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在“Elsevier”中，命中：425条，耗时：0.0109985 秒

1.Intestinal CYP3A4 and midazolam disposition in vivo associate with VDR polymorphisms and show seasonal variation

作者：Ranjit K. Thirumaran^a ; ¹ ; ¹² ; ^{Ranjit.thirumaran@stjude.org} ; Jatinder K. Lamba^b ; ² ; ¹² ; ^{lamba004@umn.edu} ; Richard B. Kim^c ; ³ ; ^{Richard.kim@lhsc.on.ca} ; Brad L. Urquhart^d ; ⁴ ; ^{brad.urquhart@schulich.uwo.ca} ; Jamie C. Gregor^e ; ⁵ ; ^{Jamie.gregor@lhsc.on.ca} ; Nilesh Chande^e ; ⁶ ; ^{nilesh.chande@lhsc.on.ca} ; Yiping Fan^f ; ⁷ ; ^{yiping.fan@stjude.org} ; An Qi^g ; ⁸ ; ^{qi.an@stjude.org} ; Cheng Cheng^g ; ⁹ ; ^{cheng.cheng@stjude.org} ; Kenneth E. Thummel^h ; ¹⁰ ; ^{thummel@u.washington.edu} ; Stephen D. Hallⁱ ; ¹¹ ; ^{hallst@lilly.com} ; Erin G. Schuetz^a ; ^{erin.schuetz@stjude.org}

关键词：CYP3A4 ; Vitamin D ; VDR ; Polymorphism ; Seasonal variation

刊名：Biochemical Pharmacology

出版年：2012

2.The suitability of rat hepatoma cell line H4IIE for evaluating the potentials of compounds to induce CYP3A23 expression

作者：Hisako Fujimura ; ^{fujimura.hisako@mk.mt-pharma.co.jp} ; Naoko Murakami ; Satoko Miwa ; Chinami Aruga ; Wataru Toriumi

关键词：CYP induction ; H4IIE cells ; TaqMan RT-PCR ; DNA microarray ; Cyp3a23/3a1 ; Pxr ; DEX ; Cloned cells

刊名：Experimental and Toxicologic Pathology

出版年：2012

3.Effect of chondroitin sulfate on turpentine-induced down-regulation of CYP1A2 and CYP3A6

作者：Mirela-Onita Iovu^a ; Lucie Hé ; roux^a ; Josep Vergé ; s^b ; Eulá ; lia Montell^b ; Jacques Paiement^c ; Patrick du Souich^a ; ^{patrick.du.souich@umontreal.ca}

关键词：Chondroitin sulfate ; Cytochrome P450 ; CYP1A2 ; CYP3A6 ; Inflammation ; NF-魏B

刊名：Carbohydrate Research

出版年：2012

4.Arsenic decreases RXR伪-dependent transcription of CYP3A and suppresses immune regulators in hepatocytes

作者：Trisha L. Noreault-Conti^a ; ^b ; ^d ; Abigail Fellows^a ; ^e ; Judith M. Jacobs^a ; ^c ; Heidi W. Trask^a ; ^f ; Stephen C. Strom^g ; Ronald M. Evans^h ; Steven A. Wrightonⁱ ; Peter R. Sinclair^a ; ^d ; ^f ; Jacqueline F. Sinclair^a ; ^d ; ^f ; Ralph C. Nichols^a ; ^c ; ^e ; ^{ralph.c.nichols@dartmouth.edu}

关键词：Arsenic ; Hepatocyte ; RXR-alpha ; CYP3A ; Inflammation

刊名：International Immunopharmacology

出版年：2012

5.CYP3A-mediated apoptosis of dauricine in cultured human bronchial epithelial cells and in lungs of CD-1 mice

作者：Hua Jin^a ; Shuijie Shen^a ; Xiaoyan Chen^b ; Dafang Zhong^b ; Jiang Zheng^a ; ^{jiang.zheng@seattlechildrens.org}

关键词：Dauricine ; GSH depletion ; Apoptosis ; CYP3A

刊名：Toxicology and Applied Pharmacology

出版年：2012

6.Genetic polymorphisms of the CYP3A4, CYP3A5, CYP3A7 and CYP1A2 among the Jordanian population

作者：Ghada Salameh^a ; ^{gsalameh79@gmail.com} ; Kamal Al. Hadidi^b ; ¹ ; ^{khadidi@ju.edu.jo} ; Mohammad El. Khateeb^b ; ^c ; ² ; ^{mkhateeb@ju.edu.jo}

关键词：SNP ; single nucleotide polymorphism ; bp ; base pair ; Kb ; kilobase ; EDTA ; ethylene diamine tetra acetic acid ; Dntps ; deoxyribonucleotides

刊名：Environmental Toxicology and Pharmacology

出版年：2012

7.Role of human CYP3A4 in the biotransformation of sorafenib to its major oxidized metabolites

作者：Sussan Ghassabian^a ; Tristan Rawling^a ; Fanfan Zhou^a ; Munikumar R. Doddareddy^b ; Bruce N. Tattam^c ; David E. Hibbs^b ; Robert J. Edwards^d ; Pei H. Cui^a ; Michael Murray^a ; ^{michael.murray@sydney.edu.au}

关键词：CYP ; cytochrome P450 ; FMO ; flavin-containing monooxygenase ; HPLC ; high-performance liquid chromatography ; LC&ndash ; MS/MS ; liquid chromatography&ndash ; tandem mass spectrometry ; TKI ; tyrosine kinase inhibitor

刊名：Biochemical Pharmacology

出版年：2012

8.Human PXR-mediated induction of intestinal CYP3A4 attenuates 1伪,25-dihydroxyvitamin D₃ function in human colon adenocarcinoma LS180 cells

作者：Xi Emily Zheng^a ; ¹ ; Zhican Wang^a ; Michael Z. Liao^a ; Yvonne S. Lin^a ; Margaret C. Shuhart^b ; Erin G. Schuetz^c ; Kenneth E. Thummel^a ; ^{thummel@u.washington.edu}

关键词：Cytochrome P450 3A4 ; TRPV6 ; 1伪 ; 25-Dihydroxyvitamin D3 ; Human pregnane X receptor ; Rifampin ; Osteomalacia

刊名：Biochemical Pharmacology

出版年：2012

9.Regulation and induction of CYP3A11, CYP3A13 and CYP3A25 in C57BL/6J mouse liver

关键词：CYP3A11 ; CYP3A13 ; CYP3A25 ; PXR ; RXRα ; CAR ; DEX ; Mouse ; Expression ; Induction

刊名：Archives of Biochemistry and Biophysics

出版年：2007

10.Effects of poloxamer 407-induced hyperlipidemia on the pharmacokinetics of carbamazepine and its 10,11-epoxide metabolite in rats: Impact of decreased expression of both CYP3A1/2 and microsomal epoxide hydrolase

作者：Young Sun Lee^a ; Young Woo Kim^b ; ^c ; Sang Geon Kim^b ; Inchul Lee^d ; Myung Gull Lee^a ; Hee Eun Kang^a ; ^{kanghe@catholic.ac.kr}

关键词：CBZ ; carbamazepine ; CBZ-E ; carbamazepine 10 ; 11-epoxide ; CBZ-D ; trans-10 ; 11-dihydoxyl-10 ; 11-dihydro-CBZ ; HL ; hyperlipidemic ; CYP ; cytochrome P450 ; mEH ; microsomal epoxide hydrolase ; HDL ; high-density lipoprotein ; LDL ; low-density lipoprotein ; AUC ; total ar

刊名：European Neuropsychopharmacology

出版年：2012

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