搜索页_ 4-dihydroxyphenylalanine (l-dopa)

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在“Elsevier电子期刊”中，命中：653条，耗时：小于0.01 秒

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1.Pharmaceutical development of novel lactate-based 6-fluoro-l-DOPA formulations

作者：Nunzio Denora^a ; ^{nunzio.denora@uniba.it} ; Angela Lopedota^a ; Modesto de Candia^a ; Saverio Cellamare^a ; Leonardo Degennaro^a ; Renzo Luisi^a ; Antonietta Mele^a ; Domenico Tricarico^a ; Annalisa Cutrignelli^a ; Valentino Laquintana^a ; Cosimo D. Altomare^a ; Massimo Franco^a ; Vincenzo Dimiccoli^b ; Anna Tolomeo^b ; Antonio Scilimati^a ; ^{antonio.scilimati@uniba.it}

关键词：6-Fluoro-l-dopa (F-DOPA) ; Positron emission tomography (PET) ; Formulation ; l-(+)-lactic acid ; pH-rate profile ; F-DOPA stability ; In vitro and in vivo studies

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

2.Inhibition kinetics and molecular simulation of p-substituted cinnamic acid derivatives on tyrosinase

作者：Yi Cui^a ; Yong-Hua Hu^a ; Feng Yu^a ; Jing Zheng^a ; Lin-Shan Chen^a ; Qing-Xi Chen^a ; ^b ; Qin Wang^a ; ^{qwang@xmu.edu.cn}

关键词：4-CCA ; 4-chlorocinnamic acid ; 4-ECA ; 4-ethoxycinnamic acid ; 4-NCA ; 4-nitrocinnamic acid ; DMSO ; dimethyl-sulfoxide ; L-Tyr ; L-tyrosine ; L-DOPA ; L-3 ; 4-Dihydroxyphenylalanine ; Km ; Michaelis-Menten constant ; KI ; equilibrium constant of the inhibitor combining with the free enzyme ; IC50 ; inhibitor concentration leading to a 50% loss of activity

刊名：International Journal of Biological Macromolecules

出版年：2017

3.Involvement of presynaptic 5-HT_1A receptors in the low propensity of brexpiprazole to induce extrapyramidal side effects in rats

作者：Cedric Mombereau^a ; ^{CMOM@lundbeck.com} ; Jø ; rn Arnt^b ; Arne Mø ; rk^a

关键词：ANOVA ; Analysis of variance ; DA ; Dopamine ; EPS ; Extrapyramidal side effects ; l-DOPA ; l-3 ; 4-dihydroxyphenylalanine ; mPFC ; Medial prefrontal cortex ; 5-HT ; Serotonin

刊名：Pharmacology Biochemistry and Behavior

出版年：2017

4.Modifying effects of carboxyl group on the interaction of recombinant S100A8/A9 complex with tyrosinase

作者：Fatemeh NematiNiko^a ; Koorosh Goodarzvand Chegini^b ; Hamideh Asghari^c ; Abbas Amini^d ; ^{a.amini@westernsydney.edu.au} ; Nematollah Gheibi^e ; ^{ngheibi@qums.ac.ir}

关键词：MT ; mushroom tyrosinase ; L-DOPA ; L-3 ; 4-dihydroxyphenylalanine ; DOPA ; 3 ; 4-dihydroxyphenyl alanine ; r ; recombinant ; PPI ; protein-protein interaction ; CD ; circular dichroism spectroscopy ; NMR ; nuclear magnetic resonance ; WRK ; Woodward's reagent K ; UV-CD ; far ultraviolet circular dichroism spectrum ; IPTG ; isopropyl β-D-1-thiogalactopyranoside ; ANS ; anilinonaphthalene-8-sulfonic acid ; SDS-PAGE ; Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis ; PBS ; phosphate buffered solutions.

刊名：Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

出版年：2017

5.Melatonin regulates catecholamine biosynthesis by modulating bone morphogenetic protein and glucocorticoid actions

作者：Motoshi Komatsubara^a ; Takayuki Hara^a ; Takeshi Hosoya^a ; Kishio Toma^a ; Naoko Tsukamoto-Yamauchi^a ; Nahoko Iwata^b ; Kenichi Inagaki^a ; Jun Wada^a ; Fumio Otsuka^b ; ^{fumiotsu@md.okayama-u.ac.jp}

关键词：ActRI ; activin type-I receptor ; ActRII ; activin type-II recepto ; ALK ; activin receptor-like kinase ; AR ; androgen receptor ; BMP ; bone morphogenetic protein ; BMPRI ; BMP type-I receptor ; BMPRII ; BMP type-II receptor ; DBH ; dopamine-β-hydroxylase ; DDC ; 3 ; 4-dihydroxyphenylalanine decarboxylase ; DHT ; dihydrotestosterone ; GR ; glucocorticoid receptor ; MT ; melatonin receptor ; MR ; mineralocorticoid receptor ; PKA ; protein kinase A ; PNMT ; phenylalanine N-methyltrasferase ; TGF ; transforming growth factor ; TH

