作者：Jenny Roy ; Michelle-Audrey Fournier ; René ; Maltais ; Lucie Carolle Kenmogne ; Donald Poirier ; ^{donald.poirier@crchul.ulaval.ca" class="auth_mail" title="E-mail the corresponding author}

关键词：AR ; androgen receptor ; A-diol ; 5伪-androstane-3伪 ; 17尾-diol ; A-dione ; 5伪-androstane-3 ; 17-dione ; 5-diol ; 5-androstene-3尾 ; 17尾-diol ; 4-dione ; 4-androstene-3 ; 17-dione ; ADT ; androsterone ; AUC ; area under curve ; CTX ; castrated ; CTL ; control ; DHEA ; dehydroepiandrosterone ; DHT ; dihydrotestosterone ; DMSO ; dimethyl sulfoxide ; E2 ; estradiol ; E1 ; estrone ; EDTA ; ethylenediaminetetraacetic acid ; GC ; gas chromatography ; IC50 ; half maximal inhibitory concentration ; P450c17 ; 17尾-hydroxylase/17 ; 20-lyase ; 17尾-HSD3 or

刊名：Journal of Steroid Biochemistry and Molecular Biology

出版年：2015

作者：Rosana Leiva^a ; Constantí ; Seira^b ; Andrew McBride^c ; Margaret Binnie^c ; F. Javier Luque^b ; Axel Bidon-Chanal^b ; Scott P. Webster^c ; Santiago Vá ; zquez^a ; ^{svazquez@ub.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Adamantane ; 11尾-HSD1 inhibitors ; Drug discovery ; Molecular modeling

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2015

作者：Ahmed S. Abdelsamie^a ; Emmanuel Bey^b ; Emanuele M. Gargano^a ; Chris J. van Koppen^b ; Martin Empting^c ; Martin Frotscher^a ; ^{m.frotscher@mx.uni-saarland.de" class="auth_mail" title="E-mail the corresponding author}

关键词：17尾-Hydroxysteroid dehydrogenase type 1 ; Interspecies differences ; Estrogen-dependent diseases ; Estrogen mimetics ; Non-steroidal inhibitors

刊名：European Journal of Medicinal Chemistry

出版年：2015

作者：Qingzhi Ji^a ; Jun Tan^a ; ^b ; ^{tanjunmail@126.com" class="auth_mail" title="E-mail the corresponding author} ; Liancai Zhu^a ; Deshuai Lou^a ; Bochu Wang^a ; ^{wangbc2000@126.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Immobilized enzyme ; Enzyme biocatalysis ; Biotransformations ; Enzyme activity ; 7伪-hydroxysteroid dehydrogenases ; 7尾-hydroxysteroid dehydrogenases ; Bile acid

刊名：Biochemical Engineering Journal

出版年：2016

作者：Carlos F. Lagos^a ; Andrea Vecchiola^a ; Fidel Allende^b ; Cristobal A. Fuentes^a ; Juan E. Tichauer^a ; Carolina Valdivia^a ; Sandra Solari^b ; Carmen Campino^a ; ^e ; Alejandra Tapia-Castillo^a ; Rene Baudrand^a ; ^e ; Pia Villarroel^c ; Mariana Cifuentes^c ; Gareth I. Owen^d ; Cristian A. Carvajal^a ; ^e ; Carlos E. Fardella^a ; ^e ; ^{cfardella@med.puc.cl" class="auth_mail}

关键词：11尾-HSD1 ; 11尾-hydroxysteroid dehydrogenase type 1 ; 11尾-HSD2 ; 11尾-hydroxysteroid dehydrogenase type 2 ; E ; cortisol ; F ; cortisone ; HPLC-MS/MS ; high performance liquid chromatography coupled with tandem mass spectrometry ; NADPH ; nicotinamide adenine dinucleotide phosphate reduced form ; MS ; metabolic syndrome ; BGA ; 18beta-glycyrrhetinic acid

