搜索页_ 50% effective inhibitory concentration

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1.A novel interpretation of the Fractional Inhibitory Concentration Index: The case Origanum vulgare L. and Leptospermum scoparium J. R. et G. Forst essential oils against Staphylococcus aureus strains

作者：Filippo Fratini^a ; ^b ; ^{filippo.fratini@unipi.it} ; Simone Mancini^a ; Barbara Turchi^a ; Elisabetta Friscia^a ; Luisa Pistelli^b ; ^c ; Giulia Giusti^c ; Domenico Cerri^a ; ^b

关键词：Essential oil ; Staphylococcus aureus ; Fractional inhibitory concentration ; Synergy ; Oregano ; Manuka

刊名：Microbiological Research

出版年：2017

2.A matrix-focused structure-activity and binding site flexibility study of quinolinol inhibitors of botulinum neurotoxin serotype A

作者：William A. Harrell Jr.^a ; ^d ; Rebecca C. Vieira^a ; ^e ; Susan M. Ensel^b ; Vicki Montgomery^a ; Rebecca Guernieri^a ; Vanessa S. Eccard^a ; ^f ; Yvette Campbell^a ; Virginia Roxas-Duncan^a ; ^g ; John H. Cardellina II^a ; ^h ; Robert P. Webb^a ; ^{robert.p.webb6.civ@mail.mil} ; Leonard A. Smith^c

关键词：BoNTs ; botulinum neurotoxins ; BoNT/A ; botulinum neurotoxin serotype A ; HC ; heavy chain ; LC ; light chain ; SNARE ; soluble N-ethylmaleimide-sensitive factor attachment protein receptor ; SNAP-25 ; 25 ; kDa synaptosomal-associated protein ; BIG-IV ; Botulism Immune Globulin Intravenous (Human) ; SAR ; structure-activity relationship ; IC50 ; 50% inhibitory concentration ; MPNHDA ; mouse phrenic nerve hemidiaphragm assay

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

3.Potential uses of Ocimum gratissimum and Hesperozygis ringens essential oils in aquaculture

作者：Guerino Bandeira Jr.^a ; Tanise S. Pê ; s^a ; Etiane M.H. Saccol^a ; Fernando J. Sutili^a ; Waldemar Rossi Jr.^b ; Anelise L. Murari^c ; Berta M. Heinzmann^c ; Maria A. Pavanato^a ; Agueda C. de Vargas^d ; Lenise de L. Silva^e ; Bernardo Baldisserotto^a ; ^{bbaldisserotto@hotmail.com} ; ^{bernardo@smail.ufsm.br}

关键词：CAT ; catalase ; EO ; essential oil ; GC&ndash ; MS ; gas chromatography&ndash ; mass spectroscopy ; GST ; glutathione-S-transferase ; HR ; Hesperozygis ringens ; LC50 ; lethal concentration (the concentration of an essential oil capable of killing 50% of the tested organism) ; LOOH ; lipid hydroperoxide ; LPO ; lipid peroxidation ; MBC ; minimum bactericidal concentration ; MIC ; minimum inhibitory concentration ; NPSH ; non-protein thiols ; OG ; Ocimum gratissimum ; SOD ; superoxide dismutase ; TBARS ; thiobarbituric acid r

刊名：Industrial Crops and Products

出版年：2017

4.Antinociceptive activity and mechanism of action of hydroalcoholic extract and dichloromethane fraction of Amphilophium crucigerum seeds in mice

作者：Samira Dal Toé ; De Prá ; ^a ; ^{samiradaltoe5@gmail.com} ; Paula Ronsani Ferro^a ; ^{ronsaniferropaula@gmail.com} ; Alessandra Marcon Milioli^a ; ^{alessandramilioli@hotmail.com} ; Flá ; via Karine Rigo^a ; ^{flakrigo@hotmail.com} ; Orlando Justo Chipindo^a ; ^{scotlandia1@hotmail.com} ; Camila Camponogara^b ; ^{miladp@zipmail.com.br} ; Rosana Casoti^c ; ^d ; ^{rocasoti@gmail.com} ; Melâ ; nia Palermo Manfron^d ; ^{melpm10@yahoo.com.br} ; Sara Marchesan de Oliveira^b ; ^{saramarchesan@hotmail.com} ; Juliano Ferreira^e ; ^{ferreija99@gmail.com} ; Gabriela Trevisan^a ; ^f ; ^{gabitrev@hotmail.com}

关键词：ALT ; alanine aminotransferase ; ANOVA ; analysis of variance ; AST ; aspartate aminotransferase ; BSA ; bovine serum albumin ; Ca2+) ; calcium ; CFA ; complete Freund's adjuvant ; Crd ; crude extract ; Dcm ; dichloromethane fraction ; DMSO ; dimethyl sulfoxide ; ED50 ; effective dose 50% ; HTAB ; hexadecyltrimethylammonium bromide ; i.g. ; intragastric IC50 ; inhibitory concentration 50% ; Imax ; maximal inhibition ; MPO ; myeloperoxidase ; NAGase ; N-acetyl-β-D-glucosaminidase ; PBS ; phosphate buffer solution ; PWT ; paw with