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：2017

6.Effects of different inundation periods on soil enzyme activity in riparian zones in Lijiang

作者：Yuqing Geng^a ; ^{gengyuqing@bjfu.edu.cn} ; Dongmei Wang^b ; ^{dmwang@bjfu.edu.cn} ; Wenbin Yang^a

关键词：AK ; Available potassium ; ALP ; Alkaline phosphatase ; AP ; Acid phosphatase ; ARS ; Arylsulfatase ; BGL ; β-Glucosidase ; CV ; Coefficient of variation ; DFA ; Discriminant function analysis ; DHA ; Dehydrogenase ; DOC ; Dissolved organic carbon ; DOM ; Dissolved organic matter ; DON ; Dissolved organic nitrogen ; DOPA ; l-Dihydroxyphenylalanine ; DTN ; Dissolved total nitrogen ; DX ; Daxu ; GAP ; Glycine aminopeptidase ; INTF ; Iodonitrotetrazolium formazan ; LAP ; l-Leucine aminopeptidase ; LJC ; Lijiaocun ; NAG ; β-N-acetylglu

刊名：CATENA

出版年：2017

7.Both a PKS and a PPTase are involved in melanin biosynthesis and regulation of Aureobasidium melanogenum XJ5-1 isolated from the Taklimakan desert

作者：Hong Jiang^a ; Guang-Lei Liu^a ; Zhe Chi^a ; Jian-Ming Wang^b ; Ly-Ly Zhang^b ; Zhen-Ming Chi^a ; ^{zhenming@sdu.edu.cn}

关键词：PKS ; polyketide synthase ; PPTase ; phosphopantetheinyl transferases ; NRPS ; nonribosomal peptide synthetase ; NPG1 ; the gene encoding a PPTase ; UV ; ultraviolet ; DHN ; dihydroxynaphthalene ; l-DOPA ; l-3 ; 4-dihydroxyphenylalanine ; THN ; tetrahydroxynaphthalene ; KS ; β-ketoacyl synthase ; AT ; acetyl transferase ; ACP ; acyl carrier proteins ; TE ; thioesterase ; CYC ; cyclase (CYC) ; ER ; enoyl reductase ; DH ; dehydratase ; KR ; keto-reductase

刊名：Gene

出版年：2017

8.Effect of Cd²⁺ on tyrosinase: Integration of inhibition kinetics with computational simulation

作者：Li-Mei Yue^a ; ¹ ; Jinhyuk Lee^b ; ^c ; ¹ ; Zhi-Rong Lü ; ^d ; Jun-Mo Yang^e ; Zhuo-Ming Ye^a ; ^{zhuomingye@hotmail.com} ; Yong-Doo Park^d ; ^f ; ^{parkyd@hotmail.com}

关键词：L-DOPA ; 3 ; 4-dihydroxyphenylalanine ; ANS ; 1-anilinonaphthalene-8-sulfonate ; MD ; molecular dynamics

刊名：International Journal of Biological Macromolecules

出版年：2017

9.Enzyme-mediated stiffening hydrogels for probing activation of pancreatic stellate cells

作者：Hung-Yi Liu^a ; Tanja Greene^b ; Tsai-Yu Lin^b ; Camron S. Dawes^b ; Murray Korc^c ; ^d ; Chien-Chi Lin^a ; ^b ; ^d ; ^{lincc@iupui.edu}

关键词：Hydrogels ; Tyrosinase ; Tissue stiffening ; Pancreatic cancer ; Stellate cells

刊名：Acta Biomaterialia

出版年：2017

10.Polypharmacology of dopamine receptor ligands

作者：S. Butini^a ; K. Nikolic^b ; S. Kassel^c ; H. Brü ; ckmann^c ; S. Filipic^b ; D. Agbaba^b ; S. Gemma^a ; S. Brogi^a ; M. Brindisi^a ; G. Campiani^a ; H. Stark^c ; ^{stark@hhu.de" class="auth_mail" title="E-mail the corresponding author} ; ^{h.stark@zafes.de" class="auth_mail" title="E-mail the corresponding author}

关键词：ACh ; acetylcholine ; AC ; adenylyl cyclase ; APO ; apomorphine ; PD ; Parkinson&rsquo ; s disease ; CNS ; central nervous system ; COMT ; catecholamine O-methyl transferase ; DML ; designed multiple ligands ; L-DOPA ; L-3 ; 4-dihydroxyphenylalanine ; LID ; L-DOPA induced dyskinesia ; DAT ; dopamine reuptake transporter ; EPS ; extrapyramidal symptoms ; GABA ; γ-aminobutyric acid ; IBS ; imidazole binding site ; MAO ; monoamine oxidase ; NET ; norepinephrine reuptake transporter ; SERT ; serotonin reuptake transporter ; THPB ; tetr

刊名：Progress in Neurobiology

出版年：2016

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