搜索页_ 尾-site APP cleaving enzyme 1

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Elsevier电子期刊(25)

在“Elsevier电子期刊”中，命中：25条，耗时：0.0639721 秒

在所有数据库中总计命中：43条

1.Geniposide attenuates insulin-deficiency-induced acceleration of 尾-amyloidosis in an APP/PS1 transgenic model of Alzheimer鈥檚 disease

作者：Yonglan Zhang^a ; ^b ; Fei Yin^b ; ^c ; ^{fyin@cqut.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Jianhui Liu^b ; ^c ; Zixuan Liu^c ; Lixia Guo^c ; Zhining Xia^a ; Jeffrey Zidichouski^d

关键词：A尾 ; 尾-amyloid ; AD ; Alzheimer&rsquo ; s disease ; BACE1 ; 尾-site APP cleaving enzyme ; 尾APP ; 尾-amyloid protein precursor ; GLP-1R ; glucagon-like peptide 1 receptor ; IDE ; insulin-degrading enzyme ; IR ; insulin receptor ; IRS1/2 ; insulin receptor substrate 1/2 ; PBS ; phosphate buffered solution ; PS1 ; presenilin 1 ; PVDF ; polyvinylidene difluoride ; STZ ; streptozotocin ; TBS ; tris buffered solution

刊名：Neurochemistry International

出版年：2015

2.Effects of BACE1 haploinsufficiency on APP processing and A尾 concentrations in male and female 5XFAD Alzheimer mice at different disease stages

作者：L. Devi^a ; M. Ohno^a ; ^b ; ^{mohno@nki.rfmh.org" class="auth_mail" title="E-mail the corresponding author}

关键词：A尾 ; amyloid-尾 ; ABC ; avidin&ndash ; biotin peroxidase complex ; AD ; Alzheimer&rsquo ; s disease ; AICD ; APP intracellular domain ; ANOVA ; analysis of variance ; APP ; amyloid precursor protein ; BACE1 ; 尾-site APP-cleaving enzyme 1 ; EDTA ; ethylenediaminetetraacetic acid ; FAD ; familial Alzheimer&rsquo ; s disease ; HEPES ; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid ; PBS ; phosphate-buffered saline ; PS1 ; presenilin 1 ; sAPP伪 ; 伪-secretase-cleaved soluble ectodomain of APP ; sAPP尾 ; 尾-secretase-cleaved soluble

刊名：Neuroscience

出版年：2015

3.The keystone of Alzheimer pathogenesis might be sought in A尾 physiology

作者：D. Puzzo^a ; ^{danypuzzo@yahoo.it" class="auth_mail" title="E-mail the corresponding author} ; W. Gulisano^a ; O. Arancio^b ; A. Palmeri^a

关键词：伪7-nAchRs ; alpha7 nicotinic acetylcholine receptors ; AA ; aminoacids ; A尾 ; Amyloid-beta peptide ; AD ; Alzheimer&rsquo ; s disease ; ADDLs ; A尾-derived diffusible ligands ; AICD ; amyloid precursor protein intracellular domain ; AID ; amyloid intracellular domain ; APP ; Amyloid Precursor Protein ; APOE ; apolipoprotein E ; BACE ; beta-site amyloid precursor protein cleaving enzyme ; CBP ; CREB-binding protein ; CREB ; cAMP response element-binding protein ; CTF ; carboxy-terminal fragments ; FAD ; Familial Alzheimer&rsq

刊名：Neuroscience

出版年：2015

4.Carnosic acid suppresses the production of amyloid-尾 1-42 and 1-43 by inducing an 伪-secretase TACE/ADAM17 in U373MG human astrocytoma cells

作者：Hidemi Yoshida^a ; ^{hidemi_yoshida@gakushikai.jp" class="auth_mail} ; ^{hidemiyo@cc.hirosaki-u.ac.jp" class="auth_mail} ; Pengfei Meng^a ; Tomoh Matsumiya^a ; Kunikazu Tanji^b ; Ryo Hayakari^a ; Fei Xing^a ; Liang Wang^a ; Kazushi Tsuruga^c ; Hiroshi Tanaka^c ; ^d ; Junsei Mimura^e ; Kunio Kosaka^f ; Ken Itoh^e ; Ippei Takahashi^g ; Tadaatsu Imaizumi^a

关键词：A尾 ; amyloid-尾 ; AD ; Alzheimer's disease ; ADAM ; a disintegrin and metalloproteinase ; APP ; amyloid precursor protein ; BACE1 ; 尾-site APP-cleaving enzyme-1 ; BCA ; bicinchoninic acid ; BSA ; bovine serum albumin ; CA ; carnosic acid ; CHAPS ; 3-[(3-Cholamidopropyl) dimethylammonio]propanesulfonate ; CHX ; cycloheximide ; DMEM ; Dulbecco's Modified Eagle's Medium ; DMSO ; dimethyl sulfoxide ; ECE1 ; endothelin-converting enzyme-1 ; ELISA ; enzyme-linked immumosorbent assay ; FBS ; fetal bovine serum ; HRP ; horseradish

刊名：Neuroscience Research

出版年：February, 2014

5.Effects of C-glycosylation on anti-diabetic, anti-Alzheimer鈥檚 disease and anti-inflammatory potential of apigenin

作者：Jae Sue Choi ; Md. Nurul Islam ; Md. Yousof Ali ; Eon Ji Kim ; Young Myeong Kim ; Hyun Ah Jung

