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1.The structure of polymer carriers controls the efficacy of the experimental combination treatment of tumors with HPMA copolymer conjugates carrying doxorubicin and docetaxel

作者：Milada &Scaron ; í ; rová ; ^a ; ^{sirova@biomed.cas.cz} ; Jiří ; Strohalm^b ; Petr Chytil^b ; Ondřej Lidický ; ^b ; Jakub Tomala^a ; Blanka Ří ; hová ; ^a ; Tomá ; &scaron ; Etrych^b

关键词：Drug delivery ; HPMA ; Doxorubicin ; Docetaxel ; EPR effect ; Tumor microenvironment

刊名：Journal of Controlled Release

出版年：2017

2.Overcoming multidrug resistance via simultaneous delivery of cytostatic drug and P-glycoprotein inhibitor to cancer cells by HPMA copolymer conjugate

作者：Ladislav Sivak^a ; Vladimir Subr^b ; Jakub Tomala^a ; Blanka Rihova^a ; Jiri Strohalm^b ; Tomas Etrych^b ; Marek Kovar^a ; ^{makovar@biomed.cas.cz}

关键词：Multidrug resistance ; P-glycoprotein ; Doxorubicin ; Reversin 121 ; HPMA copolymer carrier ; Polymer-drug conjugate

刊名：Biomaterials

出版年：2017

3.Urinary 3-hydroxypropyl mercapturic acid (3-HPMA) concentrations in dogs with acute spinal cord injury due to intervertebral disc herniation

作者：A.M. Sangster^a ; ^b ; L. Zheng^b ; R.T. Bentley^a ; R. Shi^b ; ^c ; ^{riyi@purdue.edu} ; R.A. Packer^a ; ^b

关键词：Acrolein ; 3-Hydroxypropyl mercapturic acid ; Canine acute spinal cord injury ; Intervertebral disc herniation ; Lipid peroxidation

刊名：The Veterinary Journal

出版年：2017

4.Tumor-targeted micelle-forming block copolymers for overcoming of multidrug resistance

作者：Alena Braunová ; ^a ; Libor Kostka^a ; Ladislav Sivá ; k^b ; Lucie Cuchalová ; ^a ; Zuzana Hvězdová ; ^a ; Richard Laga^a ; Sergey Filippov^a ; Peter Černoch^a ; Michal Pechar^a ; Olga Janou&scaron ; ková ; ^a ; Milada &Scaron ; í ; rová ; ^b ; Tomá ; &scaron ; Etrych^a ; ^{etrych@imc.cas.cz}

关键词：Multidrug resistance ; P-glycoprotein inhibitor ; EPR effect ; HPMA copolymer ; Poly(propylene oxide) ; Micellar drug conjugate

刊名：Journal of Controlled Release

出版年：2017

5.Cathepsin S-cleavable, multi-block HPMA copolymers for improved SPECT/CT imaging of pancreatic cancer

作者：Wei Fan^a ; ^c ; ¹ ; Wen Shi^a ; ^c ; ¹ ; Wenting Zhang^a ; ^c ; Yinnong Jia^a ; ^c ; Zhengyuan Zhou^a ; ^c ; Susan K. Brusnahan^a ; ^c ; Jered C. Garrison^a ; ^b ; ^c ; ^d ; ^{jcgarrison@unmc.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Cathepsin S ; HPMA ; FRET imaging ; Mononuclear phagocyte system ; Pancreatic cancer ; SPECT/CT imaging

刊名：Biomaterials

出版年：2016

6.Biodegradable yolk-shell microspheres for ultrasound/MR dual-modality imaging and controlled drug delivery

作者：Peng Yang^a ; ^b ; Xianfu Luo^c ; Sheng Wang^d ; Fang Wang^a ; Chuanbing Tang^b ; Changchun Wang^a ; ^{ccwang@fudan.edu.cn} ; ^{ccwang2012@sina.com}

关键词：Yolk-shell structure ; Dual-modality ; Ultrasound imaging ; Magnetic resonance imaging (MRI) ; Controlled drug delivery

刊名：Colloids and Surfaces B: Biointerfaces

出版年：2017

7.Conjugates of HA2 with octaarginine-grafted HPMA copolymer offer effective siRNA delivery and gene silencing in cancer cells

作者：Moran Golan ; Valeria Feinshtein ; Ayelet David ; ^{ayeletda@bgu.ac.il}

关键词：AIBN ; 2 ; 2&rsquo ; azobis(isobutyronitrile) ; CPPs ; cell-penetrating peptides ; CQ ; chloroquine ; DMSO ; dimethylsulfoxide ; EPR ; enhanced permeability and retention ; FITC ; fluorescein-5-isothiocyanate ; FPLC ; fast protein liquid chromatography ; GG ; glycylglycine ; HA2 ; subunit of the influenza virus hemagglutinin ; HPMA ; N-(2-hydroxypropyl)methacrylamide ; MA-FITC ; 5-[3-(methacryloylaminopropyl)thioureidyl]fluorescein ; MA-GG-OH ; methacryloylglycylglycine ; MA-GG-ONp ; methacryloylglycylglycine p-nitrophenyl

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2016

8.The structure-dependent toxicity, pharmacokinetics and anti-tumour activity of HPMA copolymer conjugates in the treatment of solid tumours and leukaemia

关键词：HPMA ; Doxorubicin ; Structure ; Toxicity ; Anti-tumour activity

刊名：Journal of Controlled Release

出版年：2016

9.Indium-based and iodine-based labeling of HPMA copolymer-epirubicin conjugates: Impact of structure on the in vivo fate

作者：Libin Zhang^a ; Rui Zhang^a ; Jiyuan Yang^a ; Jiawei Wang^a ; Jindřich Kopeček^a ; ^b ; ^{jindrich.kopecek@utah.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：N-(2-hydroxypropyl)methacrylamide (HPMA) ; Epirubicin ; Polymer-drug conjugates ; Dual-radiolabeling ; Pharmacokinetics and biodistribution

刊名：Journal of Controlled Release

出版年：2016

10.Predictors of residual pulmonary hypertension after balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension

作者：Akihiro Tsuji^a ; Takeshi Ogo^a ; ^b ; ^{ogo.takeshi.hp@mail.ncvc.go.jp} ; Jin Ueda^a ; Shigefumi Fukui^a ; Yoshiaki Morita^c ; Tetsuya Fukuda^c ; Norifumi Nakanishi^a ; Hisao Ogawa^d ; Satoshi Yasuda^d

刊名：International Journal of Cardiology

出版年：2017

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