹ ; ⁴ ; Marie-Line Peyot¹ ; S.R. Murthy Madiraju¹ ; Marc Prentki¹ ; ² ; ⁴ ; Stephanie Fulton¹ ; ² ; ^{stephanie.fulton@umontreal.ca" class="auth_mail" title="E-mail the corresponding author} ; Thierry Alquier¹ ; ⁴ ; ⁵ ; ⁶ ; ^{thierry.alquier@umontreal.ca" class="auth_mail" title="E-mail the corresponding author}

关键词：endocannabinoids ; 2-arachidonoylglycerol ; cannabinoid receptor 1 ; α/β-hydrolase-domain 6 ; ventromedial hypothalamus ; energy homeostasis ; thermogenesis ; obesity

刊名：Cell Reports

出版年：2016

3.Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human α/β-hydrolase domain containing 11 (ABHD11)

作者：Dina Navia-Paldanius^a ; ^{dina.navia-paldanius@uef.fi" class="auth_mail" title="E-mail the corresponding author} ; Jayendra Z. Patel^b ; Miriam Ló ; pez Navarro^a ; Hermina Jakupović^a ; Steffi Goffart^d ; Sanna Pasonen-Seppä ; nen^a ; Tapio J. Nevalainen^b ; Tiina Jä ; ä ; skelä ; inen^a ; ^c ; Tuomo Laitinen^b ; Jarmo T. Laitinen^a ; Juha R. Savinainen^a

关键词：ABHD11 ; LYPLA2 ; AFMID ; Serine hydrolases ; ABPP ; Inhibitor screening ; Homology modelling

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

4.Broad impact of deleting endogenous cannabinoid hydrolyzing enzymes and the CB1 cannabinoid receptor on the endogenous cannabinoid-related lipidome in eight regions of the mouse brain

作者：Emma Leishman^a ; Ben Cornett^b ; Karl Spork^b ; Alex Straiker^b ; Ken Mackie^a ; ^b ; Heather B. Bradshaw^a ; ^{hbbradsh@indiana.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：2-AG ; 2-arachidonoyl glycerol ; 2-LG ; 2-linoleoyl glycerol ; 2-OG ; 2-oleoyl glycerol ; AA ; arachidonic acid ; ABHD6 ; α/β hydrolase domain-6 ; ABHD12 ; α/β hydrolase domain-12 ; AEA ; N-arachidonoyl ethanolamine ; A-GABA ; N-arachidonoyl GABA ; A-Phe ; N-arachidonoyl phenylalanine ; A-Ser ; N-arachidonoyl serine ; A-Taur ; N-arachidonoyl taurine ; A-Tyr ; N-arachidonoyl tyrosine ; CER ; cerebellum ; COX ; cyclooxygenase ; CTX ; cortex ; CXCL2 ; chemokine (C-X-C motif) ligand 2 ; DEA ; N-docosahexaenoyl ethanolamine ; DSE/I

刊名：Pharmacological Research

出版年：2016

5.Endocannabinoids and endocannabinoid-related mediators: Targets, metabolism and role in neurological disorders

作者：Fabio Arturo Iannotti^a ; Vincenzo Di Marzo^a ; ; Stefania Petrosino^a ; ^b

关键词：2-AG ; 2-arachidonoyl-glycerol ; 2-MAGs ; monoacylglycerols ; 2-OG ; 2-oleoyl-glycerol ; Abhd4 ; α/β-hydrolase domain type-4 ; ABHD6 and 12 ; α/β-Hydrolase Domain Containing Protein 6 and 12 ; AC ; adenylyl cyclase ; AD ; Alzheimer's disease ; AEA ; N-arachidonoyl-ethanolamine (anandamide) ; ALIA ; Autacoid Local Inflammation Antagonism ; Aβ ; amyloid β-protein ; BDNF ; brain-derived neurotrophic factor ; cAMP ; cyclic adenosine monophosphate ; CB1 and CB2 ; cannabinoid receptors of type-1 and -2 ; CBD ; cannabidiol ; COX-

刊名：Progress in Lipid Research

出版年：2016

6.α/β-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes

作者：Shangang Zhao¹ ; Yves Mugabo¹ ; Gwynne Ballentine² ; Camille Attane¹ ; Jose Iglesias¹ ; Pegah Poursharifi¹ ; Dongwei Zhang¹ ; ⁵ ; Thuy Anne Nguyen¹ ; Heidi Erb¹ ; Raphael Prentki¹ ; Marie-Line Peyot¹ ; Erik Joly¹ ; Stephanie Tobin¹ ; Stephanie Fulton¹ ; J. Mark Brown³ ; S.R. Murthy Madiraju¹ ; ⁴ ; ^{murthy.madiraju@crchum.qc.ca" class="auth_mail" title="E-mail the corresponding author} ; Marc Prentki¹ ; ⁴ ; ^{marc.prentki@umontreal.ca" class="auth_mail" title="E-mail the corresponding author}