刊名：Molecular and Cellular Endocrinology

出版年：25 March, 2014

作者：Brett Lomenick^a ; ^{blomenick@mednet.ucla.edu" class="auth_mail" title="E-mail the corresponding author} ; Heping Shi^b ; Jing Huang^a ; ^c ; ^d ; ^{jinghuang@mednet.ucla.edu" class="auth_mail" title="E-mail the corresponding author} ; Chuo Chen^b ; ^{chuo.chen@utsouthwestern.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：尾-Sitosterol ; 17尾-HSD4 ; E-Syt1 ; Target identification ; Phytosterol

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2015

作者：Xiang-Yang Ye ; David Yoon ; Stephanie Y. Chen ; Akbar Nayeem ; Rajasree Golla ; Ramakrishna Seethala ; Mengmeng Wang ; Timothy Harper ; Bogdan G. Sleczka ; Atsu Apedo ; Yi-Xin Li ; Bin He ; Mark Kirby ; David A. Gordon ; Jeffrey A. Robl

关键词：11尾-Hydroxysteroid dehydrogenase type 1 (11尾-HSD1) ; Enzyme inhibitor ; Structure&ndash ; activity relationships (SAR)

刊名：Bioorganic and Medicinal Chemistry Letters

出版年：15 January, 2014

作者：Abdullah Azmahani ; MSc^a ; ^b ; Yasuhiro Nakamura ; MD ; PhD^a ; ^{yasu-naka@patholo2.med.tohoku.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Yohei Ozawa ; MD ; PhD^a ; ^c ; Keely M. McNamara ; PhD^a ; Taku Fujimura ; MD ; PhD^d ; Takahiro Haga ; MD^d ; Akira Hashimoto ; MD^d ; Setsuya Aiba ; MD ; PhD^d ; Hironobu Sasano ; MD ; PhD^a

关键词：EMPD ; extramammary Paget disease ; 17尾-HSD5 ; 17尾-hydroxysteroid dehydrogenase type 5 ; 5伪-red1 ; 5伪-reductase type 1 ; 5伪-red2 ; 5伪-reductase type 2 ; AR ; androgen receptor ; ER ; estrogen receptor ; CK19 ; cytokeratin 19 ; FOXP1 ; forkhead box protein P1

刊名：Human Pathology

出版年：2015

作者：Francisco De Jesú ; s Andino^a ; ¹ ; Leon Grayfer^a ; ¹ ; Guangchun Chen^a ; ¹ ; V. Gregory Chinchar^b ; Eva-Stina Edholm^a ; Jacques Robert^a ; ^{jacques_robert@urmc.rochester.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：ANOVA ; One-Way Analysis of Variance ; BHK-21 ; baby hamster kidney-21 cells ; 尾HSD ; ORF 52L ; 尾-hydroxysteroid dehydrogenase ; DMEM ; Dulbecco壮s modified Eagle壮s medium ; FBS ; fetal bovine serum ; FV3 ; Frog Virus 3 ; IE ; immediate-early ; i.p. ; intraperitoneal injection ; MOI ; multiplicity of infection ; PFU ; plaque forming units ; p.i. ; post-infection ; qPCR ; quantitative real-time PCR ; RV ; Ranavirus ; vCARD ; ORF 64R ; Caspase Activation and Recruitment Domain-containing protein ; vIF-2伪 ; ORF 26R ; viral homolog

刊名：Virology

出版年：2015

作者：M. Martineau ; G. Papacleovoulou ; S. Abu-Hayyeh ; P.H. Dixon ; H. Ji ; R. Powrie ; L. Larson ; E.K. Chien ; C. Williamson

关键词：Placenta ; BeWo cells ; 11尾HSD2 ; Bile acid ; Cortisol ; Intrahepatic cholestasis of pregnancy

刊名：Placenta

出版年：January, 2014