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在“Elsevier”中，命中：1,199条，耗时：0.0419787 秒

1.Major furocoumarins in grapefruit juice II: Phototoxicity, photogenotoxicity, and inhibitory potency vs. cytochrome P450 3A4 activity

作者：Anastasia Messer ; Nicole Raquet ; Christiane Lohr ; Dieter Schrenk ; ^{schrenk@rhrk.uni-kl.de}

关键词：CYP ; cytochrome P450 ; DHB ; 6&prime ; 7&prime ; -dihydroxybergamottin ; EC50 ; effective concentration 50% ; HPRT ; hypoxanthine&ndash ; guanine phosphoribosyl transferase ; 5-MOP ; 5-methoxypsoralen ; PMEF ; photomutagenicity equivalency factor ; PMIEF ; Photo-Micronucl

刊名：Food and Chemical Toxicology

出版年：2012

2.Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506

作者：Javier Carbajo-Lozoya^a ; Marcel A. Mü ; ller^b ; Stephan Kallies^b ; Volker Thiel^c ; ^d ; Christian Drosten^b ; Albrecht von Brunn^a ; ^{vonbrunn@mvp.uni-muenchen.de}

关键词：EC50 ; 50%effective inhibitory concentration ; RLU ; relative light units

刊名：Virus Research

出版年：2012

3.Inhibitory effects of pectenotoxins from marine algae on the polymerization of various actin isoforms

作者：Suzanne C. Butler^a ; Christopher O. Miles^b ; Amna Karim^a ; Michael J. Twiner^a ; ^{mtwiner@umd.umich.edu}

关键词：ARfD ; acute reference dose ; APB ; actin polymerization buffer ; CI ; confidence intervals ; DSP ; diarrhetic shellfish poisoning ; DTX ; dinophysistoxin ; IC50 ; 50%inhibitory concentration ; OA ; okadaic acid ; PTX ; pectenotoxin ; SDS&ndash ; PAGE ; sodium dodecyl sulf

刊名：Toxicology in Vitro

出版年：2012

4.The in vitro antiviral property of Azadirachta indica polysaccharides for poliovirus

作者：Ligia Carla Faccin-Galhardi^a ; Kristie Aimi Yamamoto^a ; Sayani Ray^b ; Bimalendu Ray^b ; Rosa Elisa Carvalho Linhares^a ; Carlos Nozawa^a ; ^relin@uel.br

关键词：CC50 ; 50%cytotoxic concentration ; IC50 ; 50%inhibitory concentration ; SI ; selectivity index

刊名：Journal of Ethnopharmacology

出版年：2012

5.Synthesis, biological evaluation and 3D-QSAR studies of novel 4,5-dihydro-1H-pyrazole niacinamide derivatives as BRAF inhibitors

作者：Cui-Yun Li^a ; ^&dagger ; ; Qing-Shan Li^a ; ^&dagger ; ; Li Yan^a ; Xiao-Guang Sun^a ; Ran Wei^a ; Hai-Bin Gong^b ; ^{ghbxzh@yahoo.com.cn} ; Hai-Liang Zhu^a ; ^{zhuhl@nju.edu.cn}

关键词：BRAF ; V-RAF murine sarcoma viral oncogene homolog B1 ; BRAFV600E ; V600E mutant BRAF ; IC50 ; half maximal inhibitory concentration ; GI50 ; the concentration that causes 50%growth inhibition ; 3D-QSAR ; quantitative structure&ndash ; activity relationship

刊名：Bioorganic and Medicinal Chemistry

出版年：2012

6.Production of dipeptidyl peptidase IV inhibitory peptides from defatted rice bran

作者：Tadashi Hatanaka^a ; ^{hatanaka@bio-ribs.com} ; Yosikazu Inoue^b ; Jiro Arima^c ; Yuya Kumagai^a ; Hirokazu Usuki^a ; ^d ; Kayoko Kawakami^a ; Masayo Kimura^a ; Takafumi Mukaihara^a

关键词：DPP-IV ; dipeptidyl peptidase IV ; GLP-1 ; glucagon-like peptide-1 ; HPLC ; high-performance liquid chromatography ; IC50 ; half-maximal inhibitory concentration ; LAP ; leucine aminopeptidase ; LC&ndash ; MS ; HPLC&ndash ; mass spectrometry ; pNA ; p-nitroanilide ; RB ; ri

刊名：Food Chemistry

出版年：2012

7.In vitro antiprotozoal and cytotoxic activity of 33 ethonopharmacologically selected medicinal plants from Democratic Republic of Congo

作者：D. Musuyu Muganza^a ; B.I. Fruth^b ; J. Nzunzu Lami^a ; G.K. Mesia^a ; O.K. Kambu^a ; G.L. Tona^a ; R. Cimanga Kanyanga^a ; ^d ; ^{kanyanga.cimanga@ua.ac.be} ; P. Cos^c ; L. Maes^c ; S. Apers^d ; L. Pieters^d

关键词：CC50 ; cytotoxic concentration 50% ; DR Congo ; Democratic Republic of Congo ; HAT ; human African trypanosomiasis ; IC50 ; inhibitory concentration 50% ; WHO ; World Health Organisation

刊名：Journal of Ethnopharmacology

出版年：2012

8.Cholinestrase inhibitory effects of geranylated flavonoids from Paulownia tomentosa fruits

作者：Jung Keun Cho^a ; ^&dagger ; ; Young Bae Ryu^c ; ^&dagger ; ; Marcus J. Curtis-Long^b ; Hyung Won Ryu^a ; Heung Joo Yuk^a ; Dae Wook Kim^a ; Hye Jin Kim^a ; Woo Song Lee^c ; Ki Hun Park^a ; ^{khpark@gnu.ac.kr}

关键词：IC50 ; the inhibitor concentration leading to 50%activity loss ; Ki ; inhibition constant ; Km ; Michaelis&ndash ; Menten constant

刊名：Bioorganic and Medicinal Chemistry

出版年：2012

9.In vitro assessment of cytochrome P450 inhibition and induction potential of felotaxel (SHR110008)

作者：Yi Ding¹ ; YanYan Jia¹ ; ChengTao Lu ; WenXing Liu ; Jing Yang ; Ying Song ; YanRong Zhu ; Lin Yang ; LiKun Ding ; AiDong Wen ; ^{adwen-2004@hotmail.com}

关键词：Human hepatic cytochrome P450 ; CYP inhibition ; CYP induction ; Drug&ndash ; drug interactions ; Felotaxel ; SHR110008

刊名：Biomedicine and Pharmacotherapy

出版年：2012

10.Inhibitory effects of dietary flavonoids on purified hepatic NADH-cytochrome b5 reductase: Structure-activity relationships

作者：Haydar Ç ; elik^a ; ^{celik@erciyes.edu.tr} ; Mü ; berra Ko艧ar^b

关键词：Flavonoids ; Cytochrome b5 reductase ; Enzyme inhibition ; Structure&ndash ; activity ; IC50

刊名：Chemico-Biological Interactions

出版年：2012

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