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1.Crosstalk between different family members: IL27 recapitulates IFNγ responses in HCC cells, but is inhibited by IL6-type cytokines

作者：Catherine Rolvering^a ; ¹ ; ^{catherine.rolvering@uni.lu} ; Andreas D. Zimmer^a ; ¹ ; ^{andreas_zimmer@web.de} ; Ines Kozar^a ; ^{ineskozar91@gmail.com} ; Heike M. Hermanns^b ; ^{heike.hermanns@virchow.uni-wuerzburg.de} ; Elisabeth Letellier^d ; ^{elisabeth.letellier@uni.lu} ; Laurent Vallar^c ; ^{laurent.vallar@lih.lu} ; Petr V. Nazarov^c ; ^{petr.nazarov@lih.lu} ; Nathalie Nicot^c ; ^{nathalie.nicot@lih.lu} ; Auré ; lien Ginolhac^e ; ^{aurelien.ginolhac@uni.lu} ; Serge Haan^d ; ^{serge.haan@uni.lu} ; Iris Behrmann^a ; ^{iris.behrmann@uni.lu} ; Claude Haan^a ; ^{claude.haan@uni.lu}

关键词：IL27 ; IFNγ ; IL6-type cytokines ; Hepatocellular carcinoma ; STAT transcription factors ; SOCS3

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

出版年：2017

2.IL-15 receptor alpha as the magic wand to boost the success of IL-15 antitumor therapies: The upswing of IL-15 transpresentation

作者：Johan MJ Van den Bergh^a ; ^{johan.vandenbergh@uantwerpen.be} ; Eva Lion^a ; ^b ; Viggo FI Van Tendeloo^a ; Evelien LJM Smits^a ; ^b ; ^c

关键词：ALT-803 ; IL-15 mutant (whereby the amino acid asparagine at position 72 is substituted by an aspartic acid) ; + ; sushi domain IL-15Rα (Fig. 1) ; IL ; interleukin ; IL-15Rα ; interleukin-15 receptor alpha ; NK cells ; natural killer cells ; RLI ; IL-15 coupled with a linker to the soluble IL-15Rα sushi domain (Fig. 1)

刊名：Pharmacology & Therapeutics

出版年：2017

3.Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13Rα1 and IL-13Rα2

作者：B. Popovic¹ ; ^{popovicb@medimmune.com} ; J. Breed² ; D.G. Rees¹ ; M.J. Gardener¹ ; L.M.K. Vinall¹ ; B. Kemp¹ ; J. Spooner¹ ; J. Keen¹ ; R. Minter¹ ; F. Uddin³ ; G. Colice⁴ ; T. Wilkinson¹ ; T. Vaughan¹ ; R.D. May⁵

关键词：IL ; interleukin ; Th2 ; T helper type 2 ; PDB ; Protein Data Bank ; VH ; variable heavy ; VL ; variable light region ; CDR ; complementary-determining region ; FW ; framework ; PBS ; phosphate-buffered saline ; HPLC-SEC ; high-performance liquid chromatography&ndash ; size-exclusion chromatography ; HTRF ; homogeneous time resolved fluorescence

刊名：Journal of Molecular Biology

出版年：2017

4.Th9 cells and IL-9 in autoimmune disorders: Pathogenesis and therapeutic potentials

作者：Yaxiong Deng^a ; Zijun Wang^a ; Christopher Chang^b ; Liwei Lu^c ; Chak Sing Lau^d ; Qianjin Lu^a ; ^{qianlu5860@gmail.com}

关键词：IL ; interleukin ; TGF-β ; transforming growth factor β ; SLE ; systemic lupus erythematosus ; MS ; multiple sclerosis ; IBD ; inflammatory bowel diseases ; RA ; rheumatoid arthritis ; mAb ; monoclonal antibody ; IFN-γ ; interferon gamma ; TNF-α ; tumor necrosis factor alpha ; Tregs ; regulatory T cells ; EAE ; experimental autoimmune encephalitis ; ETS ; E26-transformation-specific ; STAT ; activators of transcription ; JAK ; Janus kinase ; NO ; nitric oxide ; LPS ; lipopolysaccharide ; ILC2 ; type II innate lymphoid cells ; RO

刊名：Human Immunology

出版年：2017

5.Asthma and rhinitis have different genetic profiles for IL13, IL17A and GSTP1 polymorphisms

作者：E.P. Resende^a ; ^{eresende@fmed.uc.pt} ; A. Todo-Bom^b ; ^d ; C. Loureiro^b ; A. Mota Pinto^c ; ^d ; B. Oliveiros^e ; L. Mesquita^a ; H.C. Silva^a ; ^d

关键词：Asthma ; Rhinitis ; Allergy ; IL4R ; IL13 ; IL17A ; GSTP1 ; Genetic polymorphism ; Genetic profile

刊名：Revista Portuguesa de Pneumologia (English Edition)

出版年：2017

6.Effect of Dezocine on IL-12 and IL-10 secretion and lymphocyte activation by culturing dendritic cells from human umbilical cord blood

作者：Chang Feng^a ; Man Feng^b ; Ran Jiao^c ; Dongyi Liu^a ; Yanwu Jin^a ; Xin Zhao^a ; ^{15953107775@163.com} ; Ruixue Xiao^b

关键词：Dezocine ; Dendritic cells ; Immunity ; IL-12 ; IL-10

刊名：European Journal of Pharmacology

出版年：2017

7.Immunoreactivities of NF-κB, IL-1β and IL-1R in the skin of Chinese brown frog (Rana dybowskii)

作者：Liqin Xi ; Ruiqi Hu ; Ting Guo ; Yuhan Wang ; Xia Sheng ; Yingying Han ; Zhengrong Yuan ; Qiang Weng ; Meiyu Xu ; ^{xumeiyu@bjfu.edu.cn}

关键词：IL-1β ; IL-1R1 ; NF-κB ; Rana dybowskii ; Skin

刊名：Acta Histochemica

出版年：2017

8.Are psoriasis and psoriatic arthritis the same disease? The IL-23/IL-17 axis data

作者：Lazaros I. Sakkas ; ^{lsakkas@med.uth.gr} ; Dimitrios P. Bogdanos

关键词：Biological ; IL-17 ; IL-23 ; Mouse model ; Pathogenesis ; Psoriasis ; Psoriatic arthritis

刊名：Autoimmunity Reviews

出版年：2017

9.GM-CSF and IL-4 produced by NKT cells inversely regulate IL-1β production by macrophages

作者：Sehee Ahn^b ; ¹ ; Dongjin Jeong^b ; ¹ ; Sae Jin Oh^b ; ¹ ; Jiye Ahn^b ; Seung Hyo Lee^d ; Doo Hyun Chung^a ; ^b ; ^c ; ^{doohyun@snu.ac.kr}

关键词：NKT cells ; Macrophages ; IL-1b ; GM-CSF ; IL-4

刊名：Immunology Letters

出版年：2017

10.Genetic variants in IL-6 and IL-10 genes and susceptibility to hepatocellular carcinoma in HCV infected patients

作者：Ikram Sghaier^a ; ^{sghaiere.ikram@gmail.com} ; Leila Mouelhi^b ; Noor A. Rabia^c ; Bano R. Alsaleh^c ; Ezzedine Ghazoueni^d ; Wassim Y. Almawi^c ; Besma Yacoubi Loueslati^a

关键词：Hepatitis C virus ; Hepatocellular carcinoma ; IL-6 ; IL-10

刊名：Cytokine

出版年：2017

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