刊名：Cell Reports

出版年：2016

7.Crystal structure of methylesterase family member 16 (MES16) from Arabidopsis thaliana

作者：Hongmei Li^a ; ^{hmli@ibcas.ac.cn" class="auth_mail" title="E-mail the corresponding author} ; Hua Pu^a ; ^b

关键词：Arabidopsis thaliana ; Chlorophyll breakdown ; MES16 ; Demethylation ; α/β-hydrolase superfamily ; Catalytic triad

刊名：Biochemical and Biophysical Research Communications

出版年：2016

8.Lipidomics profile of a NAPE-PLD KO mouse provides evidence of a broader role of this enzyme in lipid metabolism in the brain

作者：Emma Leishman^a ; Ken Mackie^a ; ^b ; Serge Luquet^c ; Heather B. Bradshaw^a ; ^{hbbradsh@indiana.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：2-AG ; 2-arachidonyl glycerol ; 2-LG ; 2-linoleoyl glycerol ; ABHD4 ; α/β-hydrolase domain 4 ; AEA ; N-arachidonoyl ethanolamine (anandamide) ; A-Taur ; N-arachidonoyl taurine ; CER ; cerebellum ; COX ; cyclooxygenase ; CTX ; cortex ; DEA ; N-docosahexaenoyl ethanolamine ; eCB ; endogenous cannabinoid ; FAAH ; fatty acid amide hydrolase ; GABA ; gamma-amino butyric acid ; GDE1 ; glycerophosphodiesterase 1 ; HIPP ; hippocampus ; HYP ; hypothalamus ; KO ; knockout ; LEA ; N-linoleoyl ethanolamine ; MAGL ; monoacylglycerol lipase ; M

刊名：Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids

出版年：2016

9.Dysregulation of the endocannabinoid signaling system in the cerebellum and brainstem in a transgenic mouse model of spinocerebellar ataxia type-3

作者：Carmen Rodrí ; guez-Cueto^a ; ^b ; ^c ; Mariluz Herná ; ndez-Gá ; lvez^a ; ^b ; ^c ; ^d ; Cecilia J. Hillard^e ; Patricia Maciel^f ; ^g ; Luis Garcí ; a-Garcí ; a^h ; ⁱ ; Sara Valdeolivas^a ; ^b ; ^c ; Miguel A. Pozo^h ; ^j ; José ; A. Ramos^a ; ^b ; ^c ; Marí ; a Gó ; mez-Ruiz^a ; ^b ; ^c ; ^d ; ^{msgr@med.ucm.es" class="auth_mail" title="E-mail the corresponding author} ; Javier Ferná ; ndez-Ruiz^a ; ^b ; ^c ; ^{jjfr@med.ucm.es" class="auth_mail" title="E-mail the corresponding author}

关键词：ABHD12 ; α/β-hydrolase domain-containing 12 ; 2-AG ; 2-arachidonoylglycerol ; CNS ; Central Nervous System ; Ct ; threshold cycle ; DAGL ; diacylglycerol lipase ; FAAH ; fatty acid amide hydrolase ; [18F]FDG ; 2-deoxy-2-[18F]fluoro-D-glucose ; GLAST ; glutamate-aspartate transporter ; GLT-1 ; glutamate transporter-1 ; IL-1β ; interleukin-1β ; MAGL ; monoacylglycerol lipase ; MRI ; magnetic resonance image ; NAPE-PLD ; N-arachidonoylphosphatidylethanolamine phospholipase D ; NSE ; neuron-specific enolase ; OEA ; oleylethanol

刊名：Neuroscience

出版年：2016

10.Inhibitors of diacylglycerol lipases in neurodegenerative and metabolic disorders

作者：Freek J. Janssen ; Mario van der Stelt ; ^{m.van.der.stelt@chem.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author}

关键词：2-AG ; 2-arachidonoylglycerol ; ABPP ; activity-based protein profiling ; ABHD6 and ABHD12 ; α/β-hydrolase domain proteins 6 and 12 ; CB1R and CB2R ; cannabinoid receptors type 1 and 2 ; DAGLs ; sn-1 specific diacylglycerol lipases α and β ; FAAH ; fatty acid amide hydrolase ; MAGL ; monoacylglycerol lipase

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

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