刊名：Journal of Ethnopharmacology

出版年：2017

5.Anti-flu Effect of Compound Yizhihao Granule and Its Effective Components

作者：Hua Huang ; Hua Yao ; Lin-lin Wang ; Li-jun Si ; Qiao-li Yang ; Zheng-yi Gu ; ^{zhengyi5787@163.com}

关键词：artemisia rupestris ; Compound Yizhihao Granule ; epigoitrin ; influenza virus ; Isatis tinctoria ; rupestonic acid

刊名：Chinese Herbal Medicines

出版年：2017

6.Multi-functional nanoparticles as theranostic agents for the treatment & imaging of pancreatic cancer

作者：L.R. Jaidev^a ; David Raj Chellappan^b ; Dhiraj Vasanth Bhavsar^a ; Ravi Ranganathan^c ; Banudevi Sivanantham^a ; Anuradha Subramanian^a ; Uma Sharma^d ; Narnamangalam R. Jagannathan^d ; Uma Maheswari Krishnan^a ; Swaminathan Sethuraman^a ; ^{swami@sastra.edu}

关键词：Theranostics ; Fluorescent iron oxide nanoparticles ; 3D in vitro ; Multifunctional nanoparticles ; Alginate sponge ; Gemcitabine ; Pancreatic cancer ; MR imaging

刊名：Acta Biomaterialia

出版年：2017

7.Ectoine and hydroxyectoine inhibit thermal-induced aggregation and increase thermostability of recombinant human interferon Alfa2b

作者：Faranak Salmannejad^a ; ^b ; ^{Salmannejad.f@gmail.com} ; Nastaran Nafissi-Varcheh^c

关键词：rhIFNα2b ; Aggregation ; Ectoine ; Hydroxyectoine ; Thermal stress

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

8.Cystatin C peptidomimetic derivative with antimicrobial properties as a potential compound against wound infections

作者：Michał Pikuła^a ; ^{pikula@gumed.edu.pl} ; Maria Smużyńska^b ; Adam Krzystyniak^c ; Maciej Zieliński^a ; Paulina Langa^a ; Milena Deptuła^d ; Adriana Schumacher^d ; Jakub Łata^e ; Mirosława Cichorek^d ; Anders Grubb^f ; Piotr Trzonkowski^a ; Franciszek Kasprzykowski^b ; Sylwia Rodziewicz-Motowidło^b

关键词：Peptidomimetics ; Cystatin C ; Infections ; Wound healing

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

9.Targeted osteosarcoma chemotherapy using RGD peptide-installed doxorubicin-loaded biodegradable polymeric micelle

作者：Zhenhua Fang^a ; ¹ ; Yanpeng Sun^b ; ¹ ; Hong Xiao^a ; Peng Li^a ; Ming Liu^a ; Fan Ding^a ; Wusheng Kan^a ; Runsheng Miao^a ; ^{strongspine@163.com}

关键词：Osteosarcoma ; Targeted chemotherapy ; Nanoparticulate drug delivery system ; RGD

刊名：Biomedicine & Pharmacotherapy

出版年：2017

10.Medicinal plants used in Mexican traditional medicine for the treatment of colorectal cancer

作者：Nadia J. Jacobo-Herrera^a ; ^{nadia.jacobo@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Frida E. Jacobo-Herrera^b ; ^{fridajacobo@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Alejandro Zentella-Dehesa^a ; ^c ; ^{azentell@biomedicas.unam.mx" class="auth_mail" title="E-mail the corresponding author} ; Adolfo Andrade-Cetto^d ; ^{aac@ciencias.unam.mx" class="auth_mail" title="E-mail the corresponding author} ; Michael Heinrich^e ; ^{m.heinrich@ucl.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Carlos Pé ; rez-Plasencia^f ; ^g ; ^{carlos.pplas@campus.iztacala.unam.mx" class="auth_mail" title="E-mail the corresponding author}

关键词：CAM ; Complementary and Alternative Medicine ; GI50 ; growth inhibition 50% ; ED50 ; effective dose ; IC50 ; inhibitory concentration 50% ; EtOH ; ethanol extract ; Hex ; hexane extract ; EtOAc ; ethylacetate extract ; MeOH ; methanol extract ; DCM ; Dichloromethane ; PE ; petroleum ether ; CHCl3 ; chloroform extract ; BuOH ; buthanol extract ; Aq ; aquous extract ; PTOX ; podophyllotoxin ; 6MPTOX ; 6-methoxypodophyllotoxin ; i.p. ; intra peritoneal

刊名：Journal of Ethnopharmacology

出版年：2016

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