关键词：ACh ; acetylthiocholine iodide ; AChE ; acetylcholinesterase ; AGEs ; advanced glycation endproducts ; AR ; aldose reductase ; ARI ; aldose reductase inhibitor ; AMT ; 2-amino-5 ; 6-dihydro-6-methyl-4H-1 ; 3-thiazine hydrochloride ; AD ; Alzheimer&rsquo ; s disease ; A尾 ; amyloid-尾 peptides ; NADPH ; 尾-nicotinamide adenine dinucleotide phosphate ; APP ; 尾-site amyloid precursor ; BACE1 ; 尾-site amyloid precursor cleaving enzyme 1 ; BCh ; butyrylthiocholine chloride ; BChE ; butyrylcholinesterase ; ChAT ; choline acetyltran

刊名：Food and Chemical Toxicology

出版年：February, 2014

6.Purification of pre-miR-29 by arginine-affinity chromatography

作者：Patrí ; cia Pereira^a ; Â ; ngela Sousa^a ; Joã ; o Queiroz^a ; Ilí ; dio Correia^a ; Ana Figueiras^a ; ^b ; Fani Sousa^a ; ^{fani.sousa@fcsaude.ubi.pt" class="auth_mail}

关键词：miRNA ; microRNA ; RNA ; ribonucleic acid ; mRNA ; messenger RNA ; RISC ; RNA-induced silencing complex ; AD ; Alzheimer's disease ; A尾 ; 尾-amyloid ; APP ; 尾-amyloid precursor protein ; BACE1 ; 尾-site APP-cleaving enzyme 1 ; SPE ; silica-based solid-phase extraction ; PCR ; polymerase chain reaction ; cDNA ; complementary DNA ; AC ; affinity chromatography ; RNases ; RNA degrading enzymes ; tRNA ; transfer RNA ; sRNA ; small RNA.

刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences

出版年：1 March, 2014

7.GSK3尾, CREB, and BDNF in peripheral blood of patients with Alzheimer's disease and depression

作者：Jan Pl谩ten铆k ; Zden臎k Fi拧ar ; Richard Buchal ; Roman Jir谩k ; Eva Kitzlerov谩 ; Martina Zv臎艡ov谩 ; Ji艡铆 Raboch

关键词：A尾 ; amyloid-尾 ; AD ; Alzheimer's disease ; Akt ; protein kinase B ; APP ; amyloid precursor protein ; BACE1 ; 尾-site APP-cleaving enzyme 1 ; BDNF ; brain-derived neurotrophic factor ; CGI-S ; Clinical Global Impression&mdash ; Severity scale ; CREB ; cAMP-response element-binding protein ; GDS ; Geriatric Depression Scale ; GSK3尾 ; glycogen synthase kinase-3尾 ; HPA ; hypothalamic&ndash ; pituitary&ndash ; adrenal axis ; HRSD-21 ; 21-item Hamilton Rating Scale for Depression ; ICD-10 ; International Statistical Classific

刊名：Progress in Neuro-Psychopharmacology and Biological Psychiatry

出版年：3 April, 2014

8.Excessive hydrogen peroxide enhances the attachment of amyloid 尾_1-42 in the lens epithelium of UPL rats, a hereditary model for cataracts

作者：Noriaki Nagai ; Yoshimasa Ito

关键词：ADAM10 ; A disintegrin and metalloprotease domain protease 10 ; A尾 ; amyloid 尾 ; APP ; amyloid precursor protein ; BACE1尾 ; site APP cleaving enzyme ; Ca2+ ; calcium ion ; DDC ; diethyldithiocarbamate ; DMSO ; dimethyl sulfoxide ; DSF ; disulfiram ; GSH ; glutathione ; GAPDH ; glyceraldehyde-3-phosophate dehydrogenase ; H2O2 ; hydrogen peroxide ; HP尾CD ; hydroxypropyl-尾-cyclodextrin ; HPMC ; hydroxypropylmethylcellulose ; iNOS ; inducible nitric oxide synthase ; LPO ; lipid peroxide ; PS ; presenilin ; SDS ; sodium dodecyl

刊名：Toxicology

出版年：6 January, 2014

9.Hydrogen sulfide improves spatial memory impairment and decreases production of A尾 in APP/PS1 transgenic mice

作者：Xuan-li He^a ; Ning Yan^b ; Hua Zhang^a ; Yun-wen Qi^a ; Li-juan Zhu^a ; Meng-jie Liu^a ; Yong Yan^a ; ^{ywxlh@aliyun.com" class="auth_mail}

关键词：Hydrogen sulfide ; Beta-site amyloid precursor protein cleaving enzyme 1 ; A disintegrin metalloprotease ; Presenilin 1 ; Amyloid beta ; Alzheimer&rsquo ; s disease

刊名：Neurochemistry International

出版年：February, 2014

10.The multi-functional drug tropisetron binds APP and normalizes cognition in a murine Alzheimer's model

作者：Patricia Spilman ; Olivier Descamps ; Olivia Gorostiza ; Clare Peters-Libeu ; Karen S. Poksay ; Alex ; er Matalis ; Jesus Campagna ; Alex ; er Patent ; Rammohan Rao ; Varghese John ; Dale E. Bredesen

关键词：AD ; Alzheimer's disease ; APP ; amyloid precursor protein ; A尾 ; amyloid beta ; sAPP伪 ; soluble amyloid precursor protein alpha ; sAPP尾 ; soluble amyloid precursor protein beta ; CHO7W ; Chinese hamster ovary cells stably transfected with human APP wildtype ; 伪7nAChR ; alpha 7 nicotinic acetylcholine receptor ; 5-HT3 ; 5-hydroxytryptophan 3 (receptor) ; GABA ; gamma-aminobutyic acid ; PONV ; post-operative nausea and vomiting ; MCI ; mild cognitive impairment ; BACE ; beta-site APP cleaving enzyme ; Jcasp ; juxtame

刊名：Brain Research

出版年：10 March, 2